بدائل البحث:
significant impairment » significant improvement (توسيع البحث), significant improvements (توسيع البحث), significant impact (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
significant impairment » significant improvement (توسيع البحث), significant improvements (توسيع البحث), significant impact (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
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1121
Data Sheet 4_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.zip
منشور في 2025"…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …"
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1122
Data Sheet 1_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.zip
منشور في 2025"…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …"
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1123
Data Sheet 3_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.zip
منشور في 2025"…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …"
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1124
Table 3_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.xls
منشور في 2025"…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …"
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1125
Table 4_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.xls
منشور في 2025"…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …"
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1126
Table 2_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.xls
منشور في 2025"…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …"
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1127
Data Sheet 2_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.zip
منشور في 2025"…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …"
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1128
Table 5_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.xls
منشور في 2025"…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …"
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1129
Data Sheet 1_Effects of Th1/Th17 and Th2 cytokines on lipid metabolism in differentiated keratinocytes.zip
منشور في 2025"…Introduction<p>Abnormalities of keratinocyte differentiation and impairment of permeability barrier are features of inflammatory skin diseases driven by Th1/Th17 and Th2 immune response, such as psoriasis and atopic dermatitis. …"
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1130
Table 7_Therapeutic potential of five frequently prescribed herbs in obesity-associated Hashimoto’s thyroiditis: insights from efferocytosis regulation.xlsx
منشور في 2025"…Specifically, TCM can reduce thyroid antibody levels and alleviate clinical symptoms without impairing thyroid function. Moreover, TCM offers significant benefits in regulating lipid metabolism and decreasing systemic inflammation.…"
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1131
Table 9_Therapeutic potential of five frequently prescribed herbs in obesity-associated Hashimoto’s thyroiditis: insights from efferocytosis regulation.xlsx
منشور في 2025"…Specifically, TCM can reduce thyroid antibody levels and alleviate clinical symptoms without impairing thyroid function. Moreover, TCM offers significant benefits in regulating lipid metabolism and decreasing systemic inflammation.…"
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1132
Table 2_Therapeutic potential of five frequently prescribed herbs in obesity-associated Hashimoto’s thyroiditis: insights from efferocytosis regulation.xlsx
منشور في 2025"…Specifically, TCM can reduce thyroid antibody levels and alleviate clinical symptoms without impairing thyroid function. Moreover, TCM offers significant benefits in regulating lipid metabolism and decreasing systemic inflammation.…"
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1133
Table 2_Identification of metabolic pathways modulated by GAM and NGAM in the inhibition of Staphylococcus aureus biofilm formation.xlsx
منشور في 2025"…The RNA sequencing analysis of the treated biofilms indicated that, compared to NGAM, GAM leads to a more pronounced downregulation of S. aureus adhesion genes (eno, ebps, and sraP) and genes involved in arginine biosynthesis and tricarboxylic acid (TCA) pathways, which are essential for biofilm proteinaceous structure. The decreased pH in the biofilm environment treated with higher GAM concentrations supports its observed anti-biofilm activity and is likely linked to impaired pH homeostasis resulting from the downregulation of ureABC genes and disruption of urea metabolism, a process interconnected with arginine biosynthesis. …"
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1134
Supplemental file for the manuscript "Unconventional myosin VI is involved in regulation of muscle energy metabolism" by Dominika Wojton, Dorota Dymkowska, Damian Matysniak, Malgor...
منشور في 2025"…Loss of MVI had the most significant effects on SOL, which contains the highest number of mitochondria compared to fast-twitch muscles. …"
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1135
Image 1_Identification of metabolic pathways modulated by GAM and NGAM in the inhibition of Staphylococcus aureus biofilm formation.jpeg
منشور في 2025"…The RNA sequencing analysis of the treated biofilms indicated that, compared to NGAM, GAM leads to a more pronounced downregulation of S. aureus adhesion genes (eno, ebps, and sraP) and genes involved in arginine biosynthesis and tricarboxylic acid (TCA) pathways, which are essential for biofilm proteinaceous structure. The decreased pH in the biofilm environment treated with higher GAM concentrations supports its observed anti-biofilm activity and is likely linked to impaired pH homeostasis resulting from the downregulation of ureABC genes and disruption of urea metabolism, a process interconnected with arginine biosynthesis. …"
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1136
Table 4_Therapeutic potential of five frequently prescribed herbs in obesity-associated Hashimoto’s thyroiditis: insights from efferocytosis regulation.xlsx
منشور في 2025"…Specifically, TCM can reduce thyroid antibody levels and alleviate clinical symptoms without impairing thyroid function. Moreover, TCM offers significant benefits in regulating lipid metabolism and decreasing systemic inflammation.…"
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1137
Table 1_Molecular and epigenetic responses to crowding stress in rainbow trout (Oncorhynchus mykiss) skeletal muscle.xlsx
منشور في 2025"…Background<p>Chronic stress is a critical challenge in fish aquaculture, adversely affecting growth, health, and overall productivity. Among the most significant chronic stressors in intensive farming is crowding, which triggers the release of cortisol, the primary stress hormone in fish. …"
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1138
Table 1_Identification of metabolic pathways modulated by GAM and NGAM in the inhibition of Staphylococcus aureus biofilm formation.xlsx
منشور في 2025"…The RNA sequencing analysis of the treated biofilms indicated that, compared to NGAM, GAM leads to a more pronounced downregulation of S. aureus adhesion genes (eno, ebps, and sraP) and genes involved in arginine biosynthesis and tricarboxylic acid (TCA) pathways, which are essential for biofilm proteinaceous structure. The decreased pH in the biofilm environment treated with higher GAM concentrations supports its observed anti-biofilm activity and is likely linked to impaired pH homeostasis resulting from the downregulation of ureABC genes and disruption of urea metabolism, a process interconnected with arginine biosynthesis. …"
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1139
Image 2_sodA modulates in vitro and in vivo virulence of Yersinia enterocolitica.jpeg
منشور في 2025"…</p>Results<p>The ΔsodA mutant exhibited significantly reduced adhesion to and invasion of epithelial cells, impaired survival within macrophages, and decreased colonization in murine ileum and colon tissues. …"
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1140
Table 1_Mental symptoms in post-COVID syndrome and post-COVID-19 vaccination syndrome: results of a representative population survey.docx
منشور في 2025"…Respondents with only one vaccination reported the highest rate of PCVS symptoms (20.8%), which decreased to 8.9% for those with four or more vaccinations. …"