يعرض 1,141 - 1,160 نتائج من 1,354 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant impairment decrease ))~', وقت الاستعلام: 0.27s تنقيح النتائج
  1. 1141

    Table 8_Therapeutic potential of five frequently prescribed herbs in obesity-associated Hashimoto’s thyroiditis: insights from efferocytosis regulation.xlsx حسب Jiahao Zhou (11385383)

    منشور في 2025
    "…Specifically, TCM can reduce thyroid antibody levels and alleviate clinical symptoms without impairing thyroid function. Moreover, TCM offers significant benefits in regulating lipid metabolism and decreasing systemic inflammation.…"
  2. 1142

    Image 1_sodA modulates in vitro and in vivo virulence of Yersinia enterocolitica.jpeg حسب Yingying Zhang (42910)

    منشور في 2025
    "…</p>Results<p>The ΔsodA mutant exhibited significantly reduced adhesion to and invasion of epithelial cells, impaired survival within macrophages, and decreased colonization in murine ileum and colon tissues. …"
  3. 1143

    Data Sheet 1_Case Report: Dual immunomodulatory and hematologic benefits of rituximab in refractory anemia of ANCA-associated vasculitis.docx حسب Ningjun Shao (20748705)

    منشور في 2025
    "…Concurrently, MPO-ANCA titers decreased from 1:1280 to 1:80, and pulmonary infiltrates resolved. …"
  4. 1144

    Figure 5 from Elraglusib Induces Cytotoxicity via Direct Microtubule Destabilization Independently of GSK3 Inhibition حسب Josh T. Coats (20321355)

    منشور في 2025
    "…<p>Elraglusib impairs proliferation and reduces cell viability in stimulated primary human T cells but does not affect unstimulated cells (<b>A</b> and <b>B</b>). …"
  5. 1145

    Table 6_Therapeutic potential of five frequently prescribed herbs in obesity-associated Hashimoto’s thyroiditis: insights from efferocytosis regulation.xlsx حسب Jiahao Zhou (11385383)

    منشور في 2025
    "…Specifically, TCM can reduce thyroid antibody levels and alleviate clinical symptoms without impairing thyroid function. Moreover, TCM offers significant benefits in regulating lipid metabolism and decreasing systemic inflammation.…"
  6. 1146

    Table 5_Therapeutic potential of five frequently prescribed herbs in obesity-associated Hashimoto’s thyroiditis: insights from efferocytosis regulation.xlsx حسب Jiahao Zhou (11385383)

    منشور في 2025
    "…Specifically, TCM can reduce thyroid antibody levels and alleviate clinical symptoms without impairing thyroid function. Moreover, TCM offers significant benefits in regulating lipid metabolism and decreasing systemic inflammation.…"
  7. 1147

    Table 1_sodA modulates in vitro and in vivo virulence of Yersinia enterocolitica.docx حسب Yingying Zhang (42910)

    منشور في 2025
    "…</p>Results<p>The ΔsodA mutant exhibited significantly reduced adhesion to and invasion of epithelial cells, impaired survival within macrophages, and decreased colonization in murine ileum and colon tissues. …"
  8. 1148

    Table 3_Therapeutic potential of five frequently prescribed herbs in obesity-associated Hashimoto’s thyroiditis: insights from efferocytosis regulation.xlsx حسب Jiahao Zhou (11385383)

    منشور في 2025
    "…Specifically, TCM can reduce thyroid antibody levels and alleviate clinical symptoms without impairing thyroid function. Moreover, TCM offers significant benefits in regulating lipid metabolism and decreasing systemic inflammation.…"
  9. 1149

    Effects of efgartigimod treatment on humoral and cellular immune responses: analysis of T-cell-dependent antibody response in cynomolgus monkeys حسب Ornella Binazon (20718978)

    منشور في 2025
    "…KLH challenges occurred during both the dosing phase and the recovery phase. No statistically significant differences emerged in anti-KLH IgM levels between the efgartigimod and control groups. …"
  10. 1150

    Table 1_Therapeutic potential of five frequently prescribed herbs in obesity-associated Hashimoto’s thyroiditis: insights from efferocytosis regulation.xlsx حسب Jiahao Zhou (11385383)

    منشور في 2025
    "…Specifically, TCM can reduce thyroid antibody levels and alleviate clinical symptoms without impairing thyroid function. Moreover, TCM offers significant benefits in regulating lipid metabolism and decreasing systemic inflammation.…"
  11. 1151

    Table 1_Identification of two KPC variants, KPC-204 and KPC-227, in ST11-K64 Klebsiella pneumoniae during prolonged hospitalization of a single patient.docx حسب Shijun Sun (9287651)

    منشور في 2025
    "…Molecular docking analyses revealed that the D179Y mutation impaired meropenem hydrolysis by decreasing binding affinity. …"
  12. 1152

    Figure 5 from Integrated Molecular Characterization of Patient-Derived Models Reveals Therapeutic Strategies for Treating CIC-DUX4 Sarcoma حسب Marianna Carrabotta (8193039)

    منشور في 2025
    "…The repression of MAPK signaling by the CIC-DUX4 fusion protein renders CDSs mainly dependent on the AKT/mTOR pathway. Trabectedin can impair HMGA2 activity by preventing its binding to promoters, thus inhibiting the transcription of its targets <i>IGF2BP2</i> and <i>IGF2BP3</i> and decreasing IGF2/IGF1R signaling. …"
  13. 1153

    Data Sheet 1_The protective effects and mechanisms of rosmarinic acid against Pseudomonas aeruginosa infection in Caenorhabditis elegans.doc حسب Ying Zhang (40767)

    منشور في 2025
    "…RA treatment at concentrations of 100-300 mg/L dose-dependently reduced the number of PA14 colonies in the nematodes, prolonged the lifespan of the infected nematodes, improved behavioral impairments, decreased lipofuscin and ROS accumulation, and alleviated oxidative stress. …"
  14. 1154

    Loss of b-cell K<sub>ATP</sub> reduces Ca<sup>2+</sup> sensitivity of insulin secretion and <i>Trpm5</i> expression حسب Nathaniel W. York (20410828)

    منشور في 2024
    "…</a><a href="" target="_blank">Glibenclamide pellet-implanted <i>Trpm5</i> KO mice also exhibited significant glucose intolerance. However, this was not as severe as in WT animals, which suggests that decreased expression of <i>Trpm5</i> may play a small role in the disruption of insulin secretion with K<sub>ATP</sub> loss.…"
  15. 1155

    Data Sheet 1_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.pdf حسب Yi Shen (152956)

    منشور في 2025
    "…Interestingly, in the population of over 29 years’ old, a significant interaction between obesity and impaired CRF for PAA was observed (p = 0.018; p = 0.026).…"
  16. 1156

    Table 2_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.docx حسب Yi Shen (152956)

    منشور في 2025
    "…Interestingly, in the population of over 29 years’ old, a significant interaction between obesity and impaired CRF for PAA was observed (p = 0.018; p = 0.026).…"
  17. 1157

    Table 1_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.docx حسب Yi Shen (152956)

    منشور في 2025
    "…Interestingly, in the population of over 29 years’ old, a significant interaction between obesity and impaired CRF for PAA was observed (p = 0.018; p = 0.026).…"
  18. 1158

    Data Sheet 2_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.pdf حسب Yi Shen (152956)

    منشور في 2025
    "…Interestingly, in the population of over 29 years’ old, a significant interaction between obesity and impaired CRF for PAA was observed (p = 0.018; p = 0.026).…"
  19. 1159

    Table 7_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv حسب Zhenyu Zhao (737165)

    منشور في 2025
    "…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…"
  20. 1160

    Image 1_Hippocampus-sparing volume-modulated arc therapy in patients with World Health Organization grade II glioma: a feasibility study.jpeg حسب Renxian Xie (17044863)

    منشور في 2025
    "…Background<p>Radiotherapy can improve the survival rates of patients with glioma; meanwhile, impaired cognitive functions have been brought to the forefront with the offending organ, the radiosensitive hippocampus. …"