بدائل البحث:
significant impairment » significant improvement (توسيع البحث), significant improvements (توسيع البحث), significant impact (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
significant impairment » significant improvement (توسيع البحث), significant improvements (توسيع البحث), significant impact (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
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1201
Presentation 1_Deficits in medial prefrontal cortex parvalbumin expression and distraction-dependent memory in rats and mice in the sub-chronic phencyclidine model for schizophreni...
منشور في 2025"…Introduction<p>Cognitive impairments associated with schizophrenia (CIAS) include deficits in declarative memory. …"
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1202
Data Sheet 1_The MTNR1B Rs724030 variant is associated with islet function and women waist-to-hip ratio in healthy subjects.pdf
منشور في 2025"…Furthermore, we also found significant associations between this variant and IGI, corrected insulin response (CIR), and DIo (All P < 0.001) in female individuals whose waist-to-hip ratio (WHR) is greater than 0.85, with considerable heterogeneity (P<sub>het</sub> = 0.009, 0.030, and 0.049, respectively) to male participants in the NGT individuals, but not in the impaired fasting glucose (IFG)/impaired glucose tolerance (IGT) individuals. …"
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1203
Data Sheet 1_EURAD state-of-the-art report: thermo-hydro-mechanical behaviour of clay buffers at high temperatures.pdf
منشور في 2025"…Given that being able to tolerate higher temperatures would have significant advantages, the work package HITEC of the EURAD project aimed at determining the influence of temperature above 100°C on buffer properties, trying to establish if the safety functions are unacceptably impaired. …"
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1204
Image1_Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO.tiff
منشور في 2024"…Both excessive NET formation and impaired degradation contribute to SLE pathophysiology.…"
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1205
LncRNA MCM3AP-AS1 protects against cerebral ischemia-reperfusion injury via targeting miR-27b-3p
منشور في 2025"…Furthermore, OGD/R treatment inhibited cell viability, increased apoptosis, and promoted inflammatory factors secretion, MCM3AP-AS1 reversed these effects, but miR-27b-3p significantly impaired this reversal. Mechanistically, MCM3AP-AS1 targeted miR-27b-3p.…"
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1206
Data Sheet 1_Integrated physiological, transcriptomic, and metabolomic analyses of Chrysanthemum ‘Boju’ under excessive indole-3-acetic acid stress.pdf
منشور في 2025"…Exogenous IAA treatment also led to a significant reduction in endogenous hormone levels, including gibberellins (GA<sub>3</sub> and GA<sub>4</sub>), abscisic acid (ABA), and IAA, with decreases of 93%, 45%, 99%, and 99%, respectively.Transcriptomic and metabolomic analyses identified 263 differentially expressed metabolites and 144 differentially expressed genes.…"
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1207
Image3_Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO.tif
منشور في 2024"…Both excessive NET formation and impaired degradation contribute to SLE pathophysiology.…"
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1208
Image2_Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO.tif
منشور في 2024"…Both excessive NET formation and impaired degradation contribute to SLE pathophysiology.…"
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1209
Table 1_Dietary quercetagetin attenuates H2O2-induced oxidative damage and preserves meat quality in broilers by modulating redox status and Nrf2/ferroptosis signaling pathway.docx
منشور في 2025"…Meanwhile, the addition of QG to the diet increased the mRNA expressions of Nrf2 and TFR1, showing no significant difference from those of the control group. …"
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1210
Table 1_Associated effects of lipopolysaccharide, oleic acid, and lung injury ventilator-induced in developing a model of moderate acute respiratory distress syndrome in New Zealan...
منشور في 2025"…The LOV group showed the most severe lung injury, significantly decreasing MAP and Cdyn. Pathological and ultrasound scores were considerably higher in the LOV group compared to the OM and LOM groups (p < 0.05). …"
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1211
Table 1_Impact of short-term (24 h) blood pressure variability on 30-days clinical outcomes of acute strokes at two tertiary hospitals in Dar-es-Salaam.docx
منشور في 2025"…Functional outcomes improved significantly by day 30: the Barthel Index increased, and mRS scores decreased. …"
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1212
Image 1_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff
منشور في 2025"…Previously, we discovered that β-cell autophagy is impaired prior to the onset of T1D, implicating this pathway in T1D pathogenesis.…"
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1213
Image 3_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff
منشور في 2025"…Previously, we discovered that β-cell autophagy is impaired prior to the onset of T1D, implicating this pathway in T1D pathogenesis.…"
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1214
Image 4_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tif
منشور في 2025"…Previously, we discovered that β-cell autophagy is impaired prior to the onset of T1D, implicating this pathway in T1D pathogenesis.…"
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1215
Image 2_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff
منشور في 2025"…Previously, we discovered that β-cell autophagy is impaired prior to the onset of T1D, implicating this pathway in T1D pathogenesis.…"
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1216
Data Sheet 1_Andrographolide suppresses chondrosarcoma cell migration and invasion by inhibiting the PI3K/Akt/mTOR signaling pathway and activating autophagy.pdf
منشور في 2025"…Wound healing and transwell assays demonstrated that Andro (5 and 20 μM) treatment significantly reduced the wound healing rate and impaired the migratory and invasive abilities of chondrosarcoma cells after 24 hours (p<0.05) compared to controls. …"
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1217
Table 1_Danggui Buxue Decoction attenuates 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone—induced lung cancer growth in A/J mice by suppressing HIF-1α/VEGF-mediated angiogenesis.do...
منشور في 2025"…By week 20, progressive multifocal opacities emerged alongside reduced pulmonary artery flow, impaired lung function, elevated TNF-α/VEGF, and decreased WBC, lymphocytes, and platelets. …"
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1218
Supporting data for “Androgen receptor modulates chemotherapy response in breast cancer”
منشور في 2025"…For palbociclib, a CDK4/6 inhibitor, AR activation induced RB1 polyubiquitination and degradation, diminishing RB1 levels—a key downstream target of CDK4/6—and thus impairing palbociclib efficacy. Chromatin immunoprecipitation (ChIP) sequencing identified 1,209 AR-regulated genes, with gene ontology (GO) analysis highlighting significant enrichment of ubiquitin-related genes. qPCR validation pinpointed TRIM37, an AR-regulated E3 ligase, as a mediator of RB1 degradation. …"
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1219
Data Sheet 1_Leaf hydraulic decline coordinates stomatal and photosynthetic limitations through anatomical adjustments under drought stress in cotton.docx
منشور في 2025"…By day 28 after drought stress, drought stress significantly impaired leaf hydraulics, as demonstrated by decreases in leaf hydraulic conductivity (K<sub>leaf</sub>) (9.81% under MD, 12.93% under SD) and leaf water potential (5.79% under MD, 17.54% under SD). …"
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1220
Data Sheet 1_Soil microbiome dysbiosis and rhizosphere metabolic dysfunction drive continuous cropping obstacles of Codonopsis tangshen.docx
منشور في 2025"…However, their abundance decreased significantly under continuous cropping, ultimately disrupting soil carbon cycling. …"