يعرض 1,241 - 1,260 نتائج من 1,354 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant impairment decrease ))~', وقت الاستعلام: 0.23s تنقيح النتائج
  1. 1241

    Image 1_Formononetin promotes porcine oocytes maturation and improves embryonic development by reducing oxidative stress.jpeg حسب Na Wang (193263)

    منشور في 2025
    "…It also increased mitochondrial function and ATP levels, reduced intracellular reactive oxygen species, and elevated intracellular GSH levels in both oocytes and embryos. Moreover, FMN significantly decreased autophagy and apoptosis levels in blastocyst cells, potentially via regulation of the Nrf2/Keap1 pathway. …"
  2. 1242

    Glutamate dehydrogenase 2 is required for virulence by facilitating fungal growth in the host hemocoel حسب Yuzhen Lu (4402591)

    منشور في 2025
    "…Deletion of <i>MrGDH2</i> failed to alkalize amino acid-containing media under carbon deprivation, leading to impaired mycelia growth and conidiation. Hemolymph carbohydrates were decreased during <i>M. robertsii</i> infection, and the Δ<i>Mrgdh2</i> mutant exhibited delayed fungal growth and impaired alkalization in hemolymph cultures. …"
  3. 1243

    Data_Sheet_1_MakC and MakD are two proteins associated with a tripartite toxin of Vibrio cholerae.pdf حسب Nandita Bodra (19793703)

    منشور في 2024
    "…Through deletion mutant analysis, we found that individual deletions of makC or makD do not significantly affect MakA expression or secretion. However, the deletion of both makC and makD impairs the expression of MakB, which is directly downstream, and decreases the expression of MakE, which is separated from makCD by two genes. …"
  4. 1244

    Image 1_Yishen-Huoxue formula alleviates renal interstitial fibrosis by attenuating hypoxia-induced renal cell injury and promoting angiogenesis via miR-210/HIF-1α pathway.jpeg حسب Mouying Du (21398510)

    منشور في 2025
    "…</p>Results<p>In vivo, YHF treatment significantly attenuated RIF, protected renal function, increased miR-210 expression, and decreased the expression of HIF-1α, BNIP3, and NIX in the serum exosomes of UUO rats. …"
  5. 1245

    Table 1_Effects of compound probiotics on growth performance, immunity, antioxidant capacity and gut microbiota in weaned rabbits.docx حسب Changchuan Ye (11270642)

    منشور في 2025
    "…</p>Results and discussion<p>Our results showed that dietary supplementation with probiotic significantly promoted growth performance (e.g., increased average daily gain and decreased feed-to-gain ratio), enhanced immune function (reflected by elevated plasmic immunoglobulin levels and reduced pro-inflammatory cytokine concentrations) and improved antioxidant capacity (manifested by higher activities of superoxide dismutase and glutathione peroxidase and lower malondialdehyde content) in weaned rabbits. …"
  6. 1246

    Image 2_Yishen-Huoxue formula alleviates renal interstitial fibrosis by attenuating hypoxia-induced renal cell injury and promoting angiogenesis via miR-210/HIF-1α pathway.jpeg حسب Mouying Du (21398510)

    منشور في 2025
    "…</p>Results<p>In vivo, YHF treatment significantly attenuated RIF, protected renal function, increased miR-210 expression, and decreased the expression of HIF-1α, BNIP3, and NIX in the serum exosomes of UUO rats. …"
  7. 1247

    DataSheet1_Clinical associations of complement-activating collectins, collectin-10, collectin-11 and mannose-binding lectin in preterm neonates.pdf حسب Gabriela Gajek (4060549)

    منشور في 2024
    "…Introduction<p>Premature and low-birthweight infants are at especially high risk of perinatal complications, including impaired thermoregulation, infections and respiratory distress. …"
  8. 1248

    Data Sheet 1_Formononetin promotes porcine oocytes maturation and improves embryonic development by reducing oxidative stress.zip حسب Na Wang (193263)

    منشور في 2025
    "…It also increased mitochondrial function and ATP levels, reduced intracellular reactive oxygen species, and elevated intracellular GSH levels in both oocytes and embryos. Moreover, FMN significantly decreased autophagy and apoptosis levels in blastocyst cells, potentially via regulation of the Nrf2/Keap1 pathway. …"
  9. 1249

    Data Sheet 1_Single-cell transcriptomics reveals predominantly inflammatory endothelial cell responses and suppressed vascular repair in silicosis.pdf حسب Dongli Cao (18700097)

    منشور في 2025
    "…</p>Discussion<p>These results indicate a pathological shift toward inflammation-amplifying endothelial cells and impaired reparative capacity during silicosis progression. …"
  10. 1250

    Data Sheet 2_Single-cell transcriptomics reveals predominantly inflammatory endothelial cell responses and suppressed vascular repair in silicosis.pdf حسب Dongli Cao (18700097)

    منشور في 2025
    "…</p>Discussion<p>These results indicate a pathological shift toward inflammation-amplifying endothelial cells and impaired reparative capacity during silicosis progression. …"
  11. 1251

    Table 1_Single-cell transcriptomics reveals predominantly inflammatory endothelial cell responses and suppressed vascular repair in silicosis.docx حسب Dongli Cao (18700097)

    منشور في 2025
    "…</p>Discussion<p>These results indicate a pathological shift toward inflammation-amplifying endothelial cells and impaired reparative capacity during silicosis progression. …"
  12. 1252

    Table 1_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.docx حسب Xiao Chen (260187)

    منشور في 2024
    "…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …"
  13. 1253

    Image 6_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg حسب Xiao Chen (260187)

    منشور في 2024
    "…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …"
  14. 1254

    Data Sheet 1_Methylglyoxal induces oxidative stress and ferroptosis of renal tubular epithelial cells in acute and chronic kidney injury mice.docx حسب Yongzheng Zhang (1479694)

    منشور في 2025
    "…MG promotes advanced glycation end product (AGE) formation and directly impairs cell function. MG levels are significantly increased in various renal diseases. …"
  15. 1255

    Image 7_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg حسب Xiao Chen (260187)

    منشور في 2024
    "…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …"
  16. 1256

    Image 10_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg حسب Xiao Chen (260187)

    منشور في 2024
    "…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …"
  17. 1257

    Image 8_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg حسب Xiao Chen (260187)

    منشور في 2024
    "…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …"
  18. 1258

    The regulation of AsfR on tmRNA expression mediates bacterial motility and virulence حسب Huimin Chang (21142907)

    منشور في 2025
    "…Consistently, the transcription level of tmRNA was significantly decreased in Δ<i>asfR</i> compared with WT of <i>A. veronii </i>by quantitative real-time PCR (RT-qPCR) analyses. …"
  19. 1259

    Table 1_Mowing of Carex brevicuspis (Cyperaceae) improves food quality for herbivorous geese in Dongting Lake: the potential mechanisms.xlsx حسب Tao Wu (16763)

    منشور في 2025
    "…However, mowing treatments also significantly decreased plant height, density, aboveground biomass, and the biomass of belowground bud banks, which potentially impairs the long-term recovery and sustainability of plant. …"
  20. 1260

    Image 3_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg حسب Xiao Chen (260187)

    منشور في 2024
    "…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …"