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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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921
Table 1_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.xlsx
Published 2025“…</p>Results<p>Low-dose, but not high-dose, tofacitinib significantly increased survival and delayed weight loss. …”
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922
Supplementary Material for: High expression of tetraspanin CD63 predicts poor prognosis in esophageal squamous cell carcinoma
Published 2025“…CD63, a tetraspanin protein and well-known exosomal marker, is implicated in cancer progression; however, the significance of CD63 expression in ESCC remains unclear. …”
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923
Table 1_The relationship between positive future thinking, entrapment, defeat and death-related mental imagery in individuals with and without a suicidal history: an experimental s...
Published 2025“…Mean scores for PFT from pre-to post-negative mood induction decreased significantly in the participants with a history of suicidal thoughts/behaviours but not in those without a suicidal history. …”
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924
All data.
Published 2025“…Metabolomics analysis revealed that inulin treatment significantly modulated the levels of 8 stage-specific metabolites; notably, it increased anti-inflammatory, anti-diabetic and neuroprotective metabolites taurine and dodecanoic acid in prediabetic mice, while decreasing pro-inflammatory mediators including oleamide and adrenic acid. …”
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925
Table 1_Integrated physiological and transcriptomic analyses elucidate the molecular mechanisms of exogenous melatonin-mediated salt tolerance in pomegranate (Punica granatum L.).x...
Published 2025“…In contrast, 400 μM MT treatment effectively mitigated oxidative damage by coordinated activation of superoxide dismutase (SOD,+14.3%), peroxidase (POD,+21.7%), and catalase (CAT,+11.7%) activities, thereby stabilizing membrane integrity. Furthermore, MT significantly alleviated photoinhibition: F<sub>V</sub>/F<sub>M</sub> increased by 39%, Y<sub>II</sub> and qP rose, and NPQ decreased compared to salt-stressed plants, reflecting enhanced protection of the PSII reaction center and optimized light energy allocation. …”
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926
Data Sheet 1_Premature renal epithelial cell senescence promoted by LXN/Rps3/p53 signaling pathway activation increases calcium oxalate crystal deposition by altering macrophage po...
Published 2025“…Furthermore, reducing cellular LXN/Rps3/p53 signaling significantly decreased SASP factors in the culture medium and simultaneously abolished M1-like phenotype macrophage polarization. …”
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927
Table 1_Exploring the role of LOX family in glioma progression and immune modulation.docx
Published 2025“…</p>Results<p>The LOX family was significantly upregulated in low-grade gliomas and strongly associated with poor clinical outcomes. …”
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928
Image 1_Exploring the role of LOX family in glioma progression and immune modulation.jpeg
Published 2025“…</p>Results<p>The LOX family was significantly upregulated in low-grade gliomas and strongly associated with poor clinical outcomes. …”
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929
Table 1_Intrauterine infusion of autologous platelet-rich plasma modulates endometrial immune status and improves pregnancy outcomes in patients with persistent chronic endometriti...
Published 2025“…After PRP treatment, the proportions of endometrial CD8<sup>+</sup> T cells, CD56<sup>+</sup> NK cells, Foxp3<sup>+</sup> Treg cells, and T-bet<sup>+</sup> Th1 cells were significantly decreased in patients with persistent CE. …”
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930
Table 1_Downregulation of HDGF inhibits tumorigenic phenotypes of hypopharyngeal squamous cell carcinoma by suppressing the AKT/mTOR/VEGF pathway.xlsx
Published 2025“…In FaDu HSCC cells, siRNA-mediated HDGF knockdown significantly attenuated proliferation, migration, and invasion. …”
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931
Data Sheet 1_Systemic lipid and glucose modulation differentially affects cognitive function and neuroinflammation in a mouse model of Alzheimer’s disease.xlsx
Published 2025“…Increasing evidence implicates systemic metabolic dysregulation in AD pathogenesis, yet it remains unclear whether modulation of peripheral lipid and glucose metabolism can alter disease progression.…”
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932
Image 1_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.jpeg
Published 2025“…Calcium/Calmodulin signaling pathway has been implicated to the initiation and progression of diverse human cancers. …”
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933
Table 2_Clinical features and genetic analysis of acrodermatitis enteropathica in an ethnic minority infant from Western China: a case report and literature review.xlsx
Published 2025“…Her serum zinc level significantly decreased (0.19 mg/L). Whole-exome sequencing revealed a homozygous c.197G > T(p. …”
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934
Table 1_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx
Published 2025“…Calcium/Calmodulin signaling pathway has been implicated to the initiation and progression of diverse human cancers. …”
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935
Table 1_Clinical features and genetic analysis of acrodermatitis enteropathica in an ethnic minority infant from Western China: a case report and literature review.xlsx
Published 2025“…Her serum zinc level significantly decreased (0.19 mg/L). Whole-exome sequencing revealed a homozygous c.197G > T(p. …”
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936
Data Sheet 1_Plants accumulate abscisic acid after Ralstonia solanacearum infection for enhanced dehydration tolerance and plant resistance.docx
Published 2025“…Many studies have shown that abscisic acid (ABA) has been implicated in wilting, but the role of ABA after R. solanacearum infection remains largely unexplored. …”
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937
Table 2_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx
Published 2025“…Calcium/Calmodulin signaling pathway has been implicated to the initiation and progression of diverse human cancers. …”
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938
Table 1_Case Report: Identification of a novel hemizygous CFAP47 variant in a primary ciliary dyskinesia patient with dual ciliary and flagellar defects.docx
Published 2025“…Experimental validation revealed significantly decreased CFAP47 mRNA levels in the patient’s sperm and the HEK293 cells transfected with mutant plasmid compared to controls, suggesting impaired transcript stability.…”
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939
Data Sheet 1_α-methyltryptophan-mediated protection against diabetic nephropathy in db/db mice as studied with a metabolomics approach.docx
Published 2025“…</p>Results<p>The results of the study demonstrated that α-MT significantly reduced the urinary excretion of albumin and creatinine, improved kidney function, and decreased renal fibrosis in db/db mice. …”
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940
Table 3_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx
Published 2025“…Calcium/Calmodulin signaling pathway has been implicated to the initiation and progression of diverse human cancers. …”