Image 9_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff by Ayaka Goto (20858771)

“…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …”

Data Sheet 1_A multimodal approach for establishing ACTL6A and ERCC1 as chemoresistance genes in locally advanced head and neck cancer.docx by Raushan Kumar Chaudhary (15664043)

“…The median expressions of ERCC1 were significantly increased (p < 0.001) after 50% (0.19) and 100% CRT (0.23) compared to the baseline value (0.14), whereas ACTL6A expression decreased from 4.77 to 3.87 after 50% CRT (p < 0.05) and increased to 5.43 after 100% CRT. …”

Image 8_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff by Ayaka Goto (20858771)

“…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …”

Image 2_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff by Ayaka Goto (20858771)

“…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …”

Effect of curcumin on methotrexate-induced ovarian damage and follicle reserve in rats: the role of PARP-1 and P53 by Mete Keçeci (20479508)

“…In the MTX+Cur group, atretic follicle count decreased (<i>p</i> < 0,05), however, primordial follicle count increased (<i>p</i> < 0,01). …”

Video 1_Kininogen enhances seizure susceptibility in mice possibly through bradykinin-induced modulation of calcium transients in glutamatergic and GABAergic neurons.mp4 by Arijit Ghosh (1304952)

“…Overexpression of kininogen and exogenous bradykinin administration significantly increased pentylenetetrazole-induced seizure susceptibility in mice. …”

Image 5_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff by Ayaka Goto (20858771)

“…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …”

Supplementary file 3_Efficacy of Xiaoyao-san preparations in treating Hashimoto’s thyroiditis: a meta-analysis and systematic review.docx by Chengna Wang (21535973)

“…Four XYS preparations (XY, HHXY, GQXY, and DZXY) increased FT3 and FT4 levels [SMD = 0.13, 95% CI (0.01, 0.61), p = 0.04; SMD = 0.58, 95% CI (0.12, 1.04), p = 0.01] and decreased TSH [SMD = −0.76, 95% CI (−0.98, −0.54), p < 0.00001]. …”

Supplementary file 2_Efficacy of Xiaoyao-san preparations in treating Hashimoto’s thyroiditis: a meta-analysis and systematic review.zip by Chengna Wang (21535973)

“…Four XYS preparations (XY, HHXY, GQXY, and DZXY) increased FT3 and FT4 levels [SMD = 0.13, 95% CI (0.01, 0.61), p = 0.04; SMD = 0.58, 95% CI (0.12, 1.04), p = 0.01] and decreased TSH [SMD = −0.76, 95% CI (−0.98, −0.54), p < 0.00001]. …”

Supplementary file 1_Efficacy of Xiaoyao-san preparations in treating Hashimoto’s thyroiditis: a meta-analysis and systematic review.zip by Chengna Wang (21535973)

“…Four XYS preparations (XY, HHXY, GQXY, and DZXY) increased FT3 and FT4 levels [SMD = 0.13, 95% CI (0.01, 0.61), p = 0.04; SMD = 0.58, 95% CI (0.12, 1.04), p = 0.01] and decreased TSH [SMD = −0.76, 95% CI (−0.98, −0.54), p < 0.00001]. …”

Da-Yuan-Yin decoction suppresses NETs formation, inhibits the IL-23/JAK2/STAT3 signalling pathway, and modulates metabolic profiles and gut microbiota composition in damp-heat synd... by Yun Yang (417125)

“…DYY administration significantly increased total SCFA content. The intervention restored gut microbiota diversity and abundance, while ameliorating metabolic dysregulation.…”

The interaction of COVID-19 and sociodemographic factors on pediatric rehabilitation service initiation by Lynn R. Tanner (21311527)

“…</p> <p>During COVID, service initiation decreased significantly by 23% (<i>p</i> < 0.001), whereas referral rates remained stable. …”

Mitochondrial ROS generated by reverse electron transport in muscles is necessary for critical period heat stress to change NMJ development. by Daniel Sobrido-Cameán (5049743)

“…</i> 25°C control) leads to increased aCC NMJ terminal size and decreased postsynaptic GluRIIA, while not affecting subunit GluRIIB expression. …”

Data Sheet 1_Mitigating ammonium and nitrate leaching in rice-wheat crop rotation: efficacy of neem coated urea and compost co-application.pdf by Sandeep Kumar (145759)

“…Application of 125%-N significantly increased the total mineral N leaching. …”

Phage–antibiotic interactions are determined by the antibiotic, not the phage. by Yuval Mulla (12734528)

“…While the phage amplification rate increases with nitrofurantoin (synergy), it decreases with doxycycline (antagonism). …”

Table 1_Global burden of pneumoconiosis from 1990 to 2021: a comprehensive analysis of incidence, mortality, and socio-demographic inequalities in 204 countries and territories.doc... by Shenyu Zhang (18619540)

“…These rates were generally elevated in low-income and lower-middle-income regions, where males exhibited significantly higher ASIR and ASDR compared to females. …”

Table 1_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx by Jingjing Chen (293564)

“…Immune Microenvironment Profiling linked key genes to altered placental immune cell populations. qRT-PCR confirmed that GLUL and NCL expression decreased and DDX28 and RIOK1 expression increased in clinical placental samples of preeclampsia group.…”

Supplementary file 1_Single-cell transcriptomics identifies FOSL1-regulated IGFBP3+ melanoma subtype as a neuro-immunoregulatory signaling hub facilitating tumor progression.docx by Wenjia Ge (22687361)

“…The C2 subtype was strongly linked with FOSL1 expression, which may affect gene transcription and illness progression. FOSL1 knockdown significantly increased apoptosis and decreased melanoma cell motility and proliferation in vitro.…”

Image 1_A metagenome-wide association study of gut microbiota in hepatitis B virus-related cirrhosis in northwest China.tif by Meirong Feng (22089665)

“…</p>Conclusion<p>HBV-LC patients in Northwest China exhibit altered clinical indicators, gut microbial composition (reduced diversity, increased opportunistic pathogens, decreased beneficial species), and metabolic function. …”

Table 1_Plant-based diets and total and cause-specific mortality: a meta-analysis of prospective studies.docx by Qiwang Mo (9091292)

“…Participants in the highest quintile of both the PDI and hPDI had a significantly decreased risk of all-cause mortality (pooled HR_PDI = 0.85; 95% CI: 0.80–0.90; pooled HR_hPDI = 0.86; 95% CI: 0.81–0.92) compared to participants in the lowest quintile. …”