Data Sheet 2_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.xlsx by Wentong Li (492392)

“…Immune analysis revealed that this molecular chaperone axis modulates neuroinflammation by suppressing naive B cell differentiation (61% reduction) and activating Tregs (55.53% increase). Single-cell resolution analysis showed HSP90AA1 to be specifically overexpressed in oligodendrocytes (72.23%), significantly correlating with glial depletion (4.56% decrease in oligodendrocytes, p<0.01) and aberrant neuronal proliferation (144.23% increase, p=0.0032). …”

Data Sheet 3_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.xlsx by Wentong Li (492392)

“…Immune analysis revealed that this molecular chaperone axis modulates neuroinflammation by suppressing naive B cell differentiation (61% reduction) and activating Tregs (55.53% increase). Single-cell resolution analysis showed HSP90AA1 to be specifically overexpressed in oligodendrocytes (72.23%), significantly correlating with glial depletion (4.56% decrease in oligodendrocytes, p<0.01) and aberrant neuronal proliferation (144.23% increase, p=0.0032). …”

Image_2_High-fat diet mouse model receiving L-glucose supplementations propagates liver injury.JPEG by Johnny Amer (495285)

“…Lipid profile (Steatosis, ADRP and MDA) significantly increased in HFD-fed mice, both Glu supplementations (mainly the L-Glu) increased serum MDA while decreased ADRP. …”

Image_2_High-fat diet mouse model receiving L-glucose supplementations propagates liver injury.JPEG by Johnny Amer (495285)

“…Lipid profile (Steatosis, ADRP and MDA) significantly increased in HFD-fed mice, both Glu supplementations (mainly the L-Glu) increased serum MDA while decreased ADRP. …”

Data Sheet 4_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.xlsx by Wentong Li (492392)

“…Immune analysis revealed that this molecular chaperone axis modulates neuroinflammation by suppressing naive B cell differentiation (61% reduction) and activating Tregs (55.53% increase). Single-cell resolution analysis showed HSP90AA1 to be specifically overexpressed in oligodendrocytes (72.23%), significantly correlating with glial depletion (4.56% decrease in oligodendrocytes, p<0.01) and aberrant neuronal proliferation (144.23% increase, p=0.0032). …”

Image 3_The global burden of neonatal sepsis attributable to air pollution from 1990 to 2021: findings from the global burden of disease study 2021.jpeg by Jiajia Duan (9351878)

“…</p>Conclusion<p>Overall, air pollution remains a significant public health challenge threatening neonatal health. …”

Pediatric CPP with Praat and ADSV (Joshi et al., 2025) by Ashwini Joshi (21594817)

“…Age and <i>F</i>0 are significant predictors of CPP; however, the observed increase in CPP with increasing age in males is primarily due to the substantial decrease in <i>F</i>0 postpuberty. …”

Data Sheet 1_Fatty infiltration and cross-sectional area as indicators of muscle mass in osteoporosis: a meta-regression study.pdf by Genwen Sun (22678739)

“…Meta-regression identified age as a significant moderator, indicating that morphological differences diminish with increasing age. …”

Comparison of the trend of people’s perceptions and the climatic trends (social data: Quantitative data: Household survey (n = 660); qualitative data: Focus group discussions (n =... by Parbati Phuyal (8687400)

“…Depending on the perception, the presence of a trend (yes, no, unclear/mixed) or a trend direction (increase, decrease, unclear) is given. Significance of each data type is presented in detail in Figs <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0317786#pone.0317786.g002" target="_blank">2</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0317786#pone.0317786.g005" target="_blank">5</a>. …”

Table 1_Pandemic predisposing influence for feline lower urinary disorders.xlsx by Carolina C. L. Paulino (21546620)

“…The DP group demonstrated a statistically significant decrease in relapses (p < 0.001) and mortality (p < 0.05) compared to the BP group. …”

Table 2_Pandemic predisposing influence for feline lower urinary disorders.xlsx by Carolina C. L. Paulino (21546620)

“…The DP group demonstrated a statistically significant decrease in relapses (p < 0.001) and mortality (p < 0.05) compared to the BP group. …”

Data Sheet 1_Antibiotic subclasses differentially perturb the gut microbiota in kidney transplant recipients.pdf by Hanbo Dong (19712707)

“…</p>Results<p>Antibiotic administration was associated with a significant decrease in the Shannon alpha diversity index, a decreased abundance of 11 taxa including Eubacterium and Ruminococcus, and an increased abundance of 16 taxa including Enterococcus and Staphylococcus. …”

Data Sheet 1_Amyloid-induced mitochondrial network disruption in neurons monitored by STED super-resolution imaging.pdf by Iuliia Golovynska (18880049)

“…</p>Results<p>In neurons exposed to Aβ, the number of mitochondria increases by 2.6 times, while their total volume decreases by 2.2 times. …”

<b>Metabolic shifts in ratio of ucOcn to cOcn towards bone resorption contribute to age-dependent bone loss in male mice</b> by Bin Wang (16631220)

“…Our findings further demonstrated that the increase in osteoclast activity and the decrease in osteoblast function were significantly corelated with blood levels of ucOcn and cOcn, respectively. …”

Urbanization and climate jointly shape the composition of plant life forms by Zhiwen Gao (19941582)

“…Rising temperatures led to a monotonic decrease in the proportion of perennial herbs and an increase in woody plants. …”

Data Sheet 1_Effects of karst environmental stresses on seed germination and seedling growth of alfalfa (Medicago sativa L.).pdf by Zijun Zhou (3602705)

“…Under moderate calcium stress (40 mM), only a slight decrease in tissue water content was observed. Under moderate drought stress (10% PEG), fresh weight and tissue water content decreased, but dry weight significantly increased. …”

Data Sheet 1_Numerical modeling of the influence of tidal flats on estuaries: the case of the Guadalquivir estuary, SW of the Iberian Peninsula.docx by Pablo Muñoz-López (21603905)

“…Their presence increases water transport through the estuary mouth while reducing tidal amplitude (max. 10% decrease) and delaying tidal wave propagation by a few minutes, resembling the effect of increased bottom friction. …”

Table_1_‘Priming’ protects Piper nigrum L. from Phytophthora capsici through reinforcement of phenylpropanoid pathway and possible enhancement of Piperine biosynthesis.xlsx by M. Indu (14223266)

“…It was observed that pre-treatment of GC for 24 hours resulted in significant reduction of disease symptoms in infected leaves, as evidenced by the marked decrease in the size of lesions, and also delayed the appearance of symptoms up to 72 hpi. …”

DataSheet_1_‘Priming’ protects Piper nigrum L. from Phytophthora capsici through reinforcement of phenylpropanoid pathway and possible enhancement of Piperine biosynthesis.docx by M. Indu (14223266)

“…It was observed that pre-treatment of GC for 24 hours resulted in significant reduction of disease symptoms in infected leaves, as evidenced by the marked decrease in the size of lesions, and also delayed the appearance of symptoms up to 72 hpi. …”

Table_1_‘Priming’ protects Piper nigrum L. from Phytophthora capsici through reinforcement of phenylpropanoid pathway and possible enhancement of Piperine biosynthesis.xlsx by M. Indu (14223266)

“…It was observed that pre-treatment of GC for 24 hours resulted in significant reduction of disease symptoms in infected leaves, as evidenced by the marked decrease in the size of lesions, and also delayed the appearance of symptoms up to 72 hpi. …”