Table 1_Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses.docx by Sielke Caestecker (20749481)

“…</p>Results<p>In a significant number of rats (7/15) we found an increase in hippocampal NA release, field excitatory post synaptic potential (fEPSP) slope and population spike (PS) amplitude, indicating an increase in excitatory neurotransmission and neuronal output. 4/15 rats showed a decrease in NA release without changes in fEPSP slope or PS amplitude, and 4/15 showed no change in NA release.…”

Table 1_Influence of different scion-rootstock combinations on sugars, polyamines, antioxidants and malondialdehyde in grafted grapevines under arid conditions.docx by Sonu Krishankumar (10829367)

“…The shoots improved sugar metabolism, which led to increased resistance to drought. There was a significant increase in glucose sugar content at 75% and 50% FC, which was 85.7% to 133% at V1, 19% to 76.9% at V2, and decreased by 30% and 53% at V4.…”

Supplementary file 1_Full-dose versus reduced-dose comparison of direct oral anticoagulants for extended treatment of venous thromboembolism: a systematic review and meta-analysis... by Renshu Zhang (22775495)

“…</p>Conclusion<p>Reduced-dose DOACs were associated with a significant decrease in the risk of major bleeding/CRNMB compared with full-dose DOACs, but were not associated with a significant increase in the risk of recurrent VTE. …”

Decadal changes in species composition of rare oak <i>Quercus chungii</i> forests with logging history by Wenbin Li (9244088)

“…A larger contribution from balanced abundance variations than abundance gradient to the temporal <i>β </i>diversity suggested that there was no significant consistent increase or decrease in species abundance during this decade. …”

Supplementary Material for: Global, Regional, and National Burden of Neonatal Encephalopathy Due to Birth Asphyxia and Trauma, Its Attributable Risk Factors, 1990-2021: Results fro... by figshare admin karger (2628495)

“…Low SDI regions experienced a substantial 112.9% increase in NEBAT cases, while high-middle SDI regions witnessed a significant 34.8% decrease. …”

Data Sheet 2_MiR-216a-5p protects against high glucose-induced HMC injury by targeting the HMGB1/RAGE signaling pathway.pdf by Juan Zhang (48597)

“…In vitro experiments, in which high glucose concentrations were used to stimulate human mesangial cells (HMCs), demonstrated a significant increase in the protein level of high mobility group box 1 (HMGB1) and a marked decrease in miR-216a-5p expression (all P < 0.05). …”

The role of exosomal hsa-miR-125b-5p and hsa-miR-320c as non-invasive biomarkers in high-radon areas of Kazakhstan by Akmaral Aripova (20575879)

“…</p> <p>Results revealed a 25.4-fold increase in hsa-miR-125b-5p and a 12.5-fold decrease in hsa-miR-320c in participants exposed to high-radon levels compared to controls. …”

DataSheet1_Elucidation of pineapple softening based on cell wall polysaccharides degradation during storage.docx by Fengjun Li (7205768)

“…The process of softening of the fruit corresponded to an increase in the water-soluble pectin (WSP) and 1 M KOH-soluble hemicellulose (HC1) fractions, and a decrease in the acid-soluble pectin (ASP) fraction, which suggested the solubilization and conversion of cellular wall components. …”

Table 1_Effects of Tanreqing injection on the gut microbiota in healthy volunteers.docx by Shiyu Li (144475)

“…The abundance of major genus fluctuated on D7 compared with that prior to treatment, including an increase of unclassified_f_Enterobacteriaceae (13.0611%), a decrease of Bifidobacterium and Escherichia-Shigella (6.887%, 10.487%). …”

Image 1_Global burden of tuberculosis attributable to diet low in whole grains from 1990 to 2021, with projection to 2045.pdf by Xiaoning Lu (206322)

“…However, the burden increased in low Socio-demographic Index (SDI) regions, particularly in Southern Sub-Saharan Africa. …”

Table1_Tle6 deficiency in male mice led to abnormal sperm morphology and reduced sperm motility.docx by Kousuke Kazama (19937214)

“…In addition, Tle6^+/− mice exhibited a significant increase in serum testosterone levels compared to wild-type mice. …”

Data Sheet 1_Abundance, occurrence, and degradation of airborne antibiotic resistance genes in coastal and marine atmospheres.docx by Shijie Jia (5749301)

“…Our results revealed that the airborne ARG abundances and the number of ARG types increased concomitantly with the mass concentrations of particulate matter because of the accumulation effect, but the ratios of ARG abundance/particulate matter concentration gradually decreased. …”

Data Sheet 1_Investigating the impact of microcalcification size and volume on collagenous matrix and tissue mechanics using a tissue-engineered atherosclerotic cap model.xlsx by Imke L. Jansen (22089944)

“…To mimic human microcalcification size and volume, hydroxyapatite microparticles, in two size ranges (diameter up to 5 μm or up to 50 μm) and two volumes (1 v/v% and 5 v/v%) were incorporated homogenously throughout the tissue-engineered model. 5 v/v% of particles caused a significant lowering of the mechanical properties as was shown by a decrease in stiffness and ultimate tensile stress under uniaxial tensile loading. …”

Table 1_Retinal assessment in 143 patients with white matter lesions: the potential of OCTA as an evaluation tool.docx by Dong Zhang (73558)

“…With increasing Fazekas scores, the bilateral foveal avascular zone showed a significant increase (OR = 0.362, OR = 0.458) (p < 0.05). …”

Data Sheet 1_Macrozoobenthos and environmental changing in the Venice Lagoon (Italy).pdf by Federica Cacciatore (694330)

“…Trends in environmental conditions of the water coloumn (sampled seasonally each year) and sediments (sampled concurrently with macrozoobenthos) were also analyzed, highlighting a significant increase/decrease in some parameters, which were then related to dissimilarities in macrozoobenthos abundances. …”

Supplementary file 1_Global, regional, and national burdens of MDR-TB attributable to smoking from 1990 to 2021 with a prediction from 2022 to 2050.docx by Du Dan (22274296)

“…</p>Results<p>The global age-standardized rate (ASR) of smoking-related MDR-TB increased from 1990 to 2021, highlighting a significant disease burden. …”

Supplementary file 1_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.pdf by Ivan Antipenko (22808513)

“…In vitro hypoxia modeling in BeWo b30 cells recapitulated the SCT-specific phenotype and identified a potential regulatory mechanism: a fivefold increase in PCSK9 expression (padj = 3.53e−10) and a 1.5-fold decrease in SNX17 (padj = 1.76e−04)—key regulators that limit lipoprotein receptor recycling. …”

Data Sheet 1_MiR-216a-5p protects against high glucose-induced HMC injury by targeting the HMGB1/RAGE signaling pathway.docx by Juan Zhang (48597)

“…In vitro experiments, in which high glucose concentrations were used to stimulate human mesangial cells (HMCs), demonstrated a significant increase in the protein level of high mobility group box 1 (HMGB1) and a marked decrease in miR-216a-5p expression (all P < 0.05). …”

DataSheet1_Elucidation of pineapple softening based on cell wall polysaccharides degradation during storage.docx by Fengjun Li (7205768)

“…The process of softening of the fruit corresponded to an increase in the water-soluble pectin (WSP) and 1 M KOH-soluble hemicellulose (HC1) fractions, and a decrease in the acid-soluble pectin (ASP) fraction, which suggested the solubilization and conversion of cellular wall components. …”

Table 1_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.xlsx by Ivan Antipenko (22808513)

“…In vitro hypoxia modeling in BeWo b30 cells recapitulated the SCT-specific phenotype and identified a potential regulatory mechanism: a fivefold increase in PCSK9 expression (padj = 3.53e−10) and a 1.5-fold decrease in SNX17 (padj = 1.76e−04)—key regulators that limit lipoprotein receptor recycling. …”