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significant decrease » significantly increased (Expand Search)
increase decrease » increased release (Expand Search), increased crash (Expand Search)
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12461
Image 3_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff
Published 2025“…</p>Results<p>Melatonin treatment significantly reduced ZIKV and DENV-4 replication and the associated inflammatory response in U87-MG cells. …”
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12462
Image 8_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif
Published 2025“…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”
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12463
Table 1_Factors influencing net ecosystem carbon change in cold-temperate coniferous forests of the Da Xing’an Mountains: analysis across developmental stages based on stand, struc...
Published 2025“…</p>Results<p>Our findings demonstrate that: (1) Net Ecosystem Carbon Change (NECC) is co-limited by stand characteristics, structural diversity, and environmental factors, with stand characteristics exerting the strongest influence, primarily via direct effects. (2) As stands develop, the impacts of structural diversity (effect increasing from 8.68% to 16.44%) and soil factors (from 8.80% to 10.30%) on productivity intensify. (3) In contrast, the influence of climate (decreasing from 30.40% to 17.67%) and terrain (from 14.55% to 6.28%) diminishes with advancing growth stages.…”
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12464
<b>Type 1 diabetes depends on CD4-driven expression of the transcriptional repressor, </b><b><i>Bcl6</i></b>
Published 2024“…T follicular helper (Tfh) cells are increased in type 1 diabetic individuals and alterations in Tfh-like cells in the peripheral blood predicted individual responses to abatacept. …”
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12465
Image 2_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff
Published 2025“…</p>Results<p>Melatonin treatment significantly reduced ZIKV and DENV-4 replication and the associated inflammatory response in U87-MG cells. …”
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12466
Table 2_Extraction of anthocyanins from purple sweet potato: evaluation of anti-inflammatory effects in a rheumatoid arthritis animal model, mechanistic studies on inflammatory cel...
Published 2025“…PSPA also altered the gut microbiota, increasing beneficial bacteria like Akkermansia and Lactobacillus. …”
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12467
Table 1_Association between DASH diet and metabolic syndrome in US adults: a cross-sectional study.xlsx
Published 2025“…Objective<p>Metabolic syndrome (MetS) is a global issue increasingly threatening human health and the quality of life. …”
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12468
Shikonin promotes ferroptosis though NSUN2-mediated m<sup>5</sup>C methylation modification of TFRC in acute myelocytic leukemia
Published 2025“…Overexpression of NSUN2 similarly decreased cell viability and increased cell death and ferroptosis, effects that were mitigated upon silencing of TFRC. …”
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12469
Table 3_Extraction of anthocyanins from purple sweet potato: evaluation of anti-inflammatory effects in a rheumatoid arthritis animal model, mechanistic studies on inflammatory cel...
Published 2025“…PSPA also altered the gut microbiota, increasing beneficial bacteria like Akkermansia and Lactobacillus. …”
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12470
Table 2_Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages.doc
Published 2025“…Increased miR-17-5p suppressed MAP3K2 expression and attenuated MAPK signaling, reducing phosphorylation of ERK, JNK, and p38. …”
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12471
Data Sheet 1_Effects of low-temperature stress during rice heading stage on carbon and nitrogen allocation in paddy eco-system of northeastern China.docx
Published 2025“…</p>Results and Discussion<p>Low-temperature stress significantly reduced rice grain yield of JN809 (sensitive to low-temperature stress) and J88 (tolerant to low-temperature stress) varieties by 27.6% and 21.4%, respectively, This stress tendency increased C and N accumulation in rice stems and leaves, while concurrently decreasing C and N accumulation in panicles. …”
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12472
Data Sheet 2_Aurantii Fructus extract alleviates DSS-induced colitis in mice via regulating NF-κB and Nrf2/HO-1 signaling pathways and modulating intestinal microbiota.zip
Published 2025“…Concurrently, AFE enhanced antioxidant capacity by increasing glutathione (GSH) levels, decreasing malondialdehyde (MDA), and activating the Nrf2/HO-1 signaling pathway. …”
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12473
Table 1_Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo.docx
Published 2025“…Monocytes of adjuvant-induced arthritis rats and RA patients expressed less IGFBP5 than normal controls, but its blood levels increased significantly. Adipocytes secreted large amounts of IGFBP5. …”
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12474
Data Sheet 1_Biological mechanisms of sodium nitroprusside in enhancing quality of Radix Paeoniae Rubra and Radix Paeoniae Alba.docx
Published 2025“…Moreover, experiments involving combined treatment with SNP and ROS scavengers demonstrated that ROS act as the key mediator linking exogenous NO to the secondary metabolism of P. lactiflora: scavenging ROS significantly attenuated the SNP-induced accumulation of target secondary metabolites.…”
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12475
Image 11_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif
Published 2025“…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”
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12476
Image 3_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif
Published 2025“…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”
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12477
Table 2_Association between DASH diet and metabolic syndrome in US adults: a cross-sectional study.xlsx
Published 2025“…Objective<p>Metabolic syndrome (MetS) is a global issue increasingly threatening human health and the quality of life. …”
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12478
Table 2_Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo.xlsx
Published 2025“…Monocytes of adjuvant-induced arthritis rats and RA patients expressed less IGFBP5 than normal controls, but its blood levels increased significantly. Adipocytes secreted large amounts of IGFBP5. …”
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12479
Supplementary file 1_Effects of aging and valence on emotional response inhibition: conclusions from a novel stop-signal task.xlsx
Published 2025“…Aging is associated with decreasing cognitive control and inhibition alongside improvements in emotional control and regulation. …”
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12480
Image1_Neutrophil-activating protein in Bacillus spores inhibits casein allergy via TLR2 signaling.jpeg
Published 2024“…Interleukin-12 and interferon-gamma levels increased, whereas serum CAS-specific IgG1 and IgE levels decreased. …”