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significant increases » significant increase (Expand Search), significantly increased (Expand Search), significantly decreased (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
increases decrease » increased release (Expand Search)
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20361
Table 1_Gypenoside XLIX inhibiting PI3K/AKT/FOXO1 signaling pathway mediated neuronal mitochondrial autophagy to improve patients with ischemic stroke.docx
Published 2025“…</p>Results<p>Gypenoside XLIX significantly improved neuronal viability (p < 0.01), reduced apoptosis (p < 0.01), and decreased ROS levels (p < 0.001) in OGD cells. …”
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20362
Supplementary Material for: Alpinia galanga essential oil mitigates gentamycin-induced renal injury: in silico and in vivo studies
Published 2025“…Results: Network Pharmacology suggested Toll-like receptors 4 (TLR4), and Interleukin-1beta (IL-1β) as potential targets of Gal EO components in Genta induced renal toxicity. Gal EO significantly decreased Cr, uric acid, BUN, CysC, NGAL and Kim-1 and the urine albumin/creatinine ratio. …”
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20363
Data Sheet 1_Modulation of TLR7, TYK2 and OAS1 expression during SARS-CoV-2 infection.pdf
Published 2025“…While TLR7 expression decreased across all severity groups as the disease resolved, OAS1 expression persisted in severe cases with higher viremia.…”
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20364
Data Sheet 1_Physical activity of moderate-intensity optimizes myocardial citrate cycle in a murine model of heart failure.pdf
Published 2025“…Interestingly, 8-sWR significantly decreased myocardial citrate content in the presence of unchanged myocardial [BCAAs], ETC proteins content and mtDNA copy number.…”
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20365
Long-Term Effects of Adalimumab in Juvenile Idiopathic Arthritis-Associated Uveitis: 3- and 6-Year Results of the ADJUVITE Trial
Published 2025“…The mean dose of methotrexate decreased significantly from 11.3 ± 4.4 mg/week at the end of the trial to 5.2 ± 6.2 mg/week at the last follow-up (<i>p</i> = 0.002). …”
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20366
DataSheet1_Clinical associations of complement-activating collectins, collectin-10, collectin-11 and mannose-binding lectin in preterm neonates.pdf
Published 2024“…An important finding was the decreased concentrations of CL-10, CL-11 and MBL in respiratory distress syndrome (RDS). …”
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20367
Image2_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…Interference with this pathway significantly influenced the therapeutic effects of CPGB in the 3D-NVU model. …”
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20368
DataSheet1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer...
Published 2024“…Interference with this pathway significantly influenced the therapeutic effects of CPGB in the 3D-NVU model. …”
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20369
Image1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…Interference with this pathway significantly influenced the therapeutic effects of CPGB in the 3D-NVU model. …”
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20370
Supplementary data.xlsx
Published 2025“…However, recent studies have indicated that the telomere length of somatic cells can be drastically decreased in the offspring receiving in vitrofertilization (IVF) therapy, however, the underlying molecular mechanism remains unknown. …”
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20371
TNC promotes bone regeneration via inflammatory macrophage
Published 2024“…Transplantation of macrophages derived from injured periosteum is able to rescue the decreased skeletal stem cells and impaired bone regeneration caused by TNC deficiency. …”
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20372
Glycogen synthase kinase 3 promotes the proliferation of porcine epidemic diarrhea virus by phosphorylating the nucleocapsid protein
Published 2025“…The phosphorylation level significantly decreased after mutation of threonine (Thr) to serine (Ser). …”
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20373
Image 2_ATG16L1 promotes cell migration and invasion in high glucose–induced retinal capillary endothelial cells.tif
Published 2025“…The migration ability and invasion rate of RCECs were significantly higher in the HG group than in the NG group but decreased markedly after transfection with ATG16L1 siRNA, compared with those in the control group (p < 0.01).…”
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20374
Image 1_ATG16L1 promotes cell migration and invasion in high glucose–induced retinal capillary endothelial cells.tif
Published 2025“…The migration ability and invasion rate of RCECs were significantly higher in the HG group than in the NG group but decreased markedly after transfection with ATG16L1 siRNA, compared with those in the control group (p < 0.01).…”
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20375
Data Sheet 1_Lethal and sublethal effects of chemical and bio-insecticides on Spodoptera frugiperda adults: new perspectives for “attract-and-kill” control strategies.pdf
Published 2025“…Sublethal exposure to chlorantraniliprole significantly reduced larval and pupal development durations, decreased pupal weights, and shortened adult longevity in the offspring, without significantly affecting larval mortality, pupation rate, or emergence rate. …”
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20376
MLN IFN-
Published 2025“…<p><b>γ</b><b>production is decreased in the absence of MyD88 and</b><b>αβ</b><b>T cells.…”
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20377
Measurement of interference efficiency of AjNLRC4 or AjCASP-1 by specific siRNA transfection.
Published 2025“…It was found that after the above treatment, the mRNA and protein levels of AjNLRC4 were significantly decreased. Results are representative of at least three independent experiments, and error bars denote the SD of triplicate wells. …”
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20378
Table 1_Ipsilateral transfer of motor skill from upper to lower limb in healthy adults: a randomized controlled trial.docx
Published 2025“…Response time improved significantly in the posttest and retest compared to the pretest in all groups, but it improved significantly in the retest compared to the posttest only in the NO group. …”
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20379
Table 4_ESG performance and carbon emission intensity: examining the role of climate policy uncertainty and the digital economy in China’s dual-carbon era.xlsx
Published 2025“…The analysis reveals that ESG performance significantly alleviates CEI. In addition, CPU weakens the efficiency of ESG initiatives in decreasing CEI due to regulatory unpredictability, while the digital economy’s expansion, although innovative, may exacerbate CEI in regions dependent on fossil fuels. …”
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20380
Table 6_ESG performance and carbon emission intensity: examining the role of climate policy uncertainty and the digital economy in China’s dual-carbon era.xlsx
Published 2025“…The analysis reveals that ESG performance significantly alleviates CEI. In addition, CPU weakens the efficiency of ESG initiatives in decreasing CEI due to regulatory unpredictability, while the digital economy’s expansion, although innovative, may exacerbate CEI in regions dependent on fossil fuels. …”