Design, synthesis and biological evaluation of marine naphthoquinone-naphthol derivatives as potential anticancer agents by Yujuan Li (554062)

“…Among these, Compound <b>13</b>, featuring an oxopropyl group at the <i>ortho</i>-position of quinone group, exhibited the most potent inhibitory effects on HCT116, PC9, and A549 cells, with IC₅₀ values decreasing from 5.27 to 1.18 μM (4.5-fold increase), 6.98 to 0.57 μM (12-fold increase), and 5.88 to 2.25 μM (2.6-fold increase), respectively, compared to compound <b>5</b>. …”

Supplementary file 1_Analysis of microbial composition in different dry skin areas of Beijing women.docx by Jingtao Wang (828021)

“…At the genus level, the relative abundance of Streptococcus was significantly increased in the dry skin group, whereas a decreasing trend was observed for Cutibacterium. …”

Table 1_To elucidate the effect of Ruanjian Qingmai granules on arteriosclerosis obliterans from the perspective of cholesterol efflux.docx by Chenglin Jia (578595)

“…</p>Results<p>Ruanjian Qingmai granules significantly decreased lipid deposition and significantly increased the expression of CYP7A1 mRNA in both zebrafish and HepaRG cells. …”

Supplementary file 2_Clinical efficacy and safety of acupuncture in the treatment for chronic spontaneous urticaria: a systematic review and meta-analysis.docx by Wang Wei (2074669)

“…Furthermore, acupuncture did not significantly increase the incidence of adverse events, which indicates good safety. …”

Supplementary file 4_Clinical efficacy and safety of acupuncture in the treatment for chronic spontaneous urticaria: a systematic review and meta-analysis.docx by Wang Wei (2074669)

“…Furthermore, acupuncture did not significantly increase the incidence of adverse events, which indicates good safety. …”

Supplementary file 5_Clinical efficacy and safety of acupuncture in the treatment for chronic spontaneous urticaria: a systematic review and meta-analysis.docx by Wang Wei (2074669)

“…Furthermore, acupuncture did not significantly increase the incidence of adverse events, which indicates good safety. …”

Supplementary file 1_Clinical efficacy and safety of acupuncture in the treatment for chronic spontaneous urticaria: a systematic review and meta-analysis.docx by Wang Wei (2074669)

“…Furthermore, acupuncture did not significantly increase the incidence of adverse events, which indicates good safety. …”

Supplementary file 3_Clinical efficacy and safety of acupuncture in the treatment for chronic spontaneous urticaria: a systematic review and meta-analysis.docx by Wang Wei (2074669)

“…Furthermore, acupuncture did not significantly increase the incidence of adverse events, which indicates good safety. …”

Data Sheet 1_Wilt disease reshapes rhizosphere microbiota in small yellow ginger soils.docx by Qing Sun (492552)

“…</p>Results<p>Ginger wilt disease significantly altered the rhizosphere soil bacterial community structure and composition: the relative abundance of Proteobacteria increased significantly, primarily due to the enrichment of the genus Ralstonia; conversely, the relative abundance of Acidobacteriota, Firmicutes, and Chloroflexi significantly decreased. …”

Table 1_Organic fertilizer in combination with zeolite enhanced maize yield with lower greenhouse gas emissions in sandy loam soil in North China.docx by Xuexia Wang (3701098)

“…</p>Results<p>Results showed that, compared with the SF treatment, the ZOF treatment significantly increased yield by 14.72–23.61% in each of the 3 years, ZSF by 13.91–15.59% in 2022 and 2023, and OF by 16.92% in 2023. …”

DataSheet1_Global burden of chronic kidney disease in adolescents and young adults, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.docx by Ping Sun (59933)

“…However, the global age-specific death rate significantly decreased from 2.96 (2.76, 3.15) to 2.86 (2.61, 3.11), and the age-specific DALY rate remained stable. …”

Data Sheet 1_Dietary supplementation with polypeptin and bioture improves growth, feed utilization, antioxidant capacity, and disease resistance in juvenile hybrid grouper (Epineph... by Futao Jing (22516817)

“…The results showed that co-supplementation significantly improved multiple performance indicators, exhibiting notable synergistic effects: final body weight, weight gain, and specific growth rate increased, while feed conversion ratio and hepatosomatic index decreased. …”

Effect of TRPML1 on inflammation in lymphedema mice. by Lijie Yang (694492)

“…Compared with that of the SHAM group, the expression of IL-1β/IL-6/TGF-β1/col-1/vimentin/α-SMA genes in the WT group was significantly increased. Compared with that in the WT group, the expression of IL-1β/IL-6/TGF-β1/col-1/vimentin/α-SMA genes was significantly decreased in the TRPML1^−/− group (*<i>p</i> < 0.05, **<i>p</i> < 0.01, ***<i>p</i> < 0.001).…”

Data_Sheet_1_Comparison of antimicrobial activities and resistance mechanisms of eravacycline and tigecycline against clinical Acinetobacter baumannii isolates in China.docx by Xiandi Chen (19729222)

“…The adeABC and adeRS expressions were significantly increased in the only ERV-resistant and both ERV- and TGC-resistant groups, while the adeABC and adeIJK expressions were significantly increased and adeN was significantly decreased in the only TGC-resistant group. …”

Data Sheet 1_Clinical characteristics and outcome of very old (≥90 years) critically ill patients with need for intensive care after surgical intervention.docx by Jöran Lücke (14948623)

“…Background<p>Due to increasing life expectancy and decreasing morbidity, society is aging. …”

DataSheet1_Regulation of hydrogen rich water on strawberry seedlings and root endophytic bacteria under salt stress.docx by Renyuan Wang (10921218)

“…The results showed that under 100 mM NaCl treatment, 50% and 100% HRW treatments significantly increased strawberry biomass by 0.29 g and 0.54g, respectively, wherein, 100% HRW significantly increased the shoot and root length by 15.34% and 24.49%, respectively. …”

Table 1_Engineered miR-214 enriched Schwann cell-derived extracellular vesicles amplify therapeutic efficacy for peripheral neuropathy in T2D mice.docx by Lei Wang (6656)

“…Quantitative RT-PCR and Western blot analyses of sciatic nerve tissues showed that, compared to naïve-EVs, 214-EVs significantly increased miR-214 levels and downregulated axonal inhibitory protein PTEN and the myelination inhibitory protein cJUN. …”

Data Sheet 6_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.zip by Haiyan Liao (6100043)

“…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …”

Data Sheet 1_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.docx by Haiyan Liao (6100043)

“…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …”

Data Sheet 1_Traditional Chinese medicine injections with Tonifying Qi, equivalent effect of regulating energy metabolism, for acute myocardial infarction: a systematic review and... by Huiwen Zhou (6904979)

“…The meta-analysis results demonstrated that the combined application of TCMi-TQ + CT, compared with CT, significantly reduced in-hospital mortality in AMI patients [RR = 0.58, 95% CI (0.51, 0.67), P < 0.05], decreased the incidence of malignant arrhythmia [RR = 0.51, 95%CI(0.42, 0.63), P < 0.05], increased LVEF [MD = 6.52, 95%CI(5.54, 7.50), P < 0.05], and decreased the incidence of adverse events [RR = 0.70, 95%CI(0.60, 0.81), P < 0.05]. …”