Image 1_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif by Minzhen Deng (11267109)

“…Tetramethylpyrazine (TMP), a component of the Chinese medicine, was identified as a potential therapeutic agent. It significantly increased cell viability, reduced ET-1 expression, and mitigated OGD-induced astrocyte damage, as shown by in vitro experiments with ET-1 siRNA and cell lines overexpressing ET-1. …”

Unraveling Microplastic Effects on Gut Microbiota across Various Animals Using Machine Learning by Lingzi Yin (20477620)

“…Our study revealed that mice, compared with other animals, not only exhibit a heightened susceptibility to the toxic effects of microplasticsevidenced by decreased gut microbiota diversity, increased <i>Firmicutes</i>/<i>Bacteroidetes</i> ratios, destabilized microbial networks, and disruption in the equilibrium of beneficial and harmful bacteriabut also possess limited potential to degrade microplastics, unlike earthworms and insects. …”

Data Sheet 1_The gastric microbiome altered by A4GNT deficiency in mice.zip by Dawei Gong (3070773)

“…The relative abundance of mutagenic Desulfovibrio and proinflammatory Prevotellamassilia in these mice was significantly increased, especially 4 weeks after birth. …”

Dataset visualization diagram. by Yaojun Zhang (389482)

“…Results on a specialized dataset reveal that YOLOv8n-BWG outperforms YOLOv8n by increasing the mean Average Precision (mAP) by 4.2%, boosting recognition speed by 21.3% per second, and decreasing both the number of floating-point operations (FLOPs) by 28.9% and model size by 26.3%. …”

Astaxanthin mediated repair of tBHP-Induced cellular injury in chondrocytes by Wenwei Liang (9286389)

“…In the osteoarthritis mouse model, they effectively decreased joint inflammation and increased the expression of chondrocyte markers.…”

The effect of G83R mutation on transthyretin protein structural stability by Xingwang Chen (11225802)

“…Molecular dynamics simulation suggested that the G83R mutation reduces the dynamic stability of TTR by increasing the molecule flexibility. In the thermodynamic stability, the quaternary and tertiary structural stability of TTR G83R is lower than wild-type TTR but significantly higher than TTR V30M. …”

Data Sheet 1_Cellular respiration and amino acid metabolism is altered by dietary oligosaccharides in Salmonella with epithelial cell association.docx by Claire A. Shaw (22382332)

“…However, gene expression analysis revealed significantly induced expression of Specific Pathogenicity Island (SPI) 1 (adj. p < 2.0−6) and 2 (adj. p < 3.0−5) with HMO treatment, opposed to increased fimbriae expression (adj.p < 3.0−3) with MOS treatment. …”

Data Sheet 1_A glycogen derived from sea urchin-Strongylocentyotus internedius shifts macrophages to the M1 phenotype and enhances the anti-pancreatic cancer activity of gemcitabin... by Zhenzhen Deng (3707608)

“…MSGA-induced M1 macrophages decreased the cell viabilities and induced apoptosis of PDAC cells. …”

Dataset sample images. by Yaojun Zhang (389482)

“…Results on a specialized dataset reveal that YOLOv8n-BWG outperforms YOLOv8n by increasing the mean Average Precision (mAP) by 4.2%, boosting recognition speed by 21.3% per second, and decreasing both the number of floating-point operations (FLOPs) by 28.9% and model size by 26.3%. …”

Performance comparison of different models. by Yaojun Zhang (389482)

“…Results on a specialized dataset reveal that YOLOv8n-BWG outperforms YOLOv8n by increasing the mean Average Precision (mAP) by 4.2%, boosting recognition speed by 21.3% per second, and decreasing both the number of floating-point operations (FLOPs) by 28.9% and model size by 26.3%. …”

Table 1_Microbial community and flavor analyses of fermented grains of Furou-type Baijiu.docx by Yanyan Tang (250904)

“…The dominant bacterial species changed from Bacillus subtilis to Acetilactobacillus jinshanensis, and the dominant fungal genus, Saccharomyces sp., gradually increased. The relative abundance of Wickerhamomyces anomalus gradually decreased. …”

Data_Sheet_1_Responses of diazotrophic network structure and community diversity to alfalfa-maize intercropping are soil property-dependent.docx by Jinglei Zhang (311803)

“…However, in the average soil, it was the A/M system that had an altered diazotrophic structure, with an increased abundance of 11 bacterial genera and a decreased abundance of three bacterial genera (p < 0.05).…”

Data Sheet 1_Endothelial Zmiz1 modulates developmental angiogenesis in the retina.pdf by Nehal R. Patel (18522672)

“…Inducible endothelial cell-specific ablation of Zmiz1 postnatally resulted in impaired retinal vascular outgrowth, decreased vascular density, and increased vessel regression. …”

Supplementary Material for: SPECKLE TRACKING ECHOCARDIOGRAPHY IN TWIN PREGNANCIES AND THE ROLE OF GLOBAL LONGITUDINAL STRAIN AND PEAK SYSTOLIC STRAIN: A SYSTEMATIC REVIEW AND META-... by Meireson E. (20224101)

“…The global longitudinal strain in the right and left ventricle and the peak systolic strain in the right ventricle of the recipient MCDA twin is significantly decreased compared to the donor MCDA twin. 2D STE assessment was shown feasible and reproducible in MCDA pregnancies. …”

Table1_Around the clock: unveiling giraffe rest-activity rhythms and social dynamics.docx by Hanna Mebus (19961244)

“…The presence of a male giraffe during one intervention phase significantly altered diurnal activity patterns, increasing standing behaviors and decreasing feeding time. …”

NWB2024_A change of monograph publication patterns after the implementation of the Polish Publishers List by Emanuel Kulczycki (98040)

“…The number of monographs published by publishers not included in PPL significantly decreases while there is a noticeable upward trend in the publication of monographs with Level 2 publishers noted for their prestige and alignment with international standards. …”

A comprehensive assessment of sustainable mortar containing tannery sludge and wheat straw fibre by Rkia Zari (22698213)

“…The density and thermal conductivity of the mortars measured after 28 days decreased with the fibre content increased. Adding 6 wt.% WSF reduces the dry composite’s lighter by 15% and enhances its thermal insulation capacity by about 70%. …”

Data Sheet 1_Impaired SREBP1-mediated regulation of lipid metabolism promotes inflammation in chronic endometritis.pdf by Shigeru Matsuda (17748717)

“…Importantly, EPA-containing phospholipids were also decreased in endometrial tissue from human CE patients. …”

Supplementary Material for: Hair Care Habits and Frontal Fibrosing Alopecia: A Case-Control Study by figshare admin karger (2628495)

“…Cosmetic hair procedures ≥2/year and leave-in product use ≥1/week significantly increased risk (adjusted OR 2.39 and 4.98, respectively). sunscreen use showed no association with FFA in any model. …”

Data Sheet 1_Genetic knockdown of DYRK1A attenuates cognitive impairment, Aβ pathology, tauopathy and neuroinflammatory responses in mouse models of AD.docx by Hyun-ju Lee (7550741)

“…</p>Results and discussion<p>In WT mice, hippocampal DYRK1A overexpression significantly reduced short-term spatial/recognition memory and SynGAP expression while increasing p-P38 levels. …”