Table 4_Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies.docx حسب Zeyi Lv (19344178)

"…</p>Results<p>The meta-analysis showed that quercetin significantly decreased the expression of total IgE, OVA-specific IgE, and histamine, and suppressed the infiltration of eosinophils, macrophages, and lymphocytes. …"

Data Sheet 1_Integrated metabolomics and network pharmacology analysis to reveal the mechanisms of Wenshenyang decoction in the treatment of chronic kidney disease.docx حسب Zongjiang Zhao (21215822)

"…In vitro cell experiments further showed that quercetin, luteolin and kaempferol could significantly activate the cells and reduce the mRNA levels of PTGS2, AKT1, MMP9, EGFR, MMP2, and ANGPTL4, and increase the level of FGFR1, SIRT3 and the glucocorticoid receptor (GR).…"

Image 5_NLRP3 deficiency aggravated DNFB-induced chronic itch by enhancing type 2 immunity IL-4/TSLP-TRPA1 axis in mice.tif حسب Si-Ting Huang (5591432)

"…In Nlrp3^-/- mice, IL-18 expression was downregulated, whereas markers of type 2 immunity, such as IL-4 and thymic stromal lymphopoietin (TSLP), were significantly upregulated in the skin. Furthermore, TRPA1 and its colocalization with the IL-4 receptor were increased in the DRG. …"

Table_1_Differential microbiome features in lake–river systems of Taihu basin in response to water flow disturbance.xlsx حسب Peng Xiao (172430)

"…In the ET region, where water flow disturbances were stronger, microbial richness significantly increased, and phylogenetic relationships were closer, yet variations in community structure were greater than in the ST region, which experienced milder water flow disturbances. …"

Image_1_Differential microbiome features in lake–river systems of Taihu basin in response to water flow disturbance.pdf حسب Peng Xiao (172430)

"…In the ET region, where water flow disturbances were stronger, microbial richness significantly increased, and phylogenetic relationships were closer, yet variations in community structure were greater than in the ST region, which experienced milder water flow disturbances. …"

Data Sheet 1_Evaluation of the epidemiological and economic impact of the ADLIFE intervention on medium- to long-term in patients with advanced chronic disease.pdf حسب Igor Larrañaga (5434382)

"…Emergency visits and consultations with primary care professionals decreased significantly, while specialist consultations increased. …"

Table 2_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx حسب Weilin Cui (21758462)

"…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …"

Table 4_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx حسب Weilin Cui (21758462)

"…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …"

Table 1_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx حسب Weilin Cui (21758462)

"…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …"

Image 1_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.tif حسب Weilin Cui (21758462)

"…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …"

Table 3_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx حسب Weilin Cui (21758462)

"…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …"

Table 6_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx حسب Weilin Cui (21758462)

"…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …"

Table 5_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx حسب Weilin Cui (21758462)

"…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …"

Table 7_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx حسب Weilin Cui (21758462)

"…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …"

Data Sheet 2_Soy-based purified ingredient diet affects mouse gut permeability and the microbiome in fragile X mice.pdf حسب Cara J. Westmark (9302270)

"…Soy protein isolate-based AIN-93G increased gut permeability. Beta-diversity of the cecal microbiome was significantly altered as a function of the four test diets. …"

Table_1_Predicting cancer-related mycobiome aspects in gastrointestinal cancers: a systematic review.docx حسب György Szklenarik (20296893)

"…Observing the interindividual variability, we found that the Ascomycota/Basidiomycota (A/B) ratio from healthy to cancer state decreased in n = 2, increased in n = 1 cases, and did not change significantly in n = 2 studies. …"

Data_Sheet_1_Predicting cancer-related mycobiome aspects in gastrointestinal cancers: a systematic review.DOCX حسب György Szklenarik (20296893)

"…Observing the interindividual variability, we found that the Ascomycota/Basidiomycota (A/B) ratio from healthy to cancer state decreased in n = 2, increased in n = 1 cases, and did not change significantly in n = 2 studies. …"

Table 1_High-concentrate diet supplemented with hydrolysable tannin improves the slaughter performance, intestinal antioxidant ability and barrier function of fattening lambs.docx حسب Jian Ma (170138)

"…Compared with CON group, the carcass weight and intramuscular fat content of lambs in TA1 group were increased (p < 0.05) and the meat shear force was decreased (p < 0.05). …"

Chromatin accessibility profiling of Treg cells in acute urticaria حسب Leilei Wen (3551444)

"…We found that <i>IL1B</i> gene expression was also significantly increased in the skin lesions of both chronic spontaneous urticaria and solar urticaria compared to healthy controls. …"

Data Sheet 1_Soy-based purified ingredient diet affects mouse gut permeability and the microbiome in fragile X mice.pdf حسب Cara J. Westmark (9302270)

"…Soy protein isolate-based AIN-93G increased gut permeability. Beta-diversity of the cecal microbiome was significantly altered as a function of the four test diets. …"