Table 1_Angiotensin converting enzyme inhibitors and angiotensin receptor blockers impact on the gut microbiome: a systematic review.docx by Elisabeth M. Wang (22480771)

“…In the human study, ACEi/ARB use did not significantly alter microbial diversity, but decreased populations of facultative aerobic pathogens including Staphylococcus and Enterobacterales. …”

Table_2_ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1.docx by Živa Frangež (5946392)

“…Results from immunohistochemistry show that the expression of ATG5 and ATG7 is significantly reduced in melanoma tissues compared to benign nevi. …”

Table 1_Natural killer cell as a potential predictive biomarker for early immune checkpoint inhibitor-associated cardiovascular adverse events: a retrospective cohort study.xlsx by Yujuan Wu (2249857)

“…</p>Results<p>ScRNA-seq data revealed decreased CD8+ T and B cell proportions in the CVAEs group, while NK cell proportions increased. …”

Table_2_Diffusion and functional MRI reveal microstructural and network connectivity impairment in adult-onset neuronal intranuclear inclusion disease.docx by Rui Zhu (305217)

“…</p>Results<p>Compared with the HCs, NIID patients showed reduced mean kurtosis (MK), radial kurtosis (RK), axial kurtosis (AK), and kurtosis fractional anisotropy (KFA) values in deep gray matter regions. Significantly decreased MK, RK, AK, KFA and fractional anisotropy (FA), and increased mean diffusivity (MD) values were observed in extensive white matter fiber tracts. …”

Table 1_MFN2-a multifaceted guardian against Parkinson’s pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress.docx by Yan Cheng (149222)

“…</p>Results<p>In PD models, the expressions of DHODH, MFN1, MFN2, GPX4, and FSP1 were significantly down-regulated, and their motor coordination, self-cognitive behavior, and exploration ability were decreased. …”

Image 1_Neuroimaging and molecular mechanism of action of Cang-ai volatile oil in the treatment of vascular cognitive impairment.tif by Bojun Chen (317487)

“…Simultaneously, CAVO reduced the expression of proteins in the endoplasmic reticulum stress pathway (CHOP, pPERK, CHOP, GRP78), the inflammatory factor NLRP3, and the apoptosis pathway (BAX, Bcl-2, Caspase3) (p < 0.05), increased Bcl-2 protein expression (p < 0.05). It also significantly reduced the mRNA expression of CHOP, NLRP3, GRP78, and BAX (p < 0.01).…”

Image 8_Isolation and identification of Alternaria alstroemeriae causing postharvest black rot in citrus and its control using curcumin-loaded nanoliposomes.jpeg by Jie Li (15030)

“…Curcumin-loaded nanoliposomes also enhanced the activities of the enzymes PPO, APX, POD, PAL, GR and CAT of citrus, decreased the O₂⁻ production rate. …”

CO₂fertilisation counteracts the negative effect of poor water quality on the growth and photosynthesis of a Great Barrier Reef coralline alga_datasheets by Bonnie Lewis (20407157)

“…We found complex interactions between factors on algal growth and photosynthetic rates, but overall, growth was significantly enhanced by <i>p</i>CO₂ enrichment under all light and nutrient combinations. …”

Table 2_CqHKT1 and CqSOS1 mediate genotype-dependent Na+ exclusion under high salinity conditions in quinoa.xlsx by Yasufumi Kobayashi (5481530)

“…By contrast, K⁺ accumulation was slightly reduced in the aerial parts but significantly decreased in the roots of all the genotypes. …”

Data Sheet 1_Deglycosylated azithromycin alleviates cisplatin-evoked constipation in mice by altering host metabolome and gut microbiota composition.docx by Xiaoting Gu (3368495)

“…Gut microbiota analysis revealed that Deg-AZM altered the community composition by decreasing Deferribacterota and Pseudomonadota and increasing Bacteroidota, Lactobacillus and Muribaculaceae. …”

Data Sheet 1_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf by Qi Dong (119569)

“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”

Image 1_Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.pdf by Yuanbing Zhu (20538638)

“…Finally, in vivo studies, the results have shown that administering EX-527 to inhibit SIRT1 leads to an increasing in FOXP3 expression and a decreasing in RORγt expression in UC colon tissue. …”

Table 1_Akkermansia muciniphila alleviates cognitive impairment and neuroinflammation induced by blunt chest trauma.docx by Lin Liu (74495)

“…Background<p>Blunt chest trauma, commonly caused by traffic accidents, falls, and violent incidents, results in both direct mechanical injury to the thoracic cavity—leading to increased intrathoracic pressure and vascular rupture—and indirect effects on the central nervous system (CNS), causing extensive damage that severely impacts patient health and quality of life. …”

Supplementary file 1_Petroselinum sativum (Parsley) extract suppresses oxidative stress and inflammatory responses in human keratinocytes and reduces atopic dermatitis symptoms in... by Juan Wang (115708)

“…The results showed that HE extracts of parsley (HEP) contained the highest TPC and TFC and exhibited the strongest antioxidant activity, significantly improving cell viability and reducing ROS levels in t-BHP-treated cells. …”

Data Sheet 1_Aperiodic brain activity changes in patients with stroke following virtual reality-based upper limb robotic rehabilitation: a pilot Randomized Controlled Trial.docx by Maria Cristina Mauro (22449604)

“…</p>Results<p>At T0, the SEI in the sensorimotor cluster of the AH was significantly lower than in the UH. At T1, the SEI in the AH increased together with clinical improvements in upper limb motor function. …”

Table 1_The CD300c antibody CL7 suppresses tumor growth by regulating the tumor microenvironment in non-small cell lung carcinoma.docx by Soyoung Kim (117362)

“…CL7 treatment also modulated the tumor microenvironment by increasing the population of M1 macrophages and CD8⁺ T cells, while decreasing the population of regulatory T cells. …”

Alteration of Ubiquitination in the Brain of ENOPH1 Knockout Mice after Early Ischemic Stroke by Yike Wu (20982007)

“…Our results showed that 4000 ubiquitination-modified sites in 1613 proteins were quantified, with 772 ubiquitinated sites in 464 proteins significantly decreasing or increasing after ENOPH1 knockout (fold change >1.5 or <1/1.5, <i>p</i> < 0.05). …”

Supplementary file 1_Mechanistic insights into the PAI-1 inhibitor PAItrap3: enhancing lipid metabolism in adipose tissue of diabetic db/db mice.xlsx by Linxi Wang (3068649)

“…Regarding the autophagy pathway, PPARGC1B, LC3B, and PGC1α expression levels were increased, while P62 and Parkin levels were decreased. …”

Image 3_Gallic acid attenuates diabetic cardiomyopathy by inhibiting ferroptosis and protecting mitochondria via the TSPO/FTMT pathway.jpeg by Chenchao Zou (22768010)

“…</p>Results<p>GA treatment decreased PTGS2, lactate dehydrogenase, malondialdehyde, ferrous iron, ROS, and oxidized glutathione disulfide (GSSG) levels and increased cell viability, glutathione (GSH) levels, the GSH/GSSG ratio, and GPX4 protein levels in the injury models. …”

S2 File - by Jinfeng Zhao (142391)

“…Exposure to aerobic exercise for 12 weeks significantly improved renal fibrosis and alleviated the intrarenal genetic alterations induced by aging. …”