Image3_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.TIF by Wen Zhou (49050)

“…Purpose<p>The interaction between inflammatory cells and integrin in the endothelium plays a key role during infiltration. …”

Image7_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG by Wen Zhou (49050)

“…Purpose<p>The interaction between inflammatory cells and integrin in the endothelium plays a key role during infiltration. …”

Image9_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG by Wen Zhou (49050)

“…Purpose<p>The interaction between inflammatory cells and integrin in the endothelium plays a key role during infiltration. …”

Table 1_Qinggan Yipi capsule ameliorates hepatic fibrosis in rats by down-regulating the TGF-β1/Smad2/3 signaling pathway and improving gut microbiota imbalance.xlsx by Wenjing Xue (2880686)

“…GO and KEGG analyses indicated that QgYp significantly affects TGF-β signaling pathway. In addition, the results of qPCR and Western blot analysis from both in vitro and in vivo experiments indicated that QgYp significantly downregulated the expression of proteins and mRNA associated with the TGF-β1/Smad2/3 pathway. …”

Data Sheet 1_Qinggan Yipi capsule ameliorates hepatic fibrosis in rats by down-regulating the TGF-β1/Smad2/3 signaling pathway and improving gut microbiota imbalance.docx by Wenjing Xue (2880686)

“…GO and KEGG analyses indicated that QgYp significantly affects TGF-β signaling pathway. In addition, the results of qPCR and Western blot analysis from both in vitro and in vivo experiments indicated that QgYp significantly downregulated the expression of proteins and mRNA associated with the TGF-β1/Smad2/3 pathway. …”

Table 2_Qinggan Yipi capsule ameliorates hepatic fibrosis in rats by down-regulating the TGF-β1/Smad2/3 signaling pathway and improving gut microbiota imbalance.docx by Wenjing Xue (2880686)

“…GO and KEGG analyses indicated that QgYp significantly affects TGF-β signaling pathway. In addition, the results of qPCR and Western blot analysis from both in vitro and in vivo experiments indicated that QgYp significantly downregulated the expression of proteins and mRNA associated with the TGF-β1/Smad2/3 pathway. …”

Data Sheet 2_Qinggan Yipi capsule ameliorates hepatic fibrosis in rats by down-regulating the TGF-β1/Smad2/3 signaling pathway and improving gut microbiota imbalance.pdf by Wenjing Xue (2880686)

“…GO and KEGG analyses indicated that QgYp significantly affects TGF-β signaling pathway. In addition, the results of qPCR and Western blot analysis from both in vitro and in vivo experiments indicated that QgYp significantly downregulated the expression of proteins and mRNA associated with the TGF-β1/Smad2/3 pathway. …”

Data_Sheet_1_Genetically predicted serum metabolites mediate the association between inflammatory proteins and polycystic ovary syndrome: a Mendelian randomization study.CSV by Ming-Jie Jia (18267391)

“…</p>Results<p>The IVW method revealed that the inflammatory proteins IFN-γ (p-value = 0.037, OR = 1.396, 95% CI = 1.020–1.910) and CCL7 (p-value = 0.033, OR = 1.294, 95% CI = 1.021–1.641) were associated with an increased risk of PCOS, while IL-6 (p-value = 0.015, OR = 0.678, 95% CI = 0.495–0.929) and MMP-10 (p-value = 0.025, OR = 0.753, 95% CI = 0.587–0.967) were associated with a decreased risk. No significant evidence suggested an effect of genetically predicted PCOS on inflammatory proteins. …”

Data_Sheet_2_Genetically predicted serum metabolites mediate the association between inflammatory proteins and polycystic ovary syndrome: a Mendelian randomization study.CSV by Ming-Jie Jia (18267391)

“…</p>Results<p>The IVW method revealed that the inflammatory proteins IFN-γ (p-value = 0.037, OR = 1.396, 95% CI = 1.020–1.910) and CCL7 (p-value = 0.033, OR = 1.294, 95% CI = 1.021–1.641) were associated with an increased risk of PCOS, while IL-6 (p-value = 0.015, OR = 0.678, 95% CI = 0.495–0.929) and MMP-10 (p-value = 0.025, OR = 0.753, 95% CI = 0.587–0.967) were associated with a decreased risk. No significant evidence suggested an effect of genetically predicted PCOS on inflammatory proteins. …”

Video 2_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Image1_Oleic acid attenuates asthma pathogenesis via Th1/Th2 immune cell modulation, TLR3/4-NF-κB-related inflammation suppression, and intrinsic apoptotic pathway induction.tif by Soon-Young Lee (4721136)

“…The incidence is expected to increase as the average life expectancy increases, highlighting asthma as a significant health challenge in an aging society. The etiology of asthma is linked to an imbalance of Th1 and Th2 cells, respiratory inflammation, and pulmonary cell proliferation. …”

DataSheet1_Association between various insulin resistance indices and cardiovascular disease in middle-aged and elderly individuals: evidence from two prospectives nationwide cohor... by Yan Li (23143)

“…Multivariate logistic regression analysis indicated that a decreasing eGDR significantly increased the incidence of CVD both presently and in the future. …”

Video 5_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Data Sheet 1_LncRNA NRIR inhibits osteogenesis by promoting macrophage M1 polarization through RSAD2/NF-κB axis in peri-implantitis.pdf by Renshengjie Zhao (22459771)

“…However, our previous studies revealed significant upregulation of NRIR in peri-implantitis, suggesting its potential role in peri-implantitis. …”

Video 1_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Data Sheet 1_Brain injury, endocrine disruption, and immune dysregulation in HIV-positive men who have sex with men with late HIV diagnosis.docx by Yihui He (2936874)

“…A two-way factorial analysis of variance examining the main effects and interactions between groups and neuropsychiatric disorders revealed significant main effects of LD on specific brain regions. …”

Data Sheet 1_The multivalent passive immune-protective vaccines of egg yolk immunoglobulin Y derived from live or inactivated Pseudomonas anguilliseptica against aquaculture pathog... by Pan Cui (5726669)

“…Furthermore, the structures of the kidney, spleen, and intestinal tissues were intact, and the expression of p53 and γH2A.X decreased in the kidney.</p>Conclusion<p>L-PA-IgY and I-PA-IgY can resist multiple bacterial infections and have immunoprotective effects with no significant differences. …”

Causal associations between gut <i>Bifidobacteriaceae</i> and transplant failure: a Mendelian randomization study by Han Yan (126662)

“…The community of bacteria in the gut, known as the gut microbiome, can interact with the immune system. The gut microbiome could therefore influence transplant rejection by altering immune status. …”

Video 6_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Data Sheet 2_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.docx by Lina Ouologuem (22489549)

“…These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”