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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant interest » significant increase (Expand Search), significant interaction (Expand Search), significant increases (Expand Search)
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19541
Data_Sheet_1_MakC and MakD are two proteins associated with a tripartite toxin of Vibrio cholerae.pdf
Published 2024“…Through deletion mutant analysis, we found that individual deletions of makC or makD do not significantly affect MakA expression or secretion. However, the deletion of both makC and makD impairs the expression of MakB, which is directly downstream, and decreases the expression of MakE, which is separated from makCD by two genes. …”
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19542
Image 15_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg
Published 2025“…In vivo, RBM15 depletion significantly delayed tumor progression and enhanced CD8⁺ T cell infiltration and activation in the tumor microenvironment.…”
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19543
Image 4_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.tif
Published 2025“…In vivo, RBM15 depletion significantly delayed tumor progression and enhanced CD8⁺ T cell infiltration and activation in the tumor microenvironment.…”
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19544
Table 1_Integrated transcriptomic analysis of COVID-19 stages and recovery: insights into key gene signatures, immune features, and diagnostic biomarkers through machine learning.x...
Published 2025“…Recovery analysis showed significantly reduced adaptive immune cells at 1 month, with partial recovery by 3 and 6 months. …”
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19545
Data Sheet 8_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf
Published 2025“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”
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19546
Data Sheet 1_Beta-amyloid influences the content and trafficking of beta-amyloid precursor protein via Na,K-ATPase-Src kinase positive feedback loop.pdf
Published 2025“…Furthermore, 100 nM CTS ouabain, a specific Na,K-ATPase ligand, significantly decreased Aβ′s impact on APP and Src kinase activation. …”
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19547
Soil viral and microbial interactions facilitate microbial necromass carbon accumulation in the semiarid typical steppe under altered precipitation_Research data
Published 2025“…The results showed that decreased precipitation significantly reduced microbial necromass carbon (BNC, MNC, and BNC/MNC) and their relative contributions to SOC (BNC/SOC and MNC/SOC), whereas increased precipitation had relatively weaker effects. …”
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19548
Image 11_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg
Published 2025“…In vivo, RBM15 depletion significantly delayed tumor progression and enhanced CD8⁺ T cell infiltration and activation in the tumor microenvironment.…”
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19549
Spatiotemporal dynamics of sea ice volume and their potential drivers in Liaodong Bay, China, using Sentinel-3 data over five ice seasons
Published 2025“…<p>Global sea ice extent has notably decreased in recent decades due to climate warming. …”
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19550
BiFormer structure diagram.
Published 2025“…Significantly, deploying YOLOv8n-BWG on drones yielded promising outcomes in smoke detection, offering innovative approaches and insights for effective smoke monitoring practices.…”
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19551
Image 1_REDD1 attenuates cholestatic liver fibrosis and suppresses PI3K/AKT/mTOR pathway.jpg
Published 2025“…</p>Results<p>RNA sequencing revealed REDD1 was significantly upregulated in BDL-induced fibrotic liver tissue. …”
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19552
Image 6_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif
Published 2025“…</p>Results<p>Behavioral tests revealed that low-frequency EA significantly alleviated depressive-like behaviors and cognitive impairment. …”
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19553
Table_1_Tick cysteine protease inhibitors suppress immune responses in mannan-induced psoriasis-like inflammation.docx
Published 2025“…Tick protease inhibitors have significantly decreased psoriasis symptoms and disease manifestations but had differential effects on inflammatory responses and immune cell populations, suggesting different modes of action of these inhibitors on psoriasis-like inflammation. …”
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19554
Alternative therapeutic strategy for existing aortic aneurysms using mesenchymal stem cell–derived exosomes
Published 2025“…In the MSC-ex group, the expression of IL-1β, TNF-α and MCP-1 decreased, and expression of IGF-1 and TIMP-2 increased. …”
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19555
Image 1_The impact of tumor burden score on prognosis in patients after radical resection of hepatocellular carcinoma: a single-center retrospective study.tif
Published 2024“…</p>Conclusion<p>In patients undergoing radical resection for HCC, higher TBS was significantly related to shorter OS and RFS.</p>…”
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19556
Image 4_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif
Published 2025“…</p>Results<p>Behavioral tests revealed that low-frequency EA significantly alleviated depressive-like behaviors and cognitive impairment. …”
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19557
Image 1_GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma.tif
Published 2024“…The expression of G protein–coupled estrogen receptor 1 (GPER1), a non-classical estrogen receptor, was significantly decreased in proliferating macrophages, and was inversely correlated with macrophage proliferation in HCC tumors. …”
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19558
Data Sheet 15_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf
Published 2025“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”
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19559
Image 5_Photon budgets and the relative effects of CDOM and pigment absorptions on primary production along a coastal salinity gradient.jpeg
Published 2025“…The absorption by CDOM and detritus decreased with increasing salinity, while phytoplankton absorption followed a seasonal succession. …”
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19560
Effects of Feed Enriched with Freshwater Fish Oil on the Nutritional Profile and Growth Performance of Asian Redtail Catfish (Hemibagrus nemurus) Fry
Published 2024“…The results showed that feed enrichment with FFO significantly affected the composition of fatty acids, amino acids, growth performance, and survival (p<0.05). …”