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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant level » significance level (Expand Search), significance levels (Expand Search), significant gender (Expand Search)
level decrease » levels decreased (Expand Search), level increased (Expand Search), teer decrease (Expand Search)
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7321
Protective role of <i>N</i>-acetyl-l-tryptophan against hepatic ischemia-reperfusion injury via the RIP2/caspase-1/IL-1β signaling pathway
Published 2024“…The mRNA and protein expression levels of serine-threonine kinase 2 (RIP2) and interleukin-1β (IL-1β) were significantly increased in the I/R and H<sub>2</sub>O<sub>2</sub> groups when compared with the controls; however, these levels were significantly decreased after l-NAT intervention. …”
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7322
Hypoxia-inducible factor-1α promotes tubulointerstitial fibrosis via the upregulation of <i>Muc4</i>
Published 2025“…Then, the results of transcriptomic analysis and <i>in vivo</i> and <i>in vitro</i> experiments revealed that expression of Mucin 4 (MUC4) was significantly decreased at the transcriptional and protein levels in tubular HIF-1α-knockout mice. …”
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7323
Table 1_Distinct response patterns of endothelial markers to the BNT162b2 mRNA COVID-19 booster vaccine are associated with the spike-specific IgG antibody production.docx
Published 2025“…</p>Results<p>We identified two significantly distinct profiles of endothelial markers response, characterized by either increased or decreased serum levels of endocan and sVCAM. …”
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7324
Effects of exogenous phytohormone 5-ALA on fruit quality and volatile metabolites of ' Meizao ' sweet cherry
Published 2025“…The application of 5-ALA significantly increased the mass fraction of volatile metabolites in 'Meizao' cherry fruits, mainly elevating the levels of aliphatic hydrocarbons and ketones. …”
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7325
Supplementary Material for: Effect of Amla extract on Body Mass Index, waist circumference, total body fat, visceral fat, skeletal muscle mass, body age and related parameters: A r...
Published 2025“…The 500 mg once daily dose also significantly (p<0.05) impacted most parameters. Physical activity levels remained consistent in both groups throughout the study (p>0.05). …”
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7326
Data Sheet 1_The role of lycopene in alleviating soybean meal-induced intestinal injury in an early-weaned piglet model.docx
Published 2025“…Additionally, lycopene reduced apoptosis in small intestinal cells and strengthened intestinal barrier function, as indicated by decreased serum diamine oxidase (DAO) levels. It also improved small intestinal histomorphology, characterized by increased villus height and reduced crypt depth. …”
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7327
Data Sheet 1_Prophylactic administration of lecithinized superoxide dismutase for a murine model of oxaliplatin-induced myelosuppression.pdf
Published 2025“…</p>Results<p>Oxaliplatin administration decreased the white blood cell, platelet, and red blood cell counts and hemoglobin levels in the whole blood of mice. …”
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7328
The effects of CHRM2 knockdown on osteogenic differentiation and cell proliferation.
Published 2025“…(B) The RT-qPCR results showed that the expression of CHRM2 in cells with Si-CHRM2 knockdown decreased significantly. (C) The cell proliferation were measured by OD value at 450 nm, and the observation time points were at 0, 24, 48, 72 and 96 hours. …”
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7329
Trimester-specific thyroid function markers and gestational diabetes risk: evidence from a tertile-based cohort of euthyroid pregnancies
Published 2025“…TSH levels increased, while fT3 and fT4 levels decreased significantly across trimesters (<i>p</i> < 0.001). …”
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7330
Table2_Short-term organic fertilizer substitution increases sorghum yield by improving soil physicochemical characteristics and regulating microbial community structure.xlsx
Published 2024“…After organic fertilizer substitution treatment, higher protein, fat, and total starch levels accumulated in sorghum grains, and the tannin content of grains decreased. …”
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7331
Table1_Short-term organic fertilizer substitution increases sorghum yield by improving soil physicochemical characteristics and regulating microbial community structure.docx
Published 2024“…After organic fertilizer substitution treatment, higher protein, fat, and total starch levels accumulated in sorghum grains, and the tannin content of grains decreased. …”
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7332
Data Sheet 1_The CENPN/STAT3/USP37 signaling axis promotes invasion, migration and metastasis in nasopharyngeal carcinoma.docx
Published 2025“…In vivo studies demonstrated a reduced number of liver metastatic tumors in mice injected with CENPN knockdown cells, with decreased expression levels of CENPN, p-STAT3, and USP37. …”
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7333
Data Sheet 1_Acute hypobaric hypoxia attenuates the anti-fatigue effects of pitolisant by downregulating the expression of organic cation transporter 1 and P-glycoprotein.docx
Published 2025“…Furthermore, OCT1 protein expression decreased after 1 h and 1 day of HH exposure (P < 0.05), while P-gp expression decreased after 1 h (P < 0.05).…”
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7334
Table 1_Effects of selenium-mediated RUNX2 overexpression and its transcriptome alterations on Chondrocyte injury in Kashin Beck disease.docx
Published 2025“…</p>Results<p>The proportion of RUNX2-positive cells in KBD cartilage was significantly higher than in controls. RUNX2 mRNA levels were elevated, whereas methylation levels were reduced in KBD samples. …”
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7335
Supplementary Material for: Efficacy of Spray Cryotherapy on Airway Secretions in Canine Models of Chronic Bronchitis and Mechanism Insights
Published 2025“…SCT effectively treats CB by reducing mucin levels and may lower MUC5AC expression by decreasing acetylcholine and CHRM3.…”
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7336
Image 1_Hyperbaric oxygen pretreatment on endothelial cell injury via heat shock factor 1 in decompression sickness.tif
Published 2025“…Bubble-induced injury significantly decreased the viability of PMVECs and increased the levels of endothelial microparticles, inflammatory cytokines, and endothelial injury markers in culture media. …”
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7337
Image 2_Hyperbaric oxygen pretreatment on endothelial cell injury via heat shock factor 1 in decompression sickness.tif
Published 2025“…Bubble-induced injury significantly decreased the viability of PMVECs and increased the levels of endothelial microparticles, inflammatory cytokines, and endothelial injury markers in culture media. …”
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7338
Supplementary Material for: Transcapillary PO2 Gradients in Contracting Muscle of Rat Model of Sepsis
Published 2025“…The PO2mv and PO2is decreased during the transition from rest to contractions in both groups. …”
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7339
Data Sheet 1_Perilipin 5 alleviates ferroptosis of cardiomyocytes by targeting USP10-p53-TfR proteasome-dependent degradation.docx
Published 2025“…</p>Results<p>We found that after MI, cardiac subcellular iron levels increased and the expression of PLIN5 decreased. …”
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7340
Data Sheet 2_The ERF transcription factor TaERF13-2B functions as a negative regulator of drought tolerance in Arabidopsis and wheat.docx
Published 2025“…In wheat, overexpression of TaERF13-2B under drought stress increased malondialdehyde accumulation, decreased chlorophyll and proline levels, and reduced antioxidant enzyme activity. …”