Image 2_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif by Minzhen Deng (11267109)

“…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …”

Data Sheet 1_Pinostilbene inhibits lung epithelial-mesenchymal transition and delays pulmonary fibrosis by modulating the PI3K/Akt pathway.docx by Xin Yu (124814)

“…Mechanistic studies identified the PI3K/Akt pathway as a target of PIN, with Western blot analysis showing decreased phosphorylation levels of PI3K and Akt. These findings suggest that PIN inhibits pulmonary EMT and delays the progression of pulmonary fibrosis by modulating the PI3K/Akt pathway, providing a promising therapeutic avenue for lung diseases associated with EMT.…”

Image 1_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif by Minzhen Deng (11267109)

“…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …”

Supplementary file 3_Efficacy of Xiaoyao-san preparations in treating Hashimoto’s thyroiditis: a meta-analysis and systematic review.docx by Chengna Wang (21535973)

“…Meta-analysis demonstrated that XYS preparations significantly reduced TPOAb levels [SMD = −0.74, 95% CI (−1.02, −0.46), p < 0.00001]. …”

Supplementary file 2_Efficacy of Xiaoyao-san preparations in treating Hashimoto’s thyroiditis: a meta-analysis and systematic review.zip by Chengna Wang (21535973)

“…Meta-analysis demonstrated that XYS preparations significantly reduced TPOAb levels [SMD = −0.74, 95% CI (−1.02, −0.46), p < 0.00001]. …”

Supplementary file 1_Efficacy of Xiaoyao-san preparations in treating Hashimoto’s thyroiditis: a meta-analysis and systematic review.zip by Chengna Wang (21535973)

“…Meta-analysis demonstrated that XYS preparations significantly reduced TPOAb levels [SMD = −0.74, 95% CI (−1.02, −0.46), p < 0.00001]. …”

Genetic prediction of the relationship between mitochondrial proteins and diabetic polyneuropathy risk: a Mendelian randomization study by Zixiao Wang (6078317)

“…</p> <p>Elevated COA3 levels (OR = 0.5774, 95% CI: 0.4466–0.7465, <i>p</i> < 0.01) decreased DPN risk, while elevated NFU1 (OR: 1.3992, 95% CI: 1.0935–1.7904, <i>p</i> = 0.0075) and SARS2 (OR: 1.3660, 95% CI: 1.0651–1.7520, <i>p</i> = 0.0140) increased risk.…”

The evolution of inharmonicity and noisiness in contemporary popular music by Emmanuel Deruty (20394899)

“…From 1961 to 1972, inharmonicity in popular music, initially only slightly higher than in orchestral music, increased significantly. Between 1972 and 1986, this rise in inharmonicity was accompanied by an increase in noise, but since 1986, both inharmonicity and noise have moderately decreased. …”

<b>Inhibition of NLRP3 Inflammasome Activation by Xylitol Attenuates </b><b><i>Fusobacterium nucleatum</i></b><b>-Driven Preterm Birth</b> by Eui-jeong Noh (21699797)

“…Xylitol also exhibited antimicrobial effects against <i>F. nucleatum</i> within the uterine and placental tissues, correlating with decreased inflammasome activity. Notably, IL-1β levels in the placental labyrinth zone were significantly reduced in xylitol-treated, <i>F. nucleatum</i>-infected mice.…”

Data Sheet 1_Integration of transcriptome and phytohormone analyses reveals antagonistic interactions between jasmonate and auxin signaling pathways in rice (Oryza sativa L.).docx by Xiaoying Wu (695037)

“…Importantly, MeJA application significantly influenced auxin biosynthesis and orchestrated large-scale changes in transcriptional regulation of L-tryptophan (Trp) biosynthesis, as well as indole-3-acetic acid (IAA) biosynthesis, catabolism, signaling transduction, and transport in rice leaves and roots, leading to notably decreased IAA in the leaves and roots, but increased levels of indole-3-carboxylic acid (ICA) and indole-3-carboxaldehyde (ICAld) in the leaves. …”

<b>Differential Myopathic and Transcriptomic Changes in Soleus and Gastrocnemius Muscles in a Novel Chronic Hindlimb Ischemia Rat Model Induced by Endovascular Catheter Occlusion</... by Hanjun Wang (21595280)

“…Histological analysis revealed that IFCO significantly increased levels of fibrosis and decreased myofiber cross-sectional area, in the soleus only. …”

Data Sheet 1_Impaired SREBP1-mediated regulation of lipid metabolism promotes inflammation in chronic endometritis.pdf by Shigeru Matsuda (17748717)

“…Importantly, EPA-containing phospholipids were also decreased in endometrial tissue from human CE patients. …”

Table 1_Synergistic effects of multi-enzyme supplementation on nutrient digestion and absorption in the foregut and hindgut.docx by Fangyuan Chen (2147119)

“…In vitro results demonstrated that MCPC increased the phosphorus and reducing sugar levels in the supernatant during enzymatic hydrolysis. …”

Image 1_Immunomodulatory and anti-inflammatory effects of agave fructans in atopic dermatitis: gut microbiota and short-chain fatty acid implication.tif by Marcela Rios-Carlos (22759823)

“…All AFs significantly decreased dermal mast cell and eosinophil counts, as well as epidermal thickening, with greater efficacy observed at lower doses. …”

Image 2_Immunomodulatory and anti-inflammatory effects of agave fructans in atopic dermatitis: gut microbiota and short-chain fatty acid implication.tif by Marcela Rios-Carlos (22759823)

“…All AFs significantly decreased dermal mast cell and eosinophil counts, as well as epidermal thickening, with greater efficacy observed at lower doses. …”

Image1_Neutrophil-activating protein in Bacillus spores inhibits casein allergy via TLR2 signaling.jpeg by Zhuwei Liang (8762337)

“…Interleukin-12 and interferon-gamma levels increased, whereas serum CAS-specific IgG1 and IgE levels decreased. …”

The prognostic value of the neutrophil-percentage-to-albumin ratio for all-cause and cardiovascular mortality in chronic kidney disease stages G3a to G5: insights from NHANES 2003–... by Jialing Rao (20354623)

“…High levels NPAR exhibited a significantly elevated risk of both all-cause and CVD mortality in the fully adjusted model. …”

Table 1_Organic fertilizer in combination with zeolite enhanced maize yield with lower greenhouse gas emissions in sandy loam soil in North China.docx by Xuexia Wang (3701098)

“…Compared with SF, the levels of available potassium and phosphorus content, dissolved organic carbon content, soil β-glucosidase activity, and microbial biomass carbon and nitrogen concentration in the ZOF treatment were significantly higher by 7.34, 8.90, 19.48, 9.20, 8.42, and 11.29%, respectively; however, soil NH₄⁺-N and NO₃⁻-N were significantly lower by 9.08 and 9.30%, respectively. …”

Integrated bioinformatic and experimental study links cyclin B1/B2 to poor prognosis and immune infiltration in endometrial cancer by Haikun Yang (14815742)

“…High CCNB1/CCNB2 expression was significantly associated with shorter survival in EC patients. …”

Table 1_Exploring the alleviating effects of Bifidobacterium metabolite lactic acid on non-alcoholic steatohepatitis through the gut-liver axis.docx by Hongmei Zhao (250090)

“…</p>Results<p>In vivo findings indicated that, in comparison to CBX group (Control group without antibiotic treatment), NAFLD/CBX group (NAFLD group without antibiotic administration) and NAFLD/ABX group (NAFLD group with antibiotic administration) exhibited increased liver-to-body weight ratio, higher lipid droplet accumulation, aggravated liver histopathological damage, and elevated levels of AST (Aspartate Aminotransferase), ALT (Alanine Aminotransferase), TC (Total Cholesterol), TG (Triglycerides), LDL-C (Low-Density Lipoprotein Cholesterol), IL-6 (Interleukin-6), TNF-α (Tumor Necrosis Factor-alpha), IL-1β (Interleukin-1 beta), and NLRP3-related molecules, while HDL-C (High-Density Lipoprotein Cholesterol) levels significantly decreased. …”