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significant level » significance level (Expand Search), significance levels (Expand Search), significant gender (Expand Search)
level decrease » levels decreased (Expand Search), level increased (Expand Search), teer decrease (Expand Search)
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7761
Image 1_Atractylenolide-I prevents abdominal aortic aneurysm formation through inhibiting inflammation.tif
Published 2025“…</p>Results<p>ATL-I inhibited the dilatation of the abdominal aorta and decreased the incidence of AAA. ATL-I alleviated the infiltration of macrophages in the adventitia and reduced the levels of proinflammatory factor IL-1β and IL-6 in the aorta and circulatory system, while increasing the expression of anti-inflammatory factor IL-10. …”
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7762
Table 2_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le...
Published 2025“…<p>Optimizing fermentation duration is critical for producing high-quality cigar tobacco leaves This study examines changes in microorganisms and metabolites during CTL fermentation at four time points: 0 days (T0), 25 days (T1), 50 days (T2), and 75 days (T3). We observed a decreasing trend in total soluble sugars, starch, total nitrogen, and nicotine levels as fermentation progressed. …”
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7763
Table 1_Therapeutic potential of Cervi Cornus Colla in zebrafish bone injury: implications for aquaculture.docx
Published 2025“…In Tg (mpeg1: EGFP) zebrafish, CCC treatment significantly decreased macrophages-associated green fluorescence, suggesting that the extract suppressed the activation of macrophages caused by LPS. …”
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7764
Table 6_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.docx
Published 2025“…Under salt and osmotic stress, A. chroococcum W5 metabolomic profiling revealed adaptive responses, including elevated levels of osmoprotectants (proline, glycerol) and oxidative stress markers such as 2-hydroxyglutarate, while putrescine and glycine decreased.…”
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7765
Glucose-6-phosphatase catalytic subunit 3 enhances host resistance to porcine epidemic diarrhea virus through regulating glycolysis/gluconeogenesis
Published 2025“…We established PEDV infection models in both breeds and analyzed differences by assessing cytokine levels, viral loads, and histological changes in jejunal tissues. …”
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7766
Table 1_Intramuscular iron supplementation enhances intestinal barrier function in weaned piglets challenged with enterotoxigenic Escherichia coli.docx
Published 2025“…</p>Results<p>Intramuscular iron supplementation alleviated the clinical symptoms of bacterial infection, decreasing the diarrhea rate by 53% and mitigating the inflammatory response with lower serum levels of pro-inflammatory cytokines, such as TNF-α, IL-6, and IL-8. …”
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7767
CBD treatment did not affect activity, anxiety, or improve aging-related declines in strength of SAMP8 mice.
Published 2025“…<p>A: The elevated maze test showed that 12 mos-old mice (red bar) and 4 mos-old mice (white bar) that received vehicle had similar anxiety levels to one another. 12 mos-old mice that received both 3 (blue bar) or 30 mg/Kg (gray bar) of CBD showed decreased anxiety compared to the 12 mos-old mice that received vehicle (red bar) (O-Veh) (N = 10 ~ 12 per group). …”
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7768
Image 1_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.tif
Published 2025“…Functional studies demonstrated that RBM15 loss led to increased expression of fumarate hydratase (FH). This led to decreased levels of fumarate, a metabolite known to suppress anti-tumor immune responses. …”
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7769
Table 2_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.docx
Published 2025“…Under salt and osmotic stress, A. chroococcum W5 metabolomic profiling revealed adaptive responses, including elevated levels of osmoprotectants (proline, glycerol) and oxidative stress markers such as 2-hydroxyglutarate, while putrescine and glycine decreased.…”
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7770
Image 3_Human beta defensin-2 protects the epithelial barrier during methicillin-resistant Staphylococcus aureus infection in chronic rhinosinusitis with nasal polyps.tif
Published 2025“…In addition, the hBD-2 protein was negatively correlated with the Lund–Mackay CT score and was positively correlated with the neutrophil levels in CRSwNP. The presence of hBD-2 significantly reduced the invasive ability of MRSA in HNECs. …”
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7771
Presentation_1_The impact of challenge and hindrance stressors on knowledge hiding: the mediating role of job crafting and work withdrawal.pdf
Published 2024“…The findings indicate that both challenge and hindrance stressors significantly increase knowledge hiding, with hindrance stressors exerting a more pronounced effect. …”
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7772
Image 5_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le...
Published 2025“…<p>Optimizing fermentation duration is critical for producing high-quality cigar tobacco leaves This study examines changes in microorganisms and metabolites during CTL fermentation at four time points: 0 days (T0), 25 days (T1), 50 days (T2), and 75 days (T3). We observed a decreasing trend in total soluble sugars, starch, total nitrogen, and nicotine levels as fermentation progressed. …”
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7773
Image 1_Human beta defensin-2 protects the epithelial barrier during methicillin-resistant Staphylococcus aureus infection in chronic rhinosinusitis with nasal polyps.tif
Published 2025“…In addition, the hBD-2 protein was negatively correlated with the Lund–Mackay CT score and was positively correlated with the neutrophil levels in CRSwNP. The presence of hBD-2 significantly reduced the invasive ability of MRSA in HNECs. …”
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7774
Data Sheet 1_Influence of the polysaccharide capsule on virulence and fitness of Klebsiella pneumoniae.pdf
Published 2025“…Infections of Galleria mellonella larvae showed a significantly decreased virulence potential of the CPS-deficient mutant.…”
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7775
Image 2_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le...
Published 2025“…<p>Optimizing fermentation duration is critical for producing high-quality cigar tobacco leaves This study examines changes in microorganisms and metabolites during CTL fermentation at four time points: 0 days (T0), 25 days (T1), 50 days (T2), and 75 days (T3). We observed a decreasing trend in total soluble sugars, starch, total nitrogen, and nicotine levels as fermentation progressed. …”
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7776
Design, synthesis and biological evaluation of marine naphthoquinone-naphthol derivatives as potential anticancer agents
Published 2024“…Further mechanistic studies revealed that compound <b>13</b> significantly induced cell apoptosis by increasing the expression levels of cleaved caspase-3 and reducing Bcl-2 proteins through downregulating the EGFR/PI3K/Akt signalling pathway, leading to the inhibition of proliferation in HCT116 and PC9 cells. …”
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7777
Image 14_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg
Published 2025“…Functional studies demonstrated that RBM15 loss led to increased expression of fumarate hydratase (FH). This led to decreased levels of fumarate, a metabolite known to suppress anti-tumor immune responses. …”
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7778
Image 5_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.tif
Published 2025“…Under salt and osmotic stress, A. chroococcum W5 metabolomic profiling revealed adaptive responses, including elevated levels of osmoprotectants (proline, glycerol) and oxidative stress markers such as 2-hydroxyglutarate, while putrescine and glycine decreased.…”
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7779
Table 1_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le...
Published 2025“…<p>Optimizing fermentation duration is critical for producing high-quality cigar tobacco leaves This study examines changes in microorganisms and metabolites during CTL fermentation at four time points: 0 days (T0), 25 days (T1), 50 days (T2), and 75 days (T3). We observed a decreasing trend in total soluble sugars, starch, total nitrogen, and nicotine levels as fermentation progressed. …”
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7780
Disruption of Astrocyte Communication by Carbenoxolone During Shockwave-Induced Stress
Published 2025“…</p><p dir="ltr">Results showed that 50 µM CBX prolonged calcium signal duration (FWHM), while 100 µM CBX shortened it toward control levels. Peak calcium intensity was significantly reduced at 100 µM CBX, and both rise and fall rates of calcium signals decreased with increasing CBX concentration. …”