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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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male decrease » small decrease (Expand Search), marked decrease (Expand Search), rate decreased (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant male » significant main (Expand Search), significant cause (Expand Search), significant gap (Expand Search)
male decrease » small decrease (Expand Search), marked decrease (Expand Search), rate decreased (Expand Search)
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1421
Data Sheet 1_Influence of water temperature on feed intake, appetite control, and energy allocation in Atlantic salmon (Salmo salar) post-smolt.pdf
Published 2025“…Plasma ghrelin (Ghrl) levels decreased significantly at elevated temperature. Temperature negatively affected the ghrl1 expression in the stomach, and the expression dynamics of the orexigenic neuropeptide npya and anorexigenic pomca paralogues in the hypothalamus, which were lower at 15°C. …”
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1422
Data Sheet 1_Exploring long COVID in pediatric patients: clinical insights from a long COVID clinic.docx
Published 2025“…Overall symptom burden decreased significantly over time (p < 0.001). Vaccination status at baseline was not associated with difference in symptom duration on initial presentation (p = 0.4). …”
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1423
Supplementary Material for: Global, regional, and national burden of motor neuron disease: a systematic analysis of prevalence, incidence, deaths, and DALYs with projections to 203...
Published 2025“…Results: From 1990 to 2021, the global number of MND cases, deaths, and DALYs increased significantly, while the age - standardized prevalence and incidence rates decreased. …”
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1424
Image 1_MFN2-a multifaceted guardian against Parkinson’s pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress.tif
Published 2025“…</p>Results<p>In PD models, the expressions of DHODH, MFN1, MFN2, GPX4, and FSP1 were significantly down-regulated, and their motor coordination, self-cognitive behavior, and exploration ability were decreased. …”
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1425
Data Sheet 1_Metabolic adaptation to acute metabolic stress via PFKFB3 upregulation in rodent beta cells.doc
Published 2025“…Knockdown of PFKFB3 or pharmacological inhibition of glycolysis resulted in decreased insulin secretion and impaired glucose tolerance. …”
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1426
Data Sheet 2_Long-term aerobic exercise improves learning memory capacity and effects on oxidative stress levels and Keap1/Nrf2/GPX4 pathway in the hippocampus of APP/PS1 mice.docx
Published 2024“…The level of ROS in the hippocampal region was significantly reduced by aerobic exercise (p < 0.05), with decreased Keap1 protein expression of and increased Nrf2, HO-1, GPX4 protein expression (p < 0.05).…”
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1427
Data Sheet 1_Long-term aerobic exercise improves learning memory capacity and effects on oxidative stress levels and Keap1/Nrf2/GPX4 pathway in the hippocampus of APP/PS1 mice.zip
Published 2024“…The level of ROS in the hippocampal region was significantly reduced by aerobic exercise (p < 0.05), with decreased Keap1 protein expression of and increased Nrf2, HO-1, GPX4 protein expression (p < 0.05).…”
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1428
Table 1_Trends and projections of Hepatitis A incidence in eastern China from 2007 to 2021: an age-period-cohort analysis.docx
Published 2024“…</p>Conclusion<p>The incidence of Hepatitis A in Jiangsu Province has significantly decreased from 2007 to 2021, primarily due to public health measures and vaccination programs. …”
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1429
Protective role of <i>N</i>-acetyl-l-tryptophan against hepatic ischemia-reperfusion injury via the RIP2/caspase-1/IL-1β signaling pathway
Published 2024“…Similarly, IL-1β activity and caspase-1 activity were significantly decreased in the H<sub>2</sub>O<sub>2</sub> group when compared with the controls, after l-NAT intervention.…”
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1430
Table 1_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx
Published 2025“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”
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1431
Table 1_Electroacupuncture improves scopolamine hydrobromide induced dry eye in mice via inhibiting ocular surface inflammation and regulating the HMGB1-related signaling pathways....
Published 2025“…The levels of HMGB1, RAGE, TLR2, TLR4, and IL-6 were significantly decreased while IL-10 level was significantly increased after EA treatment, indicating that EA may improve dry eye surface inflammation by inhibiting HMGB1-related signaling pathways.…”
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1432
Table 2_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx
Published 2025“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”
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1433
Data Sheet 1_Hybridization promotes growth performance by altering rumen microbiota and metabolites in sheep.docx
Published 2024“…Acetate, propionate, and total volatile fatty acid (VFA) concentrations in the DH group were higher than those in the HH group, whereas NH<sub>3</sub>-N concentration decreased in the DH and SH groups. Metagenomic analysis revealed that several Prevotella and Fibrobacter species were significantly more abundant in the DH group, contributing to an increased ability to degrade dietary cellulose and enrich their functions in enzymes involved in carbohydrate breakdown. …”
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1434
Data Sheet 1_TSG-6 promotes healing of critical-sized bone defects in mice.pdf
Published 2025“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”
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1435
Table 3_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx
Published 2025“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”
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1436
Data Sheet 2_TSG-6 promotes healing of critical-sized bone defects in mice.pdf
Published 2025“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”
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1437
Data Sheet 1_BAM8-22 targets spinal MrgC receptors to modulate UPRmt activity in the mechanism of bone cancer pain.docx
Published 2025“…Background<p>Bone cancer pain (BCP) significantly impacts patients’ overall quality of life. …”
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1438
Image 1_Yishen-Huoxue formula alleviates renal interstitial fibrosis by attenuating hypoxia-induced renal cell injury and promoting angiogenesis via miR-210/HIF-1α pathway.jpeg
Published 2025“…</p>Results<p>In vivo, YHF treatment significantly attenuated RIF, protected renal function, increased miR-210 expression, and decreased the expression of HIF-1α, BNIP3, and NIX in the serum exosomes of UUO rats. …”
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1439
Image 2_Yishen-Huoxue formula alleviates renal interstitial fibrosis by attenuating hypoxia-induced renal cell injury and promoting angiogenesis via miR-210/HIF-1α pathway.jpeg
Published 2025“…</p>Results<p>In vivo, YHF treatment significantly attenuated RIF, protected renal function, increased miR-210 expression, and decreased the expression of HIF-1α, BNIP3, and NIX in the serum exosomes of UUO rats. …”
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1440
Image 1_Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice.tiff
Published 2025“…In the present study, we investigated the pathogenesis and the mechanisms underlying goblet cell down-regulation in the early phase of infection.</p>Methods<p>Male C57BL/6 mice were orally infected with 300 oocysts. …”