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Data Sheet 1_Prognostic value of left atrial strain in significant aortic valve disease: a systematic review and meta-analysis.pdf
Published 2025“…Background<p>Previous studies on aortic valve disease have mainly focused on the left ventricle, but increasing evidence suggests that left atrial strain also has prognostic value in significant aortic valve disease.</p>Objective<p>To systematically evaluate the prognostic value of left atrial strain in significant aortic valve disease.…”
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Effect of NPRC KO on renal function.
Published 2025“…KO of NPRC decreased cystatin C levels in Gq mice but the difference was not statistically significant.…”
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Effect of NPRC KO on podocyte proteins.
Published 2025“…<p>(<b>7</b>A & <b>7</b>B) Expression of nephrin and podocin mRNAs were significantly decreased in glomerular preparations from Gq mice compared to controls and expression of both podocyte proteins were preserved by podocyte specific KO of NPRC. (7C & 7D) The pattern of nephrin protein expression was similar to the mRNA results, but the differences were not statistically significant.…”
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Effect of podocyte specific NPRC KO on systemic BP and albuminuria.
Published 2025“…<p>(<b>4</b>A) Systolic BP was similarly decreased in both groups of Gq mice compared to controls, but this difference was not statistically significant. …”
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Effect of NPRC KO on fibrotic markers.
Published 2025“…Podocyte specific KO of NPRC decreased expression of both fibronectin and Col4 alpha-1, which was statistically significant for Col4 alpha-1. …”