يعرض 1,721 - 1,740 نتائج من 1,887 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant new decrease ))~', وقت الاستعلام: 0.31s تنقيح النتائج
  1. 1721

    <i>Edwardsiella piscicida</i> employs C3 derivative to mediate internalization and infection via the teleost-specific receptor حسب Mo-Fei Li (21624535)

    منشور في 2025
    "…When PoCD18 was knocked down or blocked, bacterial infection and tissue lesions were significantly decreased. Mechanistically, the intracellular domain of PoCD18 subsequently interacted with PoCytohesin and triggered the phosphorylation of the phosphatidylinositol 3-kinase (PI3K)/serine-threonine protein kinase (Akt) signalling pathway. …"
  2. 1722

    Data Sheet 1_Autoimmune thyroid disease and human health: a systematic review of Mendelian randomization studies.xlsx حسب Peijin Li (220400)

    منشور في 2025
    "…MR analyses indicated that AITD significantly increased the risk of coronary atherosclerosis, deep venous thrombosis, chronic obstructive pulmonary disease, major depression, diabetic neuropathy, carpal tunnel syndrome, neuromyelitis optica spectrum disorder, diabetic retinopathy, childhood absence epilepsy, rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis, inflammatory bowel disease, crohn's disease, vitiligo, myasthenia gravis, alopecia areata, type 1 and type 2 diabetes, sarcoidosis, frozen shoulder, drug eruptions, cataract, early age-related macular degeneration, pernicious anemia, Helicobacter pylori infection, temporomandibular disorders, migraine, frailty, primary biliary cholangitis, knee osteoarthritis, gout, and osteoporosis, while decreasing the risk of lung cancer, polyneuropathies, allergic rhinitis, telomere length, and serum vitamin A levels. …"
  3. 1723

    Supplementary file 2_Oxymatrine for inflammatory bowel disease in preclinical studies: a systematic review and meta-analysis.docx حسب Xuan Zhao (356028)

    منشور في 2025
    "…The data analysis results indicated that the disease activity index (DAI), histopathological score (HS), interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB), and myeloperoxidase (MPO) activity in the IBD animal models significantly decreased following intervention with oxymatrine. …"
  4. 1724

    Table 1_Oxymatrine for inflammatory bowel disease in preclinical studies: a systematic review and meta-analysis.docx حسب Xuan Zhao (356028)

    منشور في 2025
    "…The data analysis results indicated that the disease activity index (DAI), histopathological score (HS), interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB), and myeloperoxidase (MPO) activity in the IBD animal models significantly decreased following intervention with oxymatrine. …"
  5. 1725

    Tilmicosin inhibits the infections of currently prevalent porcine reproductive and respiratory syndrome viruses via the downregulation of CD163 expression حسب Ming Qiu (762714)

    منشور في 2025
    "…Flow cytometric analysis indicated that anti-inflammatory may reverse the downregulation effect of tilmicosin on CD163, while pro-inflammatory mediators can enhance the downregulation effect of tilmicosin on CD163, which leads to increased and decreased replication of PRRSV, respectively. These findings demonstrate that tilmicosin can inhibit PRRSV replication via the reduction of CD163 expression, which provides new insights into anti-PRRSV mechanisms of tilmicosin.…"
  6. 1726

    Table 1_Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.xls حسب Dang Li (16400478)

    منشور في 2024
    "…<p>Keloid scarring is a fibroproliferative disease of the skin, which can significantly impact one’s quality of life through cosmetic concerns, physical discomfort (itchy; painful), restricted movement, and psychological distress. …"
  7. 1727

    Table_2_ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1.docx حسب Živa Frangež (5946392)

    منشور في 2025
    "…Results from immunohistochemistry show that the expression of ATG5 and ATG7 is significantly reduced in melanoma tissues compared to benign nevi. …"
  8. 1728

    Table 1_MFN2-a multifaceted guardian against Parkinson’s pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress.docx حسب Yan Cheng (149222)

    منشور في 2025
    "…</p>Results<p>In PD models, the expressions of DHODH, MFN1, MFN2, GPX4, and FSP1 were significantly down-regulated, and their motor coordination, self-cognitive behavior, and exploration ability were decreased. …"
  9. 1729

    Image 13_Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.jpeg حسب Dang Li (16400478)

    منشور في 2024
    "…<p>Keloid scarring is a fibroproliferative disease of the skin, which can significantly impact one’s quality of life through cosmetic concerns, physical discomfort (itchy; painful), restricted movement, and psychological distress. …"
  10. 1730
  11. 1731

    Image 1_Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.jpeg حسب Dang Li (16400478)

    منشور في 2024
    "…<p>Keloid scarring is a fibroproliferative disease of the skin, which can significantly impact one’s quality of life through cosmetic concerns, physical discomfort (itchy; painful), restricted movement, and psychological distress. …"
  12. 1732

    Table 1_Akkermansia muciniphila alleviates cognitive impairment and neuroinflammation induced by blunt chest trauma.docx حسب Lin Liu (74495)

    منشور في 2025
    "…Targeting the gut-brain axis may offer new strategies for preventing and treating trauma-induced neurological disorders.…"
  13. 1733

    Supplementary file 3_Oxymatrine for inflammatory bowel disease in preclinical studies: a systematic review and meta-analysis.docx حسب Xuan Zhao (356028)

    منشور في 2025
    "…The data analysis results indicated that the disease activity index (DAI), histopathological score (HS), interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB), and myeloperoxidase (MPO) activity in the IBD animal models significantly decreased following intervention with oxymatrine. …"
  14. 1734

    Image 12_Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.jpeg حسب Dang Li (16400478)

    منشور في 2024
    "…<p>Keloid scarring is a fibroproliferative disease of the skin, which can significantly impact one’s quality of life through cosmetic concerns, physical discomfort (itchy; painful), restricted movement, and psychological distress. …"
  15. 1735

    <b>Mystery of Deep Soil Organic Carbon Dynamics Uncovered through Long-term Conservation Tillage Experiments</b> حسب Jianye Li (8914520)

    منشور في 2025
    "…Our findings suggest that long-term NT in boreal <a href="" target="_blank">agroecosystem</a>s affects SOC dynamics in both topsoil and deep soil, providing new insights into carbon sequestration under long-term conservation tillage. …"
  16. 1736

    Image 11_Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.jpeg حسب Dang Li (16400478)

    منشور في 2024
    "…<p>Keloid scarring is a fibroproliferative disease of the skin, which can significantly impact one’s quality of life through cosmetic concerns, physical discomfort (itchy; painful), restricted movement, and psychological distress. …"
  17. 1737

    Data Sheet 1_Exploring long COVID in pediatric patients: clinical insights from a long COVID clinic.docx حسب Dina Kamel (22434430)

    منشور في 2025
    "…Overall symptom burden decreased significantly over time (p < 0.001). Vaccination status at baseline was not associated with difference in symptom duration on initial presentation (p = 0.4). …"
  18. 1738

    Image 2_Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.jpeg حسب Dang Li (16400478)

    منشور في 2024
    "…<p>Keloid scarring is a fibroproliferative disease of the skin, which can significantly impact one’s quality of life through cosmetic concerns, physical discomfort (itchy; painful), restricted movement, and psychological distress. …"
  19. 1739
  20. 1740

    Image 4_Behavioral alterations in antibiotic-treated mice associated with gut microbiota dysbiosis: insights from 16S rRNA and metabolomics.tiff حسب Asma Bibi (12057986)

    منشور في 2025
    "…The KEGG enrichment analysis of serum and brain samples showed that amino acid metabolism pathways, such as tryptophan metabolism, threonine metabolism, serotonergic synapsis, methionine metabolism, and neuroactive ligand-receptor interaction, were significantly decreased in antibiotic-treated mice. Our study demonstrates that long-term antibiotic use induces gut dysbiosis and alters metabolic responses, leading to the dysregulation of brain signaling molecules and anxiety-like behavior. …"