Atg14 deficiency in Tregs induces a type-I-dominant lymphoproliferative disease and cell-intrinsic reductions in eTregs. by Erienne G. Norton (9612079)

Loss of Vps34 reduces Treg suppressive function and is associated with the development of type-I-dominant inflammatory disease. by Erienne G. Norton (9612079)

Vps34 supports Treg maintenance in lymphoid and non-lymphoid tissues. by Erienne G. Norton (9612079)

“…Two-tailed Student <i>t</i> test (<b>A</b>–<b>D</b>, <b>F</b>–<b>I</b>) or Benjamini–Hochberg test (<b>E</b>); NS, not significant. Data are compiled from 15 (<b>A</b>, <b>F</b>), 12 (<b>B</b>), 5 (<b>C</b>, <b>G</b>, <b>I</b>), 6 (<b>D</b>, lung and liver; <b>H</b>), or 2 (<b>D</b>, colon LP) independent experiments. …”

Atg14 does not contribute to terminal eTreg generation during perinatal life. by Erienne G. Norton (9612079)

Chromatin accessibility analysis of perinatal Vps34-deficient Tregs. by Erienne G. Norton (9612079)

“…Two-tailed Student <i>t</i> test (<b>A</b>, <b>B</b>, <b>I</b>), Benjamini–Hochberg test (<b>C</b>), Wilcoxon rank-sum test (<b>G</b>), Fisher’s exact tes<i>t</i> (<b>H</b>), or binomial test (<b>J</b>); NS, not significant. Data are compiled from ≥4 (<b>A</b>) or 10 (<b>B</b>) independent experiments. …”

Atg14 plays a cell-intrinsic role in orchestrating eTreg survival but not terminal differentiation. by Erienne G. Norton (9612079)

“…Pearson’s correlation (<b>A</b>), Benjamini–Hochberg test (<b>B</b>), two-tailed Student <i>t</i> test (<b>C</b>–<b>E, G</b>–<b>J</b>), or Fisher’s exact test (<b>F</b>); NS, not significant. Data are compiled from ≥2 (<b>C</b>, <b>E</b>) or 4 (<b>D</b>, <b>H</b>–<b>J</b>) independent experiments. …”

Vps34 orchestrates transcriptional and epigenetic remodeling events corresponding to terminal eTreg differentiation during perinatal life. by Erienne G. Norton (9612079)

“…Wilcoxon rank-sum test (<b>A</b>, <b>B</b>; <b>J</b>, right), Benjamini–Hochbert test (<b>C</b>), two-tailed Student <i>t</i> test (<b>D</b>, <b>I</b>), Fisher’s exact test (<b>F</b>–<b>H</b>), or bionomial test (<b>J</b>, left); NS, not significant. Data are compiled from 10 independent experiments (<b>D</b>). …”

Disruption of <i>shk-1</i> increases susceptibility to bacterial pathogens. by Longjun Pu (20685717)

Bortezomib/venetoclax suppressed G1-S transition in sLCLs expressing EBNA-3C, LMP-1 and bortezomib-induced Noxa. by Kam Pui Tam (19746865)

G1 cell cycle arrest and sub-G1 population induced by bortezomib/venetoclax were stronger in sLCL expressing BHRF-1, EBNA-3C, LMP-1 and NOXA. by Kam Pui Tam (19746865)

Effects of bortezomib/venetoclax on the growth suppression of sLCL 381 xenografts in SCID mice. by Kam Pui Tam (19746865)

NMN improves neurological function and survival after cardiac arrest in mice. by Daiki Kaito (12514087)

NMN attenuates neuronal injury after cardiac arrest in mice. by Daiki Kaito (12514087)

Effect of RNAi inhibition of TsNas14 expression on <i>T. spiralis</i> infection. by Qingbo Lv (11631289)

NMN increases SIRT3 expression at both mRNA and protein levels in the brain 6 h after cardiac arrest. by Daiki Kaito (12514087)

<i>lin-15b(-)</i> animals exhibit altered intestinal nuclear morphology. by Ashwin Seetharaman (615458)

Screening for K⁺ channel mutants with altered susceptibility to <i>V. cholerae.</i> by Longjun Pu (20685717)

<i>shk-1</i> mutants exhibit defects in mitochondrial homeostasis. by Longjun Pu (20685717)

Modest MAD1 upregulation sensitizes to colon tumorigenesis. by Sarah E. Copeland (13951506)

Zika virus replicates efficiently in the zebrafish model and induces morphological defects. by Aïssatou Aïcha Sow (20371233)

“…Data are shown as means ± SEM. **** P ≤ 0.0001; ns = not significant; one-way ANOVA. (F-G) Total ZIKV RNA (F) and ZIKV negative strand (-) RNA (G) levels in whole larvae pools (6–15 larvae) at 1, 2 and 3 dpf were determined using ddPCR. …”