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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant part » significant gap (Expand Search), significant portion (Expand Search), significant factor (Expand Search)
part decrease » point decrease (Expand Search), bfrt decreased (Expand Search), a decrease (Expand Search)
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521
Data Sheet 1_Elocalcitol, a fluorinated vitamin D derivative, prevents high-fat diet-induced obesity via SCAP downregulation and miR-146a-associated mechanisms.pdf
Published 2025“…The data indicate that elocalcitol’s reduction of SCAP is at least partly mediated by miR-146a modulation.</p>Conclusion<p>The study demonstrates that elocalcitol prevents HFD-induced obesity and metabolic syndrome in mice, likely by inhibiting SREBP-mediated lipogenesis and upregulating miR-146a. …”
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522
Update on trimethylamine N-oxide (TMAO) as a piezolyte and cryoprotectant: its role in a depth limit for marine fishes and loss from hadal fish during capture
Published 2025“…<p dir="ltr"><b>I</b><b>NTRODUCTION</b></p><p dir="ltr">Trimethylamine N-oxide (TMAO) is a small organic molecule found at osmotically-significant concentrations in many marine animal taxa. …”
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523
Data Sheet 1_Effects of Th1/Th17 and Th2 cytokines on lipid metabolism in differentiated keratinocytes.zip
Published 2025“…</p>Conclusion<p>The different effects exerted by Th1/Th17 and Th2 cytokines support, at least in part, the features of lipid barrier alterations specific to psoriasis or atopic dermatitis.…”
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524
Additional file 1 of MDM2-amplified esophageal adenocarcinomas exhibit an activated metabolic and immunosuppressive phenotype with multiple potential therapeutic targets
Published 2025“…Volcano plot of all detected proteins comparing the proteome of neoadjuvantly treated MDM2-amplified and non-amplified tumors. Grey: not significantly different expressed, blue: significantly decreased expression in neoadjuvantly treated MDM2-amplified tumors, red: significantly increased expression in neoadjuvantly treated MDM2-amplified tumors. …”
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525
Image 1_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff
Published 2025“…</p>Conclusion<p>This study provides novel evidence that part of the E2-induced enhanced anti-viral response is mediated by increased B cell antibody responses that requires IL-17. …”
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526
Data Sheet 1_α-Mangostin prevents diabetic cardiomyopathy by inhibiting oxidative damage and lipotoxicity through the AKT–FOXO1–CD36 pathway.pdf
Published 2025“…Oxidative stress and lipid metabolism disorder-induced myocardial cell damage are part of the pathogenesis of DCM. In this study, we investigated the effects of alpha-mangostin (A-MG), a natural antioxidant extracted from mangosteen peel, on in vitro and in vivo DCM models.…”
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527
Image 2_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff
Published 2025“…</p>Conclusion<p>This study provides novel evidence that part of the E2-induced enhanced anti-viral response is mediated by increased B cell antibody responses that requires IL-17. …”
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528
Image 5_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff
Published 2025“…</p>Conclusion<p>This study provides novel evidence that part of the E2-induced enhanced anti-viral response is mediated by increased B cell antibody responses that requires IL-17. …”
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529
Image 3_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff
Published 2025“…</p>Conclusion<p>This study provides novel evidence that part of the E2-induced enhanced anti-viral response is mediated by increased B cell antibody responses that requires IL-17. …”
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530
Image 4_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff
Published 2025“…</p>Conclusion<p>This study provides novel evidence that part of the E2-induced enhanced anti-viral response is mediated by increased B cell antibody responses that requires IL-17. …”
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531
The Effect of Chronic Stress on Apoptosis Regulation and Oncogenesis Evolution: A Theoretical Approach.
Published 2025“…At the same time, the importance of a holistic approach to oncological care, including the management of psychological burden as part of the overall cancer treatment strategy, is emphasized. …”
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532
IntegraBrain: A multi-modal neural interface for the detection and suppression of focal epilepsy
Published 2025“…Long-term implantation of these devices would risk inducing significant compression injury and localised glial scaring over time.…”
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533
<b>Dietary Acid Load and Body Weight in Type 1 Diabetes: A Randomized Clinical Trial</b>
Published 2025“…Potential renal acid load and net endogenous acid production—both markers of dietary acid load—decreased significantly in the vegan group, but not in the portion-controlled group. …”
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534
Data for the paper: Physiological responses to ultra-high CO<sub>2</sub> levels in an evergreen tree species
Published 2025“…Photosynthesis significantly increased at 6000 ppm. In summary, ultra-high CO<sub>2</sub> may partly compensate for limited water availability.…”
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535
Table 4_Global, region and country burden of osteoarthritis at different sites in middle-aged and elderly populations from 1990 to 2021: a systematic analysis of the 2021 global bu...
Published 2025“…From 1990 to 2021, the inequality in overall OA burden between countries had decreased. The absolute inequality gap for hand OA had narrowed the most significantly (45.3%), which followed by knee OA (11.9%), while the inequality gap for hip OA has slightly increased.…”
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536
Table 3_Global, region and country burden of osteoarthritis at different sites in middle-aged and elderly populations from 1990 to 2021: a systematic analysis of the 2021 global bu...
Published 2025“…From 1990 to 2021, the inequality in overall OA burden between countries had decreased. The absolute inequality gap for hand OA had narrowed the most significantly (45.3%), which followed by knee OA (11.9%), while the inequality gap for hip OA has slightly increased.…”
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537
Table 1_Global, region and country burden of osteoarthritis at different sites in middle-aged and elderly populations from 1990 to 2021: a systematic analysis of the 2021 global bu...
Published 2025“…From 1990 to 2021, the inequality in overall OA burden between countries had decreased. The absolute inequality gap for hand OA had narrowed the most significantly (45.3%), which followed by knee OA (11.9%), while the inequality gap for hip OA has slightly increased.…”
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538
Table 5_Global, region and country burden of osteoarthritis at different sites in middle-aged and elderly populations from 1990 to 2021: a systematic analysis of the 2021 global bu...
Published 2025“…From 1990 to 2021, the inequality in overall OA burden between countries had decreased. The absolute inequality gap for hand OA had narrowed the most significantly (45.3%), which followed by knee OA (11.9%), while the inequality gap for hip OA has slightly increased.…”
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539
Table 2_Global, region and country burden of osteoarthritis at different sites in middle-aged and elderly populations from 1990 to 2021: a systematic analysis of the 2021 global bu...
Published 2025“…From 1990 to 2021, the inequality in overall OA burden between countries had decreased. The absolute inequality gap for hand OA had narrowed the most significantly (45.3%), which followed by knee OA (11.9%), while the inequality gap for hip OA has slightly increased.…”
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540
Table1_The interaction between selenium and other elements in soil and rice roots shaped by straw and straw biochar regulated the enrichment of selenium in rice grain.docx
Published 2024“…However, the contents of Se in the leaves decreased. Variation partitioning analysis (VPA) indicated that the migration of Se in rice plants was significantly influenced by differences in rice tissues and their interactions with other nutrients [nitrogen (N), phosphorus (P), potassium (K), and Se], explaining 51.5% and 35.3% of the variations in Se content in different rice parts, respectively. …”