Lys823 in NLRP3 is essential for its K27-linked ubiquitination and autophagic degradation. by Huaji Jiang (16907514)

VANGL2 specifically inhibits the activation of NLRP3 inflammasome. by Huaji Jiang (16907514)

VANGL2 recruits NLRP3 to OPTN for selective autophagic degradation. by Huaji Jiang (16907514)

VANGL2 recruits MARCH8 to promote the K27-linked ubiquitination of NLRP3. by Huaji Jiang (16907514)

Expression of Caspase-3 in HCT 116 and Hep 3B: <i>2A. and 2B.</i> by Vidya G. Bettada (22208808)

Thioflavin-T (ThT) fluorescence analysis of amyloid fibril formation in wild-type and p.R163C mutant αB-crystallin under thermochemical stress. by Aref Baharvand (21713886)

Synthesis and Biological Evaluation of MEK/mTOR Multifunctional Inhibitors as Novel Anticancer Agents by Marcian E. Van Dort (21374093)

“…Additionally, compound LP-65 demonstrated significant modulation of MEK and mTOR signaling activity in human glioma cells (D54) and human melanoma cells (A375), with a corresponding decrease in cellular proliferation and migration. …”

Study Data. by Jonathan S. Jahr (2709088)

“…It has also been hypothesized that the bradycardia and rare instances of cardiac arrest occurring after the use of sugammadex may be due to a transient decrease in circulating corticosteroids, causing a temporary ‘mini Addisonian crisis.’ …”

Risk of bias summary. by Duc Tran Quang (20564967)

“…The observed decrease in body weight could be partially attributed to factors influencing energy balance, as evidenced by the significantly lower mean calorie intake at the end of the intervention (1694.71 kcal/day, 95% CI: 1498.57–1890.85) compared to the baseline intake (2000.64 kcal/day, 95% CI: 1830–2172.98), despite the absence of intentional efforts to restrict energy intake by the participants. …”

Study outcomes. by Jonathan S. Jahr (2709088)

“…It has also been hypothesized that the bradycardia and rare instances of cardiac arrest occurring after the use of sugammadex may be due to a transient decrease in circulating corticosteroids, causing a temporary ‘mini Addisonian crisis.’ …”

Criteria for study selection. by Duc Tran Quang (20564967)

“…The observed decrease in body weight could be partially attributed to factors influencing energy balance, as evidenced by the significantly lower mean calorie intake at the end of the intervention (1694.71 kcal/day, 95% CI: 1498.57–1890.85) compared to the baseline intake (2000.64 kcal/day, 95% CI: 1830–2172.98), despite the absence of intentional efforts to restrict energy intake by the participants. …”

Number of visits per clinic type, 2013-2015. by Jacob Dreiher (14856863)

“…During PE, statistically significant longer waiting times were found for surgery (+1.0 day) and imaging (+1.1 days), while a 2.4 days decrease was noted in pediatrics, controlled for age, sex, ethnicity and the daily number of visits. …”

Patient characteristics. by Jonathan S. Jahr (2709088)

“…It has also been hypothesized that the bradycardia and rare instances of cardiac arrest occurring after the use of sugammadex may be due to a transient decrease in circulating corticosteroids, causing a temporary ‘mini Addisonian crisis.’ …”

Feeding and starvation affect the proportion and cell cycle activity of Vasa2+/Piwi1+ cells. by Eudald Pascual-Carreras (12115380)

Changes in the active H3K27ac and repressive H3K27me3 histone marks among Vasa2+/Piwi1+ and all cells in fed, starved, and refed juvenile polyps. by Eudald Pascual-Carreras (12115380)

“…Between fed, T_5ds and T_20ds timepoints, MFI levels of H3K27ac progressively and significantly decreased while levels H3K27me3 (M) did not change significantly (N). …”

The effect of feeding and starvation on the proliferative competence and onset of cell cycle re-entry in all cell cycle-gated cells. by Eudald Pascual-Carreras (12115380)

The TOR inhibitors Rapamycin and AZD-8055 strongly reduce RPS6 phosphorylation and cell proliferation in Vasa2+/Piwi1+ cells. by Eudald Pascual-Carreras (12115380)

“…<i>n</i> = 2–4 biological replicates per condition, with 15 individuals per replicate. Significance levels for Student <i>t</i> test are indicated for adjusted <i>p</i> values: *<i>p</i> < 0.05, ***<i>p</i> < 0.001, ***<i>p</i> < 0.0001. d: day(s), n.s.: non-significant. …”

The effect of feeding and starvation on the proliferative competence and cell cycle re-entry dynamics of Vasa2+/Piwi1+ cells. by Eudald Pascual-Carreras (12115380)

Testing set error. by Xiangjuan Liu (618000)

“…First, seven benchmark models including Prophet, ARIMA, and LSTM were applied to raw price series, where results demonstrated that deep learning models significantly outperformed traditional methods. Subsequently, STL decomposition decoupled the series into trend, seasonal, and residual components for component-specific modeling, achieving a 22.6% reduction in average MAE compared to raw data modeling. …”

Internal structure of an LSTM cell. by Xiangjuan Liu (618000)

“…First, seven benchmark models including Prophet, ARIMA, and LSTM were applied to raw price series, where results demonstrated that deep learning models significantly outperformed traditional methods. Subsequently, STL decomposition decoupled the series into trend, seasonal, and residual components for component-specific modeling, achieving a 22.6% reduction in average MAE compared to raw data modeling. …”