يعرض 21,061 - 21,080 نتائج من 21,342 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant positive decrease ))', وقت الاستعلام: 0.56s تنقيح النتائج
  1. 21061

    Table 1_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.xlsx حسب Rong Su (2210740)

    منشور في 2025
    "…In vitro, the overexpression of miR-4739 in Huh-7 cells significantly induced SPP1<sup>+</sup> macrophages, and the culture medium derived from SPP1<sup>+</sup> macrophages further promoted the proliferation and migration of Huh-7 cells. …"
  2. 21062

    Figure 6 from Distant Metastases of Breast Cancer Resemble Primary Tumors in Cancer Cell Composition but Differ in Immune Cell Phenotypes حسب Laura Kuett (20493991)

    منشور في 2025
    "…<b>F</b> and <b>G,</b> Immune cell phenotypic cluster enrichment in each clinical breast cancer subtype (<b>F</b>) or metastasis-defined patient group (<b>G</b>) at metastatic sites compared with average metastasis composition by differential abundance testing. Circles display significantly enriched (red) or decreased (blue; FDR < 0.05; multiple testing correction with the Benjamin–Hochberg method) results, with size indicating the log-transformed fold change.  …"
  3. 21063

    Supplementary file 1_Single-cell and bulk transcriptomic analyses reveal PANoptosis-associated immune dysregulation of fibroblasts in periodontitis.zip حسب Erli Wu (17785482)

    منشور في 2025
    "…</p>Results<p>scRNA-seq analysis revealed a decreased proportion of HGFs alongside enrichment of multiple PANoptosis-related pathways in PD samples. …"
  4. 21064

    DataSheet2_DYNLT3 overexpression induces apoptosis and inhibits cell growth and migration via inhibition of the Wnt pathway and EMT in cervical cancer.pdf حسب Jianan Zhang (786459)

    منشور في 2025
    "…Up-regulation of DYNLT3 expression significantly inhibited tumor growth in a nude mouse model, while downregulation of DYNLT3 showed the opposite results. …"
  5. 21065

    DNA damage protecting effects of PEExCC. حسب Srabonti Saha (17452756)

    منشور في 2025
    "…The results demonstrated that higher doses (200 mg) of <i>C. chinense</i> methanol extract inhibited immune responses, whereas lower doses helped restore them. The extracts significantly decreased pro-inflammatory mediators and cytokines in LPS-activated macrophages. …"
  6. 21066

    Supplementary file 1_Oral bacterial community dynamics during induction of gingival inflammation.docx حسب Bart J. F. Keijser (16884185)

    منشور في 2025
    "…</p>Results<p>The study revealed pronounced microbial changes, particularly in supragingival plaque, where Leptotrichia and Prevotella increased while Streptococcus decreased. Alpha diversity significantly increased in supragingival plaque, tongue, and saliva during gingivitis induction, highlighting shifts in microbial complexity. …"
  7. 21067

    Table 3_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx حسب Jingjing Chen (293564)

    منشور في 2025
    "…</p>Results<p>We identified 25 ribosome biogenesis-related differentially expressed genes, which were significantly enriched in RNA degradation and rRNA processing. …"
  8. 21068

    Table 1_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.docx حسب Jing Wang (6206297)

    منشور في 2025
    "…</p>Results<p>We found that, in addition to ACTR3C, 17 ARPs were significantly overexpressed in HCC compared with normal tissues. …"
  9. 21069

    <i>Salmonella </i>Typhimurium <i>StiP</i>-mediated upregulation of membrane protein Alx drives complement evasion via CFI-dependent C3b degradation حسب jin guan (21792620)

    منشور في 2025
    "…Invasive strains exhibited significantly enhanced serum resistance (>17-fold survival in 75% isolates) and HeLa cell invasive ability (minimum bacterial loads 3.93 × 10⁵ CFU/mL) compared to non-invasive strains (< 9.8-fold survival; maximum bacterial loads 1.47 × 10⁵ CFU/mL). …"
  10. 21070

    Flexible Microfluidic Devices for Tunable Formation of Double Emulsion حسب Uditha Roshan (20841937)

    منشور في 2025
    "…This innovative approach significantly advances the field of droplet-based microfluidics, providing on-site, real-time tunability for the generation of double-emulsion droplets with high precision and reproducibility.…"
  11. 21071

    Image 5_Establishment and validation of survival nomogram score staging for esophageal squamous cell carcinoma patients after minimally invasive surgery combined with immune progno... حسب Shao-jun Xu (11633956)

    منشور في 2025
    "…Accordingly, we developed the SNS staging and found that the OS and DFS were significantly different among patients at different stages (all P < 0.001). …"
  12. 21072

    Table 1_Moderating effects of a healthy lifestyle on the association of pre-metabolic syndrome with multiple chronic disease comorbidities.docx حسب Youqiong Xu (18161893)

    منشور في 2025
    "…PreMetS [OR = 1.38, 95%CI: 1.16–1.64] and MetS [OR = 1.61, 95%CI: 1.32–1.97] were associated with a significantly higher risk of multiple comorbidities compared with the normal population, and the risk of multiple comorbidities tended to increase as the number of metabolic disorder components increased (p < 0.001). …"
  13. 21073

    Data Sheet 1_Dietary resveratrol and β-Hydroxy-β-Methylbutyric acid enhance flavor and modulate intramuscular fat in Tibetan sheep: insights from transcriptomics and lipidomics.zip... حسب Xuan Chen (158617)

    منشور في 2025
    "…Among medium- and long-chain fatty acids, the H-RES-HMB group showed significantly decreased SFAs (C17:0 and C18:0) (p < 0.05) and significantly increased MUFAs (C15:1N5 and C18:1N9) and PUFAs (C18:2N6, C18:3N6, C18:3N3, C20:3N6, and C20:3N3) (p < 0.05). …"
  14. 21074

    Table 4_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx حسب Leyi Wang (408009)

    منشور في 2025
    "…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4<sup>+</sup>CD38<sup>+</sup>T%, CD8<sup>+</sup>CD38<sup>+</sup>T%, CD155<sup>+</sup>T%, CD4<sup>+</sup>TeM<sup>+</sup>T%, CD8<sup>+</sup>TIGIT<sup>+</sup>T%, and M-MDSC, and decreased CD4<sup>+</sup>LAG3<sup>+</sup>T%, CD4<sup>+</sup>TN<sup>+</sup>T%, and Th17 cells. …"
  15. 21075

    Table 2_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx حسب Leyi Wang (408009)

    منشور في 2025
    "…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4<sup>+</sup>CD38<sup>+</sup>T%, CD8<sup>+</sup>CD38<sup>+</sup>T%, CD155<sup>+</sup>T%, CD4<sup>+</sup>TeM<sup>+</sup>T%, CD8<sup>+</sup>TIGIT<sup>+</sup>T%, and M-MDSC, and decreased CD4<sup>+</sup>LAG3<sup>+</sup>T%, CD4<sup>+</sup>TN<sup>+</sup>T%, and Th17 cells. …"
  16. 21076

    Table 5_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx حسب Leyi Wang (408009)

    منشور في 2025
    "…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4<sup>+</sup>CD38<sup>+</sup>T%, CD8<sup>+</sup>CD38<sup>+</sup>T%, CD155<sup>+</sup>T%, CD4<sup>+</sup>TeM<sup>+</sup>T%, CD8<sup>+</sup>TIGIT<sup>+</sup>T%, and M-MDSC, and decreased CD4<sup>+</sup>LAG3<sup>+</sup>T%, CD4<sup>+</sup>TN<sup>+</sup>T%, and Th17 cells. …"
  17. 21077

    Table 6_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx حسب Leyi Wang (408009)

    منشور في 2025
    "…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4<sup>+</sup>CD38<sup>+</sup>T%, CD8<sup>+</sup>CD38<sup>+</sup>T%, CD155<sup>+</sup>T%, CD4<sup>+</sup>TeM<sup>+</sup>T%, CD8<sup>+</sup>TIGIT<sup>+</sup>T%, and M-MDSC, and decreased CD4<sup>+</sup>LAG3<sup>+</sup>T%, CD4<sup>+</sup>TN<sup>+</sup>T%, and Th17 cells. …"
  18. 21078

    Table 1_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx حسب Leyi Wang (408009)

    منشور في 2025
    "…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4<sup>+</sup>CD38<sup>+</sup>T%, CD8<sup>+</sup>CD38<sup>+</sup>T%, CD155<sup>+</sup>T%, CD4<sup>+</sup>TeM<sup>+</sup>T%, CD8<sup>+</sup>TIGIT<sup>+</sup>T%, and M-MDSC, and decreased CD4<sup>+</sup>LAG3<sup>+</sup>T%, CD4<sup>+</sup>TN<sup>+</sup>T%, and Th17 cells. …"
  19. 21079

    Table 3_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx حسب Leyi Wang (408009)

    منشور في 2025
    "…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4<sup>+</sup>CD38<sup>+</sup>T%, CD8<sup>+</sup>CD38<sup>+</sup>T%, CD155<sup>+</sup>T%, CD4<sup>+</sup>TeM<sup>+</sup>T%, CD8<sup>+</sup>TIGIT<sup>+</sup>T%, and M-MDSC, and decreased CD4<sup>+</sup>LAG3<sup>+</sup>T%, CD4<sup>+</sup>TN<sup>+</sup>T%, and Th17 cells. …"
  20. 21080

    Table1_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.docx حسب Adam D. Price (19842741)

    منشور في 2024
    "…Finally, among septic patients, decreased total TNF and IFNγ expression were associated with 180-day mortality.…"