بدائل البحث:
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
positive decrease » positive breast (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
positive decrease » positive breast (توسيع البحث)
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2061
Image 4_Inhibitior of Bcl6 by FX1 protects DSS induced colitis mice through anti-inflammatory effects.pdf
منشور في 2025"…</p>Results<p>In the treat group, colitis symptoms in mice were significantly improved, and there was a decrease in proportion of macrophages and protection of intestinal mucosal integrity-indicating anti-inflammatory effects of FX1. …"
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2062
Ganaxolone: A Review in Epileptic Seizures Associated with Cyclin‑Dependent Kinase‑Like 5 Deficiency Disorder
منشور في 2024"…</p> <p>Abstract</p> <p>Oral ganaxolone (ZTALMY<sup>®</sup>), a synthetic analogue of the endogenous neuroactive steroid allopregnanolone, acts as a positive allosteric modulator of synaptic and extra-synaptic γ-aminobutyric acid (GABA) type A receptor function in the CNS. …"
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2063
SEAwise Report on improved predictive models of growth, production and stock quality under different habitat scenarios and incorporating experimental results
منشور في 2025"…The third study in the Western Waters analysed relative condition factor in the Bay of Biscay and the Celtic Sea and found significantly decrease over time for 12 species, while two species showed an increase, and three species showed no significant trends. …"
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2064
Table 1_HIF1A acts as target of XiHuang Pill in the treatment of papillary thyroid cancer by regulating dedifferentiation.xlsx
منشور في 2025"…HIF1A upregulation also correlated with the decrease of activated NK cells abundance in PTC (all P < 0.05), while NK cell abundance showed positive correlation with differentiation level (P < 0.05). …"
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2065
Image 1_HIF1A acts as target of XiHuang Pill in the treatment of papillary thyroid cancer by regulating dedifferentiation.tif
منشور في 2025"…HIF1A upregulation also correlated with the decrease of activated NK cells abundance in PTC (all P < 0.05), while NK cell abundance showed positive correlation with differentiation level (P < 0.05). …"
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2066
Table 3_Effects of extracorporeal carbon dioxide removal in facilitating ultra-protective ventilation strategies for patients with acute respiratory distress syndrome: a systematic...
منشور في 2025"…ECCO<sub>2</sub>R significantly reduced driving pressure (weighted mean difference [WMD]: −3.70 cmH<sub>2</sub>O; 95% CI: −4.05 to −3.34; P < 0.001), plateau pressure (WMD: −3.26 cmH<sub>2</sub>O; 95% CI: −3.70 to −2.82; P < 0.001), and tidal volume (WMD: −1.68 mL/kg; 95% CI: −1.81 to −1.55; P < 0.001) at 24 h, while it increased positive end-expiratory pressure (WMD: 0.64 cmH<sub>2</sub>O; 95% CI: 0.44 to 0.85; P < 0.001). …"
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2067
Data Sheet 1_Cynaroside ameliorates TNBS-induced colitis by inhibiting intestinal epithelial cell apoptosis via the PI3K/AKT signalling pathway.pdf
منشور في 2025"…Combining network pharmacology prediction analysis with our validation data from animal models and colonic organoids, we demonstrated that Cyn significantly inhibits IEC apoptosis, as indicated by a decrease in the proportion of TUNEL-positive cells and changes in apoptosis-related protein levels. …"
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2068
Table 1_Effects of extracorporeal carbon dioxide removal in facilitating ultra-protective ventilation strategies for patients with acute respiratory distress syndrome: a systematic...
منشور في 2025"…ECCO<sub>2</sub>R significantly reduced driving pressure (weighted mean difference [WMD]: −3.70 cmH<sub>2</sub>O; 95% CI: −4.05 to −3.34; P < 0.001), plateau pressure (WMD: −3.26 cmH<sub>2</sub>O; 95% CI: −3.70 to −2.82; P < 0.001), and tidal volume (WMD: −1.68 mL/kg; 95% CI: −1.81 to −1.55; P < 0.001) at 24 h, while it increased positive end-expiratory pressure (WMD: 0.64 cmH<sub>2</sub>O; 95% CI: 0.44 to 0.85; P < 0.001). …"
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2069
Table 2_Effects of extracorporeal carbon dioxide removal in facilitating ultra-protective ventilation strategies for patients with acute respiratory distress syndrome: a systematic...
منشور في 2025"…ECCO<sub>2</sub>R significantly reduced driving pressure (weighted mean difference [WMD]: −3.70 cmH<sub>2</sub>O; 95% CI: −4.05 to −3.34; P < 0.001), plateau pressure (WMD: −3.26 cmH<sub>2</sub>O; 95% CI: −3.70 to −2.82; P < 0.001), and tidal volume (WMD: −1.68 mL/kg; 95% CI: −1.81 to −1.55; P < 0.001) at 24 h, while it increased positive end-expiratory pressure (WMD: 0.64 cmH<sub>2</sub>O; 95% CI: 0.44 to 0.85; P < 0.001). …"
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2070
Table 4_Effects of extracorporeal carbon dioxide removal in facilitating ultra-protective ventilation strategies for patients with acute respiratory distress syndrome: a systematic...
منشور في 2025"…ECCO<sub>2</sub>R significantly reduced driving pressure (weighted mean difference [WMD]: −3.70 cmH<sub>2</sub>O; 95% CI: −4.05 to −3.34; P < 0.001), plateau pressure (WMD: −3.26 cmH<sub>2</sub>O; 95% CI: −3.70 to −2.82; P < 0.001), and tidal volume (WMD: −1.68 mL/kg; 95% CI: −1.81 to −1.55; P < 0.001) at 24 h, while it increased positive end-expiratory pressure (WMD: 0.64 cmH<sub>2</sub>O; 95% CI: 0.44 to 0.85; P < 0.001). …"
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2071
CoA administration prevents ISC dysfunction through antioxidative ability and protects ISCs from stress-induced DNA damage.
منشور في 2025"…Asterisks denote levels of significance: *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, and ns (not statistically significant) signifies p > 0.05. …"
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2072
Table 5_Effects of extracorporeal carbon dioxide removal in facilitating ultra-protective ventilation strategies for patients with acute respiratory distress syndrome: a systematic...
منشور في 2025"…ECCO<sub>2</sub>R significantly reduced driving pressure (weighted mean difference [WMD]: −3.70 cmH<sub>2</sub>O; 95% CI: −4.05 to −3.34; P < 0.001), plateau pressure (WMD: −3.26 cmH<sub>2</sub>O; 95% CI: −3.70 to −2.82; P < 0.001), and tidal volume (WMD: −1.68 mL/kg; 95% CI: −1.81 to −1.55; P < 0.001) at 24 h, while it increased positive end-expiratory pressure (WMD: 0.64 cmH<sub>2</sub>O; 95% CI: 0.44 to 0.85; P < 0.001). …"
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2073
Data_Sheet_1_Subthreshold amyloid deposition, cerebral small vessel disease, and functional brain network disruption in delayed cognitive decline after stroke.docx
منشور في 2024"…Only one decliner was amyloid-positive, yet subthreshold PET standardized uptake value ratios (SUVR) in amyloid-negative decliners inversely correlated with final MMSE scores (rho = −0.67, p = 0.04). …"
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2074
Supplementary file 1_Mitigating salt stress in saline-alkali soils through co-application of superabsorbent carbon-based material and flue gas desulfurization gypsum.docx
منشور في 2025"…The CB+FGD treatment significantly reduced soil TSS, electrical conductivity (EC), and SAR. …"
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2075
Data Sheet 1_N6-methyladenosine RNA landscape in the aged mouse hearts.zip
منشور في 2025"…</p>Results<p>The overall m6A level remained constant; however, the expression of the methyltransferase METTL14 and the demethyltransferase FTO were significantly upregulated in aged hearts. Knockdown of METTL14 alleviated H<sub>2</sub>O<sub>2</sub>-induced senescence phenotypes, as reflected by a reduction in the number of SA-β-gal positive cells and a decrease in p21 expression. …"
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2076
Data Sheet 2_N6-methyladenosine RNA landscape in the aged mouse hearts.zip
منشور في 2025"…</p>Results<p>The overall m6A level remained constant; however, the expression of the methyltransferase METTL14 and the demethyltransferase FTO were significantly upregulated in aged hearts. Knockdown of METTL14 alleviated H<sub>2</sub>O<sub>2</sub>-induced senescence phenotypes, as reflected by a reduction in the number of SA-β-gal positive cells and a decrease in p21 expression. …"
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2077
Data Sheet 3_N6-methyladenosine RNA landscape in the aged mouse hearts.zip
منشور في 2025"…</p>Results<p>The overall m6A level remained constant; however, the expression of the methyltransferase METTL14 and the demethyltransferase FTO were significantly upregulated in aged hearts. Knockdown of METTL14 alleviated H<sub>2</sub>O<sub>2</sub>-induced senescence phenotypes, as reflected by a reduction in the number of SA-β-gal positive cells and a decrease in p21 expression. …"
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2078
Data Sheet 4_N6-methyladenosine RNA landscape in the aged mouse hearts.pdf
منشور في 2025"…</p>Results<p>The overall m6A level remained constant; however, the expression of the methyltransferase METTL14 and the demethyltransferase FTO were significantly upregulated in aged hearts. Knockdown of METTL14 alleviated H<sub>2</sub>O<sub>2</sub>-induced senescence phenotypes, as reflected by a reduction in the number of SA-β-gal positive cells and a decrease in p21 expression. …"
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2079
<b>Prevalence and Correlates of Diabetes Distress in Pregnant Individuals With Preexisting Diabetes: A Cross-Sectional Study</b>
منشور في 2024"…Age ≥35 years of age and higher education levels were significantly associated with scores on the Problem Areas in Diabetes (PAID) scale, which measures diabetes-related emotional distress (decreases of 10.18 and 11.77 points, respectively, P = 0.04). …"
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2080
Data Sheet 1_Perceived protective behavioral changes in Chinese residents post-dynamic zero-COVID policy lifting: a cross-sectional study.docx
منشور في 2024"…Avoiding dining out or gathering with friends had the highest percentage of individuals reporting an increase (71.3%), whereas maintaining a social distance of more than 1 m had the highest percentage of individuals reporting a decrease (17.5%). Regression analysis indicated that age, worry, positive coping, female sex, negative coping, and perceived severity were associated with the overall perceived change in protective behaviors, with worry being the most predictive variable.…"