Figure 2 from mTORC1-Driven Protein Translation Correlates with Clinical Benefit of Capivasertib within a Genetically Preselected Cohort of <i>PIK3CA</i>-Altered Tumors by Constance A. Sobsey (19373550)

“…Node size increases as the <i>P</i>-value decreases. <b>B,</b> Top 20 canonical pathways that are significantly differentially activated between clinical benefit (CB) and no clinical benefit (NCB) groups, based on assessment with Fisher’s exact test in Qiagen IPA. …”

Consort flow diagram of the participants. by Preeyaphorn Songsorn (21799601)

“…During flow incentive spirometry, stroke volume and heart rate significantly increased, while cardiac output significantly decreased compared to volume incentive spirometry and costal breathing exercises with sustained maximal inspiration throughout the 10 breathing cycles.…”

Data Sheet 1_Sodium nitroprusside improves circulatory failure in rabbit acute pulmonary embolism combined with shock model possibly by enhancing NO release and inhibiting TLR4/NF-... by Yuchan Zhou (10928151)

“…Pulmonary angiography showed that the mean pulmonary artery pressure increased significantly and the mean arterial pressure decreased significantly in the model group, which could be reversed by SNP treatment. …”

Table 2_Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice.xlsx by Yulia Dwi Setia (21590591)

“…Maximal parasite accumulation in the proximal colon was observed at 8 dpi in histological examination as well as qPCR. Colon length was significantly shortened at 3 dpi. Goblet cell area significantly reduced at 8 dpi (p < 0.05). …”

Data Sheet 1_Reduced circulating regulatory T cells in primary Sjögren’s syndrome: the contribution of enhanced apoptosis and impaired survival.docx by Yanlin Wang (110566)

“…</p>Results<p>The peripheral abundance of Treg cells from relapsing pSS patients was significantly contracted, especially in patients with high disease activity. …”

Table 1_Alterations in sulcal depth and associated functional connectivity in schizophrenia with auditory verbal hallucinations.docx by Zhenru Guo (21811247)

“…</p>Results<p>Schizophrenia patients with auditory verbal hallucinations exhibited significantly increased sulcal depth in left hemispheric regions including the lingual gyrus, cingulate gyrus, pericalcarine cortex, parahippocampal gyrus, superior frontal gyrus, cuneus, and precuneus, whereas decreased sulcal depth was observed in right hemispheric regions encompassing the superior parietal gyrus, superior frontal gyrus, lingual gyrus, lateral occipital cortex, fusiform gyrus, postcentral gyrus, middle frontal gyrus, precentral gyrus, inferior temporal gyrus, precuneus, and parahippocampal gyrus compared to schizophrenia patients without auditory verbal hallucinations. …”

Table 3_Sodium nitroprusside improves circulatory failure in rabbit acute pulmonary embolism combined with shock model possibly by enhancing NO release and inhibiting TLR4/NF-кB/HI... by Yuchan Zhou (10928151)

“…Pulmonary angiography showed that the mean pulmonary artery pressure increased significantly and the mean arterial pressure decreased significantly in the model group, which could be reversed by SNP treatment. …”

Data Sheet 1_Integrated metabolomics and network pharmacology analysis to reveal the mechanisms of Wenshenyang decoction in the treatment of chronic kidney disease.docx by Zongjiang Zhao (21215822)

“…</p>Significance<p>WSY has multi-component and multi-target properties in the treatment of CKD kidney Yang deficiency syndrome, and its mechanism may be related to anti-inflammatory and anti-fibrotic effects. …”

Supplementary file 1_Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice.pdf by Yulia Dwi Setia (21590591)

“…Maximal parasite accumulation in the proximal colon was observed at 8 dpi in histological examination as well as qPCR. Colon length was significantly shortened at 3 dpi. Goblet cell area significantly reduced at 8 dpi (p < 0.05). …”

Data Sheet 1_Reduction of orexin-expressing neurons and a unique sleep phenotype in the Tg-SwDI mouse model of Alzheimer’s disease.pdf by Yan Wu (70890)

“…The apoptotic cell death marker cleaved caspase-3 immunoreactive (Caspase-3-IR) percentage in orexin-IR neurons was significantly higher in Tg-SwDI mice than in WT controls. …”

The recruitment of Paf1C to the <i>frq</i> ORF is regulated by the WCC activity. by Mengmeng Zhou (9197699)

“…<p>(A) The enrichment of PAF-1 (Left) or RTF-1 (Right) at the <i>frq</i> ORF middle region significantly decreased in <i>wc-2</i>^<i>KO</i> strain at DD14. …”

Data Sheet 1_Biomechanical mechanisms of multidirectional dynamic compensatory muscle fatigue induced by abnormal cervical curvature: a cross-sectional case-control study based on... by Rui Yang (293531)

“…During dynamic activities, muscle fatigue was exacerbated in the abnormal curvature group: during extension, the left UT showed significantly decreased MPF (p < 0.01) and MF (p < 0.05); during flexion, the left SCM exhibited significantly increased MPFs (p < 0.05) and MFs (p < 0.01). …”

Table_1_Differential microbiome features in lake–river systems of Taihu basin in response to water flow disturbance.xlsx by Peng Xiao (172430)

“…Additionally, migration and dispersal rates of microbes in the ET region, along with the impact of dispersal limitations, were significantly higher than in the ST region. High flow disturbances notably reduced microbial niche width and overlap, decreasing the complexity and stability of microbial coexistence networks. …”

Image_1_Differential microbiome features in lake–river systems of Taihu basin in response to water flow disturbance.pdf by Peng Xiao (172430)

“…Additionally, migration and dispersal rates of microbes in the ET region, along with the impact of dispersal limitations, were significantly higher than in the ST region. High flow disturbances notably reduced microbial niche width and overlap, decreasing the complexity and stability of microbial coexistence networks. …”

Table 1_Biomechanical mechanisms of multidirectional dynamic compensatory muscle fatigue induced by abnormal cervical curvature: a cross-sectional case-control study based on surfa... by Rui Yang (293531)

“…During dynamic activities, muscle fatigue was exacerbated in the abnormal curvature group: during extension, the left UT showed significantly decreased MPF (p < 0.01) and MF (p < 0.05); during flexion, the left SCM exhibited significantly increased MPFs (p < 0.05) and MFs (p < 0.01). …”

Data_Sheet_1_Analysis of the global burden of cardiovascular diseases linked to exposure to ambient particulate matter pollution from 1990 to 2019.docx by Binbin Zou (11358315)

“…</p>Conclusion<p>The burden of CVDs linked to PM pollution has grown significantly from 1990 to 2019, with variations across regions and countries, highlighting the need for targeted prevention and pollution management strategies.…”

Mitochondria-Derived Reactive Oxygen Species Regulation of Tardigrade Osmobiosis Revealed by Proteomics of Hypsibius exemplaris by Evan R. Stair (17803878)

“…Finally, inhibition of mitochondrial ROS significantly decreases the rate of osmobiote formation suggesting a regulation of osmobiosis through MRC-derived ROS. …”

Data Sheet 1_Improved myocardial mitochondrial energy metabolism in rats with chronic heart failure by modifying fatty acid oxidation using an extract of sand-fired aconite (Jianch... by Hongtao Zhang (167639)

“…</p>Results<p>SFAS significantly improved cardiac function in CHF rats. …”

Therapeutic efficacy of Clrn1 re-expression in Müller glia depends on expression level. by Hannah J. T. Nonarath (20861735)

“…(*p<0.05, **p<0.01, ***p<0.005, ****p<0.001; Two-way ANOVA; Significance shown compared to wild-type <i>gfap</i>:GFP without light stress). …”

Image 1_Huoxiang Zhengqi dropping pills alleviate exertional heat stroke–induced multiple organ injury through sustaining intestinal homeostasis via regulating MAPK/NF-κB pathway a... by Lei Li (29537)

“…The findings revealed that high-dose HXZQD significantly delayed the onset of EHS, reduced core body temperature elevations, and mitigated multi-organ injury, as evidenced by biochemical markers and histopathological examination. …”