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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
potential decrease » potential defense (Expand Search), potential decline (Expand Search), potentially increased (Expand Search)
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2181
Data Sheet 3_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.pdf
Published 2025“…Among them, the placenta-specific 1 (PLAC1) gene stood out, as its inhibition conferred the greatest protection to target cells from NK cell lysis, while overexpression of PLAC1 significantly increased NK cell degranulation. Importantly, PLAC1 was found to interact with NKAR fusion proteins, including NKG2D, DNAM1 NKp44 and NKp30, suggesting its potential involvement in NK cell function. …”
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2182
Data Sheet 5_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.pdf
Published 2025“…Among them, the placenta-specific 1 (PLAC1) gene stood out, as its inhibition conferred the greatest protection to target cells from NK cell lysis, while overexpression of PLAC1 significantly increased NK cell degranulation. Importantly, PLAC1 was found to interact with NKAR fusion proteins, including NKG2D, DNAM1 NKp44 and NKp30, suggesting its potential involvement in NK cell function. …”
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2183
Table 1_Widely conserved miRNAs in buffalo milk extracellular vesicles survive gastrointestinal digestion and potentially target neural and immunomodulatory contexts.docx
Published 2025“…The prospect offered highlights the potential of milk, through its EV-miRNA fraction, to impact inflammatory responses in the neurodevelopmental processes of the benefiting offspring, and by extension, dairy consumers. …”
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2184
Table 2_Widely conserved miRNAs in buffalo milk extracellular vesicles survive gastrointestinal digestion and potentially target neural and immunomodulatory contexts.docx
Published 2025“…The prospect offered highlights the potential of milk, through its EV-miRNA fraction, to impact inflammatory responses in the neurodevelopmental processes of the benefiting offspring, and by extension, dairy consumers. …”
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2185
Flow chart of research object screening.
Published 2025“…Notably, these associations were significant only in non-cancer populations (testosterone: OR=0.97, P < 0.001; estradiol: OR=1.64, P < 0.001), and generally absent in cancer patients except for older cancer patients (≥60 years) where testosterone maintained a significant negative correlation with ALI (OR=0.96, P = 0.020). …”
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2186
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2187
Data Sheet 2_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.pdf
Published 2025“…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …”
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2188
Data Sheet 1_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.pdf
Published 2025“…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …”
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2189
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2190
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2191
Tryptamine Metabolism and Functionalization in Gut Commensal Bacteria Expand Human Tryptamine Signaling Responses
Published 2025“…Gut microbes secrete specialized small molecules that broadly influence human physiology. Despite their potential significance, the variety of functional small molecules known in the gut is relatively limited. …”
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2192
Image 1_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.pdf
Published 2025“…This study investigated the potential involvement of CHMP4A in the progression of LIHC.…”
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2193
Table 1_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.docx
Published 2025“…This study investigated the potential involvement of CHMP4A in the progression of LIHC.…”
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2194
Table 2_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.docx
Published 2025“…This study investigated the potential involvement of CHMP4A in the progression of LIHC.…”
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2195
Image 2_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.pdf
Published 2025“…This study investigated the potential involvement of CHMP4A in the progression of LIHC.…”
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2196
Data_Sheet_1_A novel chimeric endolysin Cly2v shows potential in treating streptococci-induced bovine mastitis and systemic infections.docx
Published 2024“…In summary, Cly2v possesses significant potential as an alternative antibiotic for the treatment of streptococci-induced bovine mastitis and systemic infections.…”
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2197
Evaluation of Chemical Potentials, Bulk Modulus and Volume Expansion Ratio of Li-Si Alloys with Variety of Li Concentrations Using First-Principles Calculations (Supporting Informa...
Published 2025“…However, in the case of LiSi, which has three different polymorphs, significant variation in the bulk modulus is observed. …”
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2198
Data Sheet 1_Ribosomal protein L9 is a potential therapeutic target for B-ALL through the activation of the p53 signaling pathway.docx
Published 2025“…In this study, we observed a significant upregulation of RPL9 in human B-ALL cells compared to normal B cells, suggesting RPL9’s potential key role in B-ALL progression. …”
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2199
Presentation 1_Acupoint catgut embedding alleviates experimental autoimmune encephalomyelitis by modulating neuroinflammation and potentially inhibiting glia activation through JNK...
Published 2025“…In ACE-treated mice, EAE disease severity was significantly ameliorated, along with improvements in anxiety-like behaviors and reduced inflammation and demyelination. …”
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2200
Data Sheet 1_Research on the effect of LAMP1 in the development and progression of ccRCC and its potential mechanism with LC3C-mediated autophagy.docx
Published 2024“…Additionally, we investigated the impact of VHL, a key gene in renal cancer, and LC3C, an autophagy-related gene, on LAMP1 expression through molecular biology experiments to elucidate the potential underlying mechanism.</p>Results<p>Bioinformatics analysis revealed significant underexpression of LAMP1 in ccRCC (P<0.001), which correlated with poorer prognosis. …”