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significant potential » significant positive (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
potential decrease » potential defense (Expand Search), potential decline (Expand Search), potentially increased (Expand Search)
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5781
Supplementary file 1_Comparative analysis of accuracy and completeness in standardized database generation for complex multilingual lung cancer pathological reports: large language...
Published 2025“…</p>Conclusion<p>The fine-tuned lung cancer LLM outperformed non-chief physicians and general LLMs in accuracy/completeness, significantly reduced medical staff workload (p < 0.001), with future optimization potential despite current limitations.…”
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5782
<b>Combination of isobavachalcone and amphotericin B has antifungal effect against </b><b>Cryptococcus neoformans</b><b>and protects host tissue damage by inhibiting ferroptosis</b...
Published 2025“…The results demonstrated that IBC (4 μg/mL) significantly reduced the minimum inhibitory concentration (MIC) of AmB from 1 μg/mL to 0.25 μg/mL, indicating a fourfold increase in potency. …”
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5783
Table 1_LncRNA NEAT1 promotes epithelial–mesenchymal transition in nasal polyp cells via the miR-199-3p/PAK4 axis.docx
Published 2025“…</p>Results<p>In comparison to controls, NEAT1 expression was significantly elevated in the epithelial tissues of CRSwNP. …”
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5784
Table 2_LncRNA NEAT1 promotes epithelial–mesenchymal transition in nasal polyp cells via the miR-199-3p/PAK4 axis.docx
Published 2025“…</p>Results<p>In comparison to controls, NEAT1 expression was significantly elevated in the epithelial tissues of CRSwNP. …”
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5785
Image 4_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.tif
Published 2025“…These results highlight the potential of RMRMs in predicting the prognosis of HCC.…”
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5786
Image1_Characterization of GABAergic marker expression in prefrontal cortex in dexamethasone induced depression/anxiety model.jpeg
Published 2024“…Background<p>The pivotal responsibility of GABAergic interneurons is inhibitory neurotransmission; in this way, their significance lies in regulating the maintenance of excitation/inhibition (E/I) balance in cortical circuits. …”
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5787
Table 1_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.xlsx
Published 2025“…These results highlight the potential of RMRMs in predicting the prognosis of HCC.…”
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5788
Supplementary file 1_Single-cell and bulk transcriptomic analyses reveal PANoptosis-associated immune dysregulation of fibroblasts in periodontitis.zip
Published 2025“…</p>Results<p>scRNA-seq analysis revealed a decreased proportion of HGFs alongside enrichment of multiple PANoptosis-related pathways in PD samples. …”
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5789
Table 1_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.docx
Published 2025“…</p>Results<p>We found that, in addition to ACTR3C, 17 ARPs were significantly overexpressed in HCC compared with normal tissues. …”
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5790
Image 5_A metagenome-wide association study of gut microbiota in hepatitis B virus-related cirrhosis in northwest China.tif
Published 2025“…These findings highlight the potential of gut microbiome-targeted interventions for regional precision medicine of HBV-LC.…”
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5791
Image 5_Establishment and validation of survival nomogram score staging for esophageal squamous cell carcinoma patients after minimally invasive surgery combined with immune progno...
Published 2025“…Accordingly, we developed the SNS staging and found that the OS and DFS were significantly different among patients at different stages (all P < 0.001). …”
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5792
Glucagon-like peptide-1 receptor agonists, inflammation, and kidney diseases: evidence from Mendelian randomization
Published 2025“…</p> <p>After meta-analyses of both discovery and validation cohorts, genetically proxied GLP1R agonist was found to significantly associated with a decreased risk of diabetic nephropathy (OR = 0.72, 95%CI = 0.54–0.97, <i>p</i> = 0.031) and IgA nephropathy (OR = 0.58, 95%CI = 0.36–0.94, <i>p</i> = 0.027). …”
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5793
Table 1_Xinfeng Capsule inhibits oxidative stress via regulating the PPARγ/ Hmgcs2 signaling pathway in lung tissue of adjuvant arthritis rats.docx
Published 2025“…Furthermore, XFC-containing serum suppressed TGF-β1–induced proliferation of lung fibroblasts, promoted PPARγ expression, and significantly decreased the levels of interleukin-6, tumor necrosis factor-α, reactive oxygen species, nicotinamide adenine dinucleotide phosphate oxidase 4, HMGCS2, collagen type I α 1, collagen type III α 1, and α-smooth muscle actin (P < 0.01). …”
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5794
Database of the impact of temperature on development of Aedes aegypti and Aedes albopictus in Cambodia
Published 2025“…During immature stages, development time decreased at higher temperature (35°C), but mortality was increased. …”
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5795
Table 1_The health burden of disease attributable to low calcium intake: a comprehensive analysis of trends and socioeconomic impacts from 1990 to 2021.docx
Published 2025“…</p>Conclusion<p>DLC significantly increases the incidence of CRC, while its impact on prostate cancer incidence is relatively minor and shows a negative correlation. …”
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5796
Data Sheet 1_Epigallocatechin-3-gallate protects against osteoarthritis-induced chondrocytes dysfunction by regulating PLa2g2a.pdf
Published 2025“…OA model demonstrated that EGCG treatment significantly promoted cartilage repair and increased Pla2g2a expression. …”
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5797
DataSheet1_Identification of common signature genes and pathways underlying the pathogenesis association between nonalcoholic fatty liver disease and heart failure.docx
Published 2024“…Experimental validation indicated unbalanced macrophage polarization in HF and NAFLD mouse models, and the expression of CD163 and CCR1 were significantly down-regulated.</p>Conclusion<p>This study identified M2 polarization impairment characterized by decreased expression of CD163 and CCR1 as a common pathogenic pathway in NAFLD and HF. …”
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5798
Data Sheet 1_Wedelia trilobata-derived biochar mitigates chromium toxicity and improves physiological performance in hydroponically grown Chinese cabbage.docx
Published 2025“…Additionally, the malondialdehyde (MDA) content decreased by 29.66% in roots and 15.98% in shoots. …”
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5799
Risk of bias across 22 included studie.
Published 2024“…</p><p>Results</p><p>A meta-analysis of 22 RCTs (n = 3,463) showed that ketamine/esketamine significantly decreased PPD risk at 1- (risk ratio [RR], 0.41; 95% confidence interval [CI], 0.3–0.57) and 4–6-week (RR, 0.47; 95%CI, 0.35–0.63) follow-ups. …”
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5800
Table 1_Determining the efficacy and safety of acupuncture for the treatment of menstrual migraine: an updated systematic review and meta-analysis.docx
Published 2025“…Compared with control interventions, acupuncture significantly reduced VAS scores, decreased the frequency and duration of migraine attacks, and improved response rates, as well as HIT-6 and MHI scores. …”