يعرض 20,221 - 20,240 نتائج من 21,342 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant processes decrease ))', وقت الاستعلام: 0.39s تنقيح النتائج
  1. 20221

    <b>SZC-6</b><b> Promotes Diabetic Wound Healing in Mice by Modulating M1/M2 Macrophage Ratio and Inhibiting MyD88/NF-κB Pathway</b> حسب 昂 轩 (20139579)

    منشور في 2024
    "…We also found that SZC-6 significantly reduced MyD88, p-IκBα, and p-P65 protein levels and inhibited the nuclear translocation of P65 in LPS-treated cells. …"
  2. 20222

    Supplementary file 1_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.jpeg حسب Yuhui Zhang (399617)

    منشور في 2025
    "…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …"
  3. 20223

    Data Sheet 2_Early boosting of p38 MAPK signaling pathway by lycorine hydrochloride potently inhibits PRRSV proliferation in primary and established cells.pdf حسب Lizhan Su (19936980)

    منشور في 2025
    "…Mechanistically, LH treatment induced a rapid up-regulation of p38 MAPK signaling pathway in both infected and uninfected cells, which enhanced the expressions of NLRP3 and Caspase-1 proteins, thereby promoting the conversion of pro-IL-1β to IL-1β, which led to decreased PRRSV replication. In summary, this study reveals that early boosting of p38 MAPK signaling pathway induced by LH treatment significantly suppresses PRRSV propagation, and LH has the potential to be used as a novel antiviral agent against PRRSV infections.…"
  4. 20224

    Annual system costs and benefits. حسب Kai Wen (261662)

    منشور في 2025
    "…The results show that the system can effectively recover waste heat from the DC, significantly reducing cooling electricity consumption during the heating season and decreasing original heating steam consumption by about 25%. …"
  5. 20225

    Data Sheet 1_Comparative hepatoprotective effects of AMK and PAMK via Nrf2 signaling in broiler breeders.pdf حسب Baili Lu (21192662)

    منشور في 2025
    "…Both AMK and PAMK significantly reduced serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities compared to control. …"
  6. 20226

    Data_Sheet_1_Diffusion and functional MRI reveal microstructural and network connectivity impairment in adult-onset neuronal intranuclear inclusion disease.docx حسب Rui Zhu (305217)

    منشور في 2024
    "…</p>Results<p>Compared with the HCs, NIID patients showed reduced mean kurtosis (MK), radial kurtosis (RK), axial kurtosis (AK), and kurtosis fractional anisotropy (KFA) values in deep gray matter regions. Significantly decreased MK, RK, AK, KFA and fractional anisotropy (FA), and increased mean diffusivity (MD) values were observed in extensive white matter fiber tracts. …"
  7. 20227

    Image 6_Isolation and identification of Alternaria alstroemeriae causing postharvest black rot in citrus and its control using curcumin-loaded nanoliposomes.jpeg حسب Jie Li (15030)

    منشور في 2025
    "…Curcumin-loaded nanoliposomes also enhanced the activities of the enzymes PPO, APX, POD, PAL, GR and CAT of citrus, decreased the O<sub>2</sub><sup>−</sup> production rate. …"
  8. 20228

    <b>Glucose</b><b>-6-Phosphatase Catalytic Subunit 3 Enhances Host Resistance to Porcine Epidemic Diarrhea Virus Through Regulating </b><b>Glycolysis/Gluconeogenesis</b> حسب Huihui Li (22299664)

    منشور في 2025
    "…Notably, Glucose-6-Phosphatase Catalytic Subunit 3 (<i>G6PC3</i>) expression was significantly higher in Chinese Min piglets than in Yorkshire piglets. …"
  9. 20229

    Image 2_Resveratrol and β-hydroxy-β-methylbutyric acid supplementation promotes ileal development and digestive function by altering microbial community abundance and metabolites i... حسب Jiacheng Gan (20413847)

    منشور في 2024
    "…</p>Results<p>Results indicated that dietary RES and (or) HMB supplementation significantly improved the phenotype (mucosal thickness and villus width), SCFAs concentrations, and digestive enzymes (lipase, cellulase, and α-amylase) (p < 0.05). …"
  10. 20230

    Uncropped western blot images. حسب Tingting Jiang (169999)

    منشور في 2025
    "…Functional assays demonstrated that targeted repression of Pparα-En4 region significantly decreased <i><i>Ppar</i>α</i> expression and impaired brown adipocyte differentiation and thermogenesis. …"
  11. 20231

    Supplementary Material for: Endoscopic Anti-reflux Mucosal Interventions for Gastroesophageal Reflux Disease: A Systematic Review and Meta-Analysis of Efficacy, Safety, and Compara... حسب figshare admin karger (2628495)

    منشور في 2025
    "…AET decreased at 3–6 months (P<0.001). Overall AEs occurred in 13% of cases (bleeding: 3%; stricture: 8%; dysphagia: 8%). …"
  12. 20232

    Different types of participants have different responses to exposure to new normative environments: Judgment changes. حسب Claire Lugrin (21156528)

    منشور في 2025
    "…The patterns and magnitude of parameter changes are similar for the different clusters within each normative environment, although some parameter changes are below significance.</p> <p>(TIF)</p>…"
  13. 20233

    Real-time PCR primer sequences. حسب Hyerim Park (303433)

    منشور في 2025
    "…Compared to mice on the P-MAL diet alone, Lp<sup>WJL</sup> supplementation significantly increased muscle mass and size, resulting in enhanced muscle strength and endurance capacity. …"
  14. 20234

    Raw data of this work. حسب Ming Liu (105953)

    منشور في 2024
    "…At the individual level, baseline positive identity and general positive youth development significantly increased persistent non-depression at T2 and T3. …"
  15. 20235

    Image 1_Isolation and identification of Alternaria alstroemeriae causing postharvest black rot in citrus and its control using curcumin-loaded nanoliposomes.jpeg حسب Jie Li (15030)

    منشور في 2025
    "…Curcumin-loaded nanoliposomes also enhanced the activities of the enzymes PPO, APX, POD, PAL, GR and CAT of citrus, decreased the O<sub>2</sub><sup>−</sup> production rate. …"
  16. 20236

    Image 1_Unraveling impact and potential mechanisms of baseline pain on efficacy of immunotherapy in lung cancer patients: a retrospective and bioinformatic analysis.jpg حسب Zexin Zhang (7507979)

    منشور في 2024
    "…ELISA assay results indicated that the level of CXCL12 significantly decreased compared to baseline after pain was relieved.…"
  17. 20237

    Image 10_Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.jpeg حسب Dang Li (16400478)

    منشور في 2024
    "…<p>Keloid scarring is a fibroproliferative disease of the skin, which can significantly impact one’s quality of life through cosmetic concerns, physical discomfort (itchy; painful), restricted movement, and psychological distress. …"
  18. 20238

    Profile of the respondents. حسب Şehrinaz Polat (20978625)

    منشور في 2025
    "…Experiencing a career plateau can result in negative work outcomes, including decreased job satisfaction and reduced motivation. …"
  19. 20239

    <b>The Mediating Role of Mental Fatigue Awareness in the Relationship Between Perceived Stress and Psychological Well-Being Among Combat Athletes</b> حسب coşkun yılmaz (21505391)

    منشور في 2025
    "…</b>Perceived stress significantly increased mental fatigue awareness (b = 0.732 ± 0.064, β = 0.549, p = 0.001) and directly decreased psychological well-being (b = –0.488 ± 0.166, β = –0.191, p = 0.004). …"
  20. 20240

    Image 9_Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.jpeg حسب Dang Li (16400478)

    منشور في 2024
    "…<p>Keloid scarring is a fibroproliferative disease of the skin, which can significantly impact one’s quality of life through cosmetic concerns, physical discomfort (itchy; painful), restricted movement, and psychological distress. …"