Data Sheet 1_Targeting the leptin receptor promotes MDA-MB-231 cells’ metabolic reprogramming and malignancy: the role of extracellular vesicles derived from obese adipose tissue.d... by Carol Costa Encarnação (21412730)

“…This effect was reversed in the presence of a leptin receptor antagonist, highlighting leptin’s pivotal role in these processes. Additionally, OB EVs caused metabolic changes, including reduced lactate levels and decreased pyruvate kinase (PK) activity, while increasing glucose-6-phosphate dehydrogenase (G6PDH) activity, suggesting metabolic reprogramming that supports tumor cell survival and proliferation. …”

Data Sheet 2_Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway.docx by Xin Zhou (54275)

“…</p>Results<p>The proteomic profiling of lung tissues from LPS-challenged mice identified significant dysregulation of proteins integral to the cGAS-STING cascade and pyroptotic processes. …”

Data Sheet 1_Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway.docx by Xin Zhou (54275)

“…</p>Results<p>The proteomic profiling of lung tissues from LPS-challenged mice identified significant dysregulation of proteins integral to the cGAS-STING cascade and pyroptotic processes. …”

Table 1_Reconstructing Holocene centennial cooling events: synthesized temperature changes, chronology, and forcing in the Northern Hemisphere.xlsx by Sergey A. Gorbarenko (13696381)

“…The Holocene Thermal Maximum (HTM) happened between HCCEs 5 and 4a and was interrupted by HCCE 4c and 4b, coeval, with a significant southward shift of the ITCZ, likely related to cooling in the tropical zone. …”

Data Sheet 1_The CD38+HLA-DR+ T cells with activation and exhaustion characteristics as predictors of severity and mortality in COVID-19 patients.docx by Qiuyue Long (11381148)

“…Further functional analysis demonstrated its enhanced major histocompatibility complex class II (MHC-II) cross-signaling and correspondingly enriched cytoskeletal rearrangement processes. In addition, there was dysregulated NAD⁺ metabolism in CD38+HLA-DR+ T cells via scRNA-seq, accompanied by elevated adenosine and decreased NAD⁺ levels in serums from COVID-19 patients.…”

Data Sheet 1_Elevated Galectin-3 levels in the tumor microenvironment of ovarian cancer – implication of ROS mediated suppression of NK cell antitumor response via tumor-associated... by Veronika Karlsson (20457788)

“…Current cancer immunotherapies are not efficient in ovarian cancer, and there is therefore a significant need for novel treatment options. The β-galactoside-binding lectin, Galectin-3, is involved in different immune processes and has been associated with poor outcome in various cancer diagnoses. …”

Data Sheet 1_Reconstructing Holocene centennial cooling events: synthesized temperature changes, chronology, and forcing in the Northern Hemisphere.docx by Sergey A. Gorbarenko (13696381)

“…The Holocene Thermal Maximum (HTM) happened between HCCEs 5 and 4a and was interrupted by HCCE 4c and 4b, coeval, with a significant southward shift of the ITCZ, likely related to cooling in the tropical zone. …”

Data Sheet 1_Investigation on the influence of structural surface characteristics on stress wave propagation behavior.docx by Pengxu Jing (20830229)

“…Furthermore, an increase in the damping ratio further accelerates the energy dissipation process, resulting in a significant reduction in the amplitude of stress waves at the propagation endpoint, which emphasizes the crucial role of damping effects in the attenuation of stress wave energy. …”

Data Sheet 1_Global burden of Type 2 Diabetes Mellitus attributable to dietary risks in elderly adults: insights from the Global Burden of Disease study 2021.docx by Yiting Tang (2295307)

“…Background<p>Type 2 Diabetes Mellitus (T2DM) poses a significant global health challenge, particularly among elderly adults. …”

CARE-checklist JOSPT[1].docx by Sanjivani Bangde (19749151)

“…<p dir="ltr"><b>Background</b>: Elbow stability relies on the bony congruity of the joint, supported by the coronoid process, radial head, and ligaments like lateral ulnar collateral ligament and radial collateral ligament. …”

Data Sheet 1_Patient-centered modeling of the breast biopsy experience.pdf by Isabel Nieto-Alvarez (22425466)

“…Centering each individual's procedure time at her first local anesthesia (LA) revealed a significant (βt2p = 5.43e⁻⁰⁶) temporal pattern in anxiety, which increased until LA and decreased afterwards. …”

Data Sheet 1_Transcriptome analysis of Ipomoea cairica algicidal mechanism against Phaeocystis globosa.docx by Dayong Liang (21083714)

“…The results of physiological experiments showed no difference in the number of solitary cells and colonies at 24 h, but significant decreases at 48 h. Transcriptomic data also showed significant differences in differentially expressed genes (DEGs) at 24 and 48 h. …”

Trivalent chromium ion removal from synthetic wastewater using graphene oxide nanocollector by various flotation mechanisms by Mohammad Sadatipour (20575527)

“…<p>The scarcity of freshwater resources for industrial applications poses a significant global concern. Therefore, wastewater treatment is vital for industrial reuse and decreases environmental damage. …”

Data Sheet 1_Use of HLA desensitization in the management of renal transplant recipients in Europe.pdf by Lionel P. E. Rostaing (22138330)

“…As the degree of sensitization increases, the likelihood of finding a compatible organ decreases. Desensitization is the process of reducing recipient anti-HLA antibodies to acceptable levels to allow transplantation. …”

Visual surround network activation modulates center excitability in the SCs. by Peng Cui (33358)

“…Arrow shows direction of process when neuron is activated. Smaller gray arrow indicates point of center stimulation in the surround-to-center case. …”

Effects of repeated intravenous esketamine administration on affective biases by Christine Reif-Leonhard (20516212)

“…</p> <p>66.7% participants who received at least five infusions (<i>n</i> = 12) showed significant improvement. Emotion recognition improved for all emotions except sadness, where accuracy decreased, particularly for low-intensity expressions (<i>p</i> = .007, d = −1.09). …”

Table 1_Structural and functional alterations in the contralateral hemisphere following pediatric intracranial surgery: a pilot longitudinal neuroimaging study.docx by Na Yan (450205)

“…This process demonstrates progressive and cumulative characteristics. …”

Data Sheet 1_Linarin alleviates colonic barrier dysfunction induced by enterotoxic Escherichia coli in weaned piglets by regulating the gut microbiota and metabolic pathways.docx by Qianqian Zhang (587342)

“…</p>Results<p>Linarin supplementation significantly ameliorated colonic crypt hyperplasia, increased goblet cell numbers, and decreased diarrhea incidence following ETEC infusion. …”

Supplementary materials for PhD thesis - "Understanding ⁴⁰Ar/³⁹Ar age variations in basaltic lavas" by Cramer-Lee Elizabeth (22048359)

“…A criteria for assessing the reliability of an ⁴⁰Ar/³⁹Ar age is proposed to evaluate each ⁴⁰Ar/³⁹Ar age, which has decreased the inter-lava ⁴⁰Ar/³⁹Ar age variability. …”

Supplementary file 1_The effect of 8-week Tai Chi training on emotional regulation in female college students: an ERP study of N2 and P3 under a modified oddball paradigm.docx by Jin Yuan (120922)

“…No significant effects were observed for P3 latency.</p>Conclusion<p>This study demonstrates that 8 weeks of Tai Chi training modulated both neural and behavioral responses to emotional stimuli in healthy female college students, suggesting potential benefits for attentional processes in emotional regulation, though neural-behavioral links require further investigation.…”