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significant processes » significant progress (Expand Search), significant promise (Expand Search), significant increases (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
processes decrease » progressive decrease (Expand Search)
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2241
Table 1_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx
Published 2025“…Furthermore, SSA displayed inhibitory effects on tumor growth with minimal toxicity in animal studies, accompanied by activated biomarkers of cellular senescence and decreased expression of p-Akt and p-PI3K.</p>Conclusion<p>Taken together, based on the preliminary results of network analysis and further experimental validation, this study revealed that SSA significantly induced cell cycle arrest and senescence, and the inhibition of ROS-mediated PI3K/Akt pathway may be the potential mechanism in this process.…”
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2242
Data Sheet 1_Investigation of the physiological and molecular regulatory mechanism of soluble sugar metabolism in Lavandula angustifolia Mill. under cold stress.docx
Published 2025“…The results revealed that when the temperature dropped from 30°C to 0°C, the amylase activities and the content of maltose and glucose increased, while the starch content decreased. During the process, the up-regulation of LaAMY and LaBAM1/3 suggests an adaptive response in L. angustifolia to cold stress by promoting the breakdown of starch. …”
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2243
Exploring cardiac vector propagation in acute myocardial infarction: a spatial velocity perspective
Published 2024“…There was no apparent alteration of SM in AMI.</p> <p>Decreased SV and SD without any significant alteration of SM indicates close approximation and clustering of the tips of the ventricular vector in AMI. …”
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2244
Molecular signatures underlying multisensory gamma stimulation-associated cognitive benefits in the hippocampus.
Published 2025“…Color represents statistical significance after multiple testing adjustments. <b>E)</b> Signed bar plot displaying significant co-expression changes of the identified 7 gene modules in hippocampal excitatory neurons in stimulation vs ambient TsD65n mice. …”
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2245
DataSheet1_Case report: Comprehensive clinical, pathological and genetic investigations to decipher the background of cyclic thrombocytopenia.pdf
Published 2024“…The pathomechanism of the disease is poorly understood, several pathological processes have been implied in the background of CTP. …”
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2246
Dynamic Analysis of Membrane Emulsification: An In Situ Observation and Calculation with Deep Learning Model
Published 2025“…Existing studies lack in situ observation of formation processes, hindering correlation between pore structures and emulsion performance. …”
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2247
Table 8_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx
Published 2025“…The absence of CX3CR1 significantly altered microglial morphology, resulting in enlarged cell bodies and shortened processes in the hippocampus and frontal cortex. …”
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2248
Table 4_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx
Published 2025“…The absence of CX3CR1 significantly altered microglial morphology, resulting in enlarged cell bodies and shortened processes in the hippocampus and frontal cortex. …”
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2249
Table 7_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx
Published 2025“…The absence of CX3CR1 significantly altered microglial morphology, resulting in enlarged cell bodies and shortened processes in the hippocampus and frontal cortex. …”
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2250
Table 10_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx
Published 2025“…The absence of CX3CR1 significantly altered microglial morphology, resulting in enlarged cell bodies and shortened processes in the hippocampus and frontal cortex. …”
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2251
Table 2_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx
Published 2025“…The absence of CX3CR1 significantly altered microglial morphology, resulting in enlarged cell bodies and shortened processes in the hippocampus and frontal cortex. …”
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2252
Table 11_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx
Published 2025“…The absence of CX3CR1 significantly altered microglial morphology, resulting in enlarged cell bodies and shortened processes in the hippocampus and frontal cortex. …”
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2253
Table 1_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx
Published 2025“…The absence of CX3CR1 significantly altered microglial morphology, resulting in enlarged cell bodies and shortened processes in the hippocampus and frontal cortex. …”
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2254
Table 9_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx
Published 2025“…The absence of CX3CR1 significantly altered microglial morphology, resulting in enlarged cell bodies and shortened processes in the hippocampus and frontal cortex. …”
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2255
Table 5_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx
Published 2025“…The absence of CX3CR1 significantly altered microglial morphology, resulting in enlarged cell bodies and shortened processes in the hippocampus and frontal cortex. …”
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2256
Table 3_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx
Published 2025“…The absence of CX3CR1 significantly altered microglial morphology, resulting in enlarged cell bodies and shortened processes in the hippocampus and frontal cortex. …”
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2257
Table 6_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx
Published 2025“…The absence of CX3CR1 significantly altered microglial morphology, resulting in enlarged cell bodies and shortened processes in the hippocampus and frontal cortex. …”
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2258
Data Sheet 1_Non-targeted metabolomics-mediated elucidation of metabolite changes in Polygonatum kingianum during traditional steaming with black beans.zip
Published 2025“…Compared to the raw PK, the P3 stage exhibited significant increases in saponins, total sugars, organic acids, and flavonoids by 21.29, 35.02, 49.13, and 44.76%, respectively (p < 0.05), reducing sugars showed a remarkable increase of 160.94-fold (p < 0.01), while polysaccharides decreased significantly by 43.33% (p < 0.01).…”
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2259
Figure 6 from Membrane-bound Heat Shock Protein mHsp70 Is Required for Migration and Invasion of Brain Tumors
Published 2025“…<p>Inhibition of mHsp70 results in decreased motility of patient-derived brain tumor cells. …”
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2260
Table_4_Between-Subject and Within-Subject Variation of Muscle Atrophy and Bone Loss in Response to Experimental Bed Rest.pdf
Published 2025“…The results showed that U<sub>Meas</sub> decreased 59.3% to 80% over the two decades of bed rest studies (p < 0.01), and that it was higher for muscles than for bones. …”