Data Sheet 2_Triterpenes in breast cancer: a systematic review of preclinical evidence in rodents.xlsx by Alexandra Prodea (22617710)

“…Introduction<p>Breast cancer poses a significant health problem for women worldwide due to late-stage diagnosis, toxicity of standard therapy and drug resistance. …”

Table_6_Between-Subject and Within-Subject Variation of Muscle Atrophy and Bone Loss in Response to Experimental Bed Rest.pdf by Jonas Böcker (12116898)

“…The results showed that U_Meas decreased 59.3% to 80% over the two decades of bed rest studies (p < 0.01), and that it was higher for muscles than for bones. …”

Data Sheet 1_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx by Yingchao Wu (2870927)

“…Furthermore, SSA displayed inhibitory effects on tumor growth with minimal toxicity in animal studies, accompanied by activated biomarkers of cellular senescence and decreased expression of p-Akt and p-PI3K.</p>Conclusion<p>Taken together, based on the preliminary results of network analysis and further experimental validation, this study revealed that SSA significantly induced cell cycle arrest and senescence, and the inhibition of ROS-mediated PI3K/Akt pathway may be the potential mechanism in this process.…”

Data Sheet 4_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.pdf by Yingchao Wu (2870927)

“…Furthermore, SSA displayed inhibitory effects on tumor growth with minimal toxicity in animal studies, accompanied by activated biomarkers of cellular senescence and decreased expression of p-Akt and p-PI3K.</p>Conclusion<p>Taken together, based on the preliminary results of network analysis and further experimental validation, this study revealed that SSA significantly induced cell cycle arrest and senescence, and the inhibition of ROS-mediated PI3K/Akt pathway may be the potential mechanism in this process.…”

Data Sheet 1_Intratumoral and fecal microbiota reveals microbial markers associated with gastric carcinogenesis.docx by Yiwen Wang (666361)

“…Network analysis showed that the positive correlation with GC-enriched bacteria increased, and the positive correlation with GC-depleted bacteria decreased compared to healthy individuals. Functional analyses indicated that pathways related to carbohydrate metabolism were significantly enriched in GC, while biosynthesis of unsaturated fatty acids was diminished. …”

Table 1_Impact of hearing loss on brain signal variability in older adults under different auditory load conditions.docx by Songjian Wang (18173353)

“…In contrast, we found that hearing loss reduced brain signal variability during speech recognition tasks, especially in noisy conditions, in the mild hearing loss and moderate to severe hearing loss groups, possibly indicating decreased neural processing efficiency. Additionally, a positive correlation between brain signal variability and speech recognition performance was observed in healthy control participants across all SNR conditions, suggesting that brain signal variability could dynamically respond to the precise level of auditory environment demands. …”

Image 1_Correlation between hemoglobin-to-albumin ratio and complications after radical gastrectomy in gastric cancer patients.tif by Wenbin Luo (571520)

“…Subgroup analysis showed that most subgroups did not exhibit significant differences in interaction p values. Interestingly, a significant interaction was observed between HAR and platelet (interaction p = 0.011).…”

Data Sheet 3_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx by Yingchao Wu (2870927)

“…Furthermore, SSA displayed inhibitory effects on tumor growth with minimal toxicity in animal studies, accompanied by activated biomarkers of cellular senescence and decreased expression of p-Akt and p-PI3K.</p>Conclusion<p>Taken together, based on the preliminary results of network analysis and further experimental validation, this study revealed that SSA significantly induced cell cycle arrest and senescence, and the inhibition of ROS-mediated PI3K/Akt pathway may be the potential mechanism in this process.…”

Table_3_Between-Subject and Within-Subject Variation of Muscle Atrophy and Bone Loss in Response to Experimental Bed Rest.pdf by Jonas Böcker (12116898)

“…The results showed that U_Meas decreased 59.3% to 80% over the two decades of bed rest studies (p < 0.01), and that it was higher for muscles than for bones. …”

Table_2_Between-Subject and Within-Subject Variation of Muscle Atrophy and Bone Loss in Response to Experimental Bed Rest.pdf by Jonas Böcker (12116898)

“…The results showed that U_Meas decreased 59.3% to 80% over the two decades of bed rest studies (p < 0.01), and that it was higher for muscles than for bones. …”

Table 1_Correlation between hemoglobin-to-albumin ratio and complications after radical gastrectomy in gastric cancer patients.docx by Wenbin Luo (571520)

“…Subgroup analysis showed that most subgroups did not exhibit significant differences in interaction p values. Interestingly, a significant interaction was observed between HAR and platelet (interaction p = 0.011).…”

Data Sheet 1_Triterpenes in breast cancer: a systematic review of preclinical evidence in rodents.pdf by Alexandra Prodea (22617710)

“…Introduction<p>Breast cancer poses a significant health problem for women worldwide due to late-stage diagnosis, toxicity of standard therapy and drug resistance. …”

Data Sheet 2_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx by Yingchao Wu (2870927)

“…Furthermore, SSA displayed inhibitory effects on tumor growth with minimal toxicity in animal studies, accompanied by activated biomarkers of cellular senescence and decreased expression of p-Akt and p-PI3K.</p>Conclusion<p>Taken together, based on the preliminary results of network analysis and further experimental validation, this study revealed that SSA significantly induced cell cycle arrest and senescence, and the inhibition of ROS-mediated PI3K/Akt pathway may be the potential mechanism in this process.…”

Table_5_Between-Subject and Within-Subject Variation of Muscle Atrophy and Bone Loss in Response to Experimental Bed Rest.pdf by Jonas Böcker (12116898)

“…The results showed that U_Meas decreased 59.3% to 80% over the two decades of bed rest studies (p < 0.01), and that it was higher for muscles than for bones. …”

Table_1_Between-Subject and Within-Subject Variation of Muscle Atrophy and Bone Loss in Response to Experimental Bed Rest.pdf by Jonas Böcker (12116898)

“…The results showed that U_Meas decreased 59.3% to 80% over the two decades of bed rest studies (p < 0.01), and that it was higher for muscles than for bones. …”

Data Sheet 1_In vivo quantification of superficial cortical veins on susceptibility-weighted imaging with artificial intelligence image segmentation and the potential mechanism of... by Qi Xie (230608)

“…</p>Results<p>The quantitative value of SCV were significantly greater in males than in females. In higher age groups, the total number of SCVs and the number of SCVs in the left and right cerebral hemispheres significantly decreased. …”

Data Sheet 3_Association between sarcopenia and outcomes of surgically treated oral squamous cell carcinoma: a systematic review and meta‐analysis.pdf by Kai Luo (769190)

“…The one-year OS (OR = 0.71, 95% CI = 0.67-0.75, P < 0.00001) and five-year OS (OR = 0.60, 95% CI = 0.45-0.79, P = 0.0003) decreased significantly. Patients with sarcopenia had significantly increased 30-day postoperative mortality and an also increased risk of pneumonia (OR = 1.36, 95% CI = 1.24-1.49, P < 0.00001) and surgical site infection (OR = 2.49, 95% CI = 1.06-5.84, P = 0.04).…”

Data Sheet 2_Association between sarcopenia and outcomes of surgically treated oral squamous cell carcinoma: a systematic review and meta‐analysis.pdf by Kai Luo (769190)

“…The one-year OS (OR = 0.71, 95% CI = 0.67-0.75, P < 0.00001) and five-year OS (OR = 0.60, 95% CI = 0.45-0.79, P = 0.0003) decreased significantly. Patients with sarcopenia had significantly increased 30-day postoperative mortality and an also increased risk of pneumonia (OR = 1.36, 95% CI = 1.24-1.49, P < 0.00001) and surgical site infection (OR = 2.49, 95% CI = 1.06-5.84, P = 0.04).…”

Table 1_Association between sarcopenia and outcomes of surgically treated oral squamous cell carcinoma: a systematic review and meta‐analysis.docx by Kai Luo (769190)

“…The one-year OS (OR = 0.71, 95% CI = 0.67-0.75, P < 0.00001) and five-year OS (OR = 0.60, 95% CI = 0.45-0.79, P = 0.0003) decreased significantly. Patients with sarcopenia had significantly increased 30-day postoperative mortality and an also increased risk of pneumonia (OR = 1.36, 95% CI = 1.24-1.49, P < 0.00001) and surgical site infection (OR = 2.49, 95% CI = 1.06-5.84, P = 0.04).…”

Data Sheet 1_Association between sarcopenia and outcomes of surgically treated oral squamous cell carcinoma: a systematic review and meta‐analysis.pdf by Kai Luo (769190)

“…The one-year OS (OR = 0.71, 95% CI = 0.67-0.75, P < 0.00001) and five-year OS (OR = 0.60, 95% CI = 0.45-0.79, P = 0.0003) decreased significantly. Patients with sarcopenia had significantly increased 30-day postoperative mortality and an also increased risk of pneumonia (OR = 1.36, 95% CI = 1.24-1.49, P < 0.00001) and surgical site infection (OR = 2.49, 95% CI = 1.06-5.84, P = 0.04).…”