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significant processes » significant progress (Expand Search), significant promise (Expand Search), significant increases (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
processes decrease » progressive decrease (Expand Search)
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2641
Data Sheet 7_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.zip
Published 2025“…Within the IG group, IL-6, JAK2, STAT3, and IL-1β proteins were significantly elevated compared to the HC group, whereas STAT1, p-JAK2, and p-STAT1/3 proteins were significantly lower. …”
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2642
Data Sheet 4_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.zip
Published 2025“…Within the IG group, IL-6, JAK2, STAT3, and IL-1β proteins were significantly elevated compared to the HC group, whereas STAT1, p-JAK2, and p-STAT1/3 proteins were significantly lower. …”
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2643
Data Sheet 1_BMP9 induces postnatal zonal stratification of immature articular cartilage through reconfiguration of the existing collagen framework.pdf
Published 2025“…In explants exposed to BMP9, collagen fibrils underwent angular displacement from 19° to 78° with respect to the surface, cell density decreased 1.77-fold, and chondrons were significantly larger. …”
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2644
Supplementary Material for: Reduction of waste mass in used hemodialysis circuits by QCC activity
Published 2025“…Conclusion: The implementation of QCC activities has significantly reduced residual waste from hemodialysis circuits, leading to environmental conservation and lower waste disposal costs. …”
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2645
Table 1_Has carbon finance been able to promote clean energy development? — a low-carbon technology innovation perspective.xlsx
Published 2025“…Therefore, this study explores the evolution of spatio-temporal dynamics and heterogeneity of the impact of carbon finance on clean energy development using spatial econometric modelling based on panel data from 30 provinces in China from 2010–2023, and also further explores the role of low-carbon technological innovations in this promotion process. It is found that carbon finance significantly promotes clean energy development, but this contribution decreases with the intervention of low-carbon technology innovation. …”
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2646
Enhancing dimensional stability and weathering resistance of poplar wood through low-formaldehyde melamine resin impregnation and curing
Published 2025“…Density, anti-swelling efficiency, modulus of rupture, modulus of elasticity, compressive strength, and hardness all increased significantly in treated specimens. Impact resistance decreased slightly at higher concentrations, indicating increased brittleness. …”
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2647
Supplementary file 1_Bibliometrics-guided cyberpharmacology and transcriptomics for multidimensional analysis of the antihepatic fibrosis mechanism of kaempferol.docx
Published 2025“…Pharmacodynamic evaluations, including pathological section analyses, demonstrated that KA effectively mitigated the fibrotic process and decreased collagen deposition. Further corroborated by ELISA experiments, kaempferol exhibited pronounced anti-fibrotic effects, inhibited inflammatory responses, restored liver function indices, and ameliorated the progression of liver fibrosis. …”
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2648
Data Sheet 1_Iron modulates barrier integrity and stem cell function of small intestine during experimental colitis.docx
Published 2025“…</p>Results<p>It was shown that during DSS-induced colitis, small intestine underwent a serious injury process, including dysregulated integrity and decreased proliferation of ISCs. …”
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2649
Data Sheet 1_Pinostilbene inhibits lung epithelial-mesenchymal transition and delays pulmonary fibrosis by modulating the PI3K/Akt pathway.docx
Published 2025“…<p>Epithelial-mesenchymal transition (EMT) in the lung is a key process in which pulmonary epithelial cells lose epithelial characteristics and acquire mesenchymal properties, contributing to conditions such as pulmonary fibrosis. …”
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2650
Data Sheet 1_Variation and spread of resistomes in swine manure, manure slurries, and long-term manure-fertilized soils.docx
Published 2025“…High-risk ARG abundance significantly increased from 404.7 in manure to 843.2 in slurries, with health-risk scores rising 1.88-fold during anaerobic digestion. …”
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2651
Table1_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.docx
Published 2024“…Several hub genes, including ELMO1, YWHAE, and IL6ST, were significantly reduced in the placental vessels in preeclampsia. …”
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2652
Table2_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.xlsx
Published 2024“…Several hub genes, including ELMO1, YWHAE, and IL6ST, were significantly reduced in the placental vessels in preeclampsia. …”
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2653
Table4_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.xlsx
Published 2024“…Several hub genes, including ELMO1, YWHAE, and IL6ST, were significantly reduced in the placental vessels in preeclampsia. …”
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2654
Table3_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.xlsx
Published 2024“…Several hub genes, including ELMO1, YWHAE, and IL6ST, were significantly reduced in the placental vessels in preeclampsia. …”
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2655
Image 1_Construction of a novel cuproptosis-related gene signature for predicting microenvironment, prognosis and therapeutic response in cervical cancer.tif
Published 2025“…Moreover, the overexpression of FOXJ1 (one of the DEGs) significantly decreased the proliferation, invasion, migration and Epithelial-Mesenchymal Transition (EMT) process in cervical cancer cells. …”
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2656
Defective autophagy in vascular smooth muscle cells promote uremic accelerated atherosclerosis
Published 2025“…<p>Individuals with chronic kidney disease (CKD) exhibit a significantly elevated risk of premature mortality, predominantly attributable to cardiovascular etiologies. …”
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2657
Data Sheet 1_Development of a rapid fiber-detection system using artificial intelligence in phase-contrast microscope images of actual atmospheric samples.pdf
Published 2025“…Additionally, since the counting process relies on visual fiber counting, analytical accuracy can be decreased due to factors such as analyst fatigue. …”
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2658
Algorithm training accuracy experiments.
Published 2025“…In summary, the proposed change detection model significantly improves the accuracy and real-time performance of remote sensing image processing, contributing to the expanded application of remote sensing dynamic detection technology in fields such as ocean monitoring and ecological research.…”
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2659
Repeat the detection experiment.
Published 2025“…In summary, the proposed change detection model significantly improves the accuracy and real-time performance of remote sensing image processing, contributing to the expanded application of remote sensing dynamic detection technology in fields such as ocean monitoring and ecological research.…”
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2660
<b>Inhibition of NLRP3 Inflammasome Activation by Xylitol Attenuates </b><b><i>Fusobacterium nucleatum</i></b><b>-Driven Preterm Birth</b>
Published 2025“…Xylitol also exhibited antimicrobial effects against <i>F. nucleatum</i> within the uterine and placental tissues, correlating with decreased inflammasome activity. Notably, IL-1β levels in the placental labyrinth zone were significantly reduced in xylitol-treated, <i>F. nucleatum</i>-infected mice.…”