يعرض 18,421 - 18,440 نتائج من 21,342 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant progress decrease ))', وقت الاستعلام: 0.50s تنقيح النتائج
  1. 18421

    Table 3_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx حسب Linling Du (22827035)

    منشور في 2025
    "…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…"
  2. 18422

    ELOVL6 as a Therapeutic Target: Disrupting c-MYC-Driven Lipid Metabolism to Enhance Chemotherapy in Pancreatic Cancer حسب Ana García-García (17779885)

    منشور في 2025
    "…Initially, we show the direct regulation of ELOVLs expression by c-MYC in various PDAC mouse models and cell lines, elucidating its upregulation during transformation and tumor progression. Genetic or chemical inhibition of ELOVL6 results in decreased proliferation and migration, accompanied by alterations in fatty acid elongation. …"
  3. 18423

    Oral Astragalus polysaccharide alleviates adenine-induced kidney injury by regulating gut microbiota–short-chain fatty acids–kidney G protein-coupled receptors axis حسب Wenbo Liu (192914)

    منشور في 2024
    "…<p>Chronic kidney disease (CKD) can cause gut microbiota dysbiosis and decreasing production of short-chain fatty acids (SCFAs), which aggravate the injury of kidney. …"
  4. 18424

    Reactive Organic Gases from Vehicle Evaporative Emissions: Rates, Compositions, and Temperature Effects حسب Jun Lu (36049)

    منشور في 2025
    "…The emission composition shifted significantly across high-, normal-, and low-emitting vehicles: traditional hydrocarbons decreased progressively, while carbonyls/ketones increased, attenuating hydroxyl radical reactivity (OHR) reduction. …"
  5. 18425

    Table 13_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.docx حسب Linling Du (22827035)

    منشور في 2025
    "…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…"
  6. 18426

    Table1_Effect of inflammatory cytokines and plasma metabolome on OSA: a bidirectional two- sample Mendelian randomization study and mediation analysis.pdf حسب Xin Sun (127355)

    منشور في 2024
    "…These findings underscore the potential significance of inflammatory factors and metabolites in the genetic underpinnings of OSA development and prognosis.…"
  7. 18427

    Table 5_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis... حسب Minseo Kim (773205)

    منشور في 2025
    "…The hepatopancreas showed decreased expression of hemocyanin genes, which play key roles in oxygen transport and immune defense in crustaceans. …"
  8. 18428

    Data Sheet 1_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.pdf حسب Miguel Ângelo-Dias (20936444)

    منشور في 2025
    "…T cell activation progressively increased in CD4 and CD8 subsets, especially during late pregnancy. …"
  9. 18429

    Data Sheet 4_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.pdf حسب Miguel Ângelo-Dias (20936444)

    منشور في 2025
    "…T cell activation progressively increased in CD4 and CD8 subsets, especially during late pregnancy. …"
  10. 18430

    Table 11_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx حسب Linling Du (22827035)

    منشور في 2025
    "…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…"
  11. 18431

    Data Sheet 1_Epigallocatechin-3-gallate protects against osteoarthritis-induced chondrocytes dysfunction by regulating PLa2g2a.pdf حسب Mengyuan Dai (9747317)

    منشور في 2025
    "…OA model demonstrated that EGCG treatment significantly promoted cartilage repair and increased Pla2g2a expression. …"
  12. 18432

    DataSheet1_Identification of common signature genes and pathways underlying the pathogenesis association between nonalcoholic fatty liver disease and heart failure.docx حسب Gerui Li (15648920)

    منشور في 2024
    "…Experimental validation indicated unbalanced macrophage polarization in HF and NAFLD mouse models, and the expression of CD163 and CCR1 were significantly down-regulated.</p>Conclusion<p>This study identified M2 polarization impairment characterized by decreased expression of CD163 and CCR1 as a common pathogenic pathway in NAFLD and HF. …"
  13. 18433

    Table 1_Therapeutic potential of Triptolide in inhibiting breast cancer-induced bone destruction – PTHrP as a therapeutic target.docx حسب Wu Di (11561998)

    منشور في 2025
    "…Introduction<p>Bone metastases are a common and severe complication in advanced breast cancer, affecting approximately 65% to 70% of patients and significantly reducing survival time. Osteolytic bone metastases, in particular, are challenging to manage due to their association with skeletal-related events (SREs) that accelerate disease progression and diminish the quality of life. …"
  14. 18434

    Supplementary Material for: Impairment of Renal Function in Hermansky-Pudlak Syndrome حسب Yokoyama T. (4606381)

    منشور في 2024
    "…Linear regression analysis showed that renal function progressively decreases with age in patients with BLOC-3 or BLOC-2 disorders, but the rate of decline was more rapid in patients with BLOC-3 disorders compared to patients with BLOC-2 disorders. …"
  15. 18435

    PRMT5 isoforms during zebrafish developmental stages حسب Zain Zakaria (20354028)

    منشور في 2024
    "…NCBI database (version of 2019) was used in the searches. The significance of identification was set to p<0.5, one missed cleavage was allowed, and the expectation value was set to >0.95. …"
  16. 18436

    Image 2_Volumetric modulated arc therapy total body irradiation improves toxicity outcomes compared to 2D total body irradiation.jpeg حسب Caressa Hui (19676509)

    منشور في 2024
    "…However, there is limited evidence of whether improved organ sparing translates to decreases in toxicities and how its toxicities compare to those of the 2D technique. …"
  17. 18437

    Image 1_Volumetric modulated arc therapy total body irradiation improves toxicity outcomes compared to 2D total body irradiation.jpeg حسب Caressa Hui (19676509)

    منشور في 2024
    "…However, there is limited evidence of whether improved organ sparing translates to decreases in toxicities and how its toxicities compare to those of the 2D technique. …"
  18. 18438

    Table 2_IFN-treated macrophage-derived exosomes prevents HBV-HCC migration and invasion via regulating miR-106b-3p/PCGF3/PI3K/AKT signaling axis.docx حسب Jing Chen (4762)

    منشور في 2024
    "…Significantly increased expression of miR-106b-3p and decreased expression of HBsAg and HBV DNA were observed in Huh7-C2/B3 cells treated with IFN-exo. …"
  19. 18439

    Supplementary file 1_Bone marrow adipose tissue expansion and bone loss in experimental chronic kidney disease is independent of altered bone marrow stromal cell lineage determinat... حسب Worachet Promruk (22286701)

    منشور في 2025
    "…After 5-weeks’ induction, trabecular bone microarchitecture including bone mineral density was compromised whereas cortical bone area and thickness were decreased in CKD tibiae after 3- and 5-weeks’ induction. …"
  20. 18440

    Table 1_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.docx حسب Feifei Yang (334047)

    منشور في 2025
    "…Moreover, depletion of LAMs attenuated iron overload caused acceleration of AML progression.</p>Conclusions<p>Collectively, this study reveals the significance of iron overload in remodeling hematopoietic ecosystem and affecting HSC and LAM function in AML, providing new insights into the multifaceted role of iron overload in leukemia.…"