Prediction of the effect of the 9 nsSNPs on AKT2 proteins’ structure and function by eight computational tools. by Sadia Afrin Runa (22504971)

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Distribution of SNPs and their frequencies based on mutation classes. by Sadia Afrin Runa (22504971)

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Hydrogen bond interactions between Capivasertib (red) and the AKT2 protein (blue) as predicted by molecular docking analyses. by Sadia Afrin Runa (22504971)

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Hydrogen bond interactions between Ipatasertib (red) and the AKT2 protein (blue) as predicted by molecular docking analyses. by Sadia Afrin Runa (22504971)

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Hydrogen bond interactions between Akt1/Akt2-IN-1 (red) and the AKT2 protein (blue) as predicted by molecular docking analyses. by Sadia Afrin Runa (22504971)

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Predicted pathogenicity of R274H, Y265N, and R467W substitutions and their molecular mechanisms. by Sadia Afrin Runa (22504971)

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The Fig illustrates the effects of mutations on the stability, flexibility, compactness, and interactions of the AKT2-Akt1/Akt2-IN-1 through molecular dynamics simulations. by Sadia Afrin Runa (22504971)

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Non-covalent interactions between Capivasertib (ball stick) and the AKT2 protein as predicted by molecular docking analyses. by Sadia Afrin Runa (22504971)

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Non-covalent interactions between Akt1/Akt2-IN-1 (ball stick) and the AKT2 protein as predicted by molecular docking analyses. by Sadia Afrin Runa (22504971)

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Binding affinity of Akt1/Akt2-IN-1, Capivasertib, and Ipatasertib with AKT2 (wild and mutants) protein. by Sadia Afrin Runa (22504971)

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Superimposed structures of AKT2 native (green color) and mutant (red color) models to visualize the stereochemical conformation of wild type and mutant residues at (a) 274, (b) 265... by Sadia Afrin Runa (22504971)

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The Fig illustrates the effects of mutations on the stability, flexibility, compactness, and interactions of the AKT2-Ipatasertib complex through molecular dynamics simulations. by Sadia Afrin Runa (22504971)

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Non-covalent interactions between Ipatasertib (ball stick) and the AKT2 protein as predicted by molecular docking analyses. by Sadia Afrin Runa (22504971)

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The Fig appears to depict the results of conservation profile of amino acids of protein AKT2. by Sadia Afrin Runa (22504971)

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This Fig provides a comprehensive annotation of a AKT2 protein, depicting its domains, homologous superfamilies, active and binding sites, and other sites. by Sadia Afrin Runa (22504971)

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The Fig illustrates the effects of mutations on the stability, flexibility, compactness, and interactions of the AKT2- Capivasertib complex through molecular dynamics simulations. by Sadia Afrin Runa (22504971)

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Electroretinogram (ERG) recordings from 6-, 9-, and 12-month mice show deficits in 5xFAD photoreceptors. by Shaylah McCool (20818280)

NeuN staining of 6-, 9-, and 12-month dLGN sections shows loss of thalamocortical cell bodies in the 5xFAD mice. by Shaylah McCool (20818280)

Oscillatory potential (OP) analysis of 6-, 9-, and 12-month ERGs shows continued dysfunction in the inner retina reflecting A- and B-wave results. by Shaylah McCool (20818280)

Gene expression of the <i>hsp70Ab</i>-group and <i>hsp68</i> genes after baculovirus infection under different heat shock stimuli. by Enrique Paz-Cortés (20988196)

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