FAT1 and MIB2 control tumor growth <i>in vivo.</i> by Rui Li (4631)

FAT1 interacts with the E3 ligase MIB2. by Rui Li (4631)

Early and progressive microstructural damage is present in Fabry disease. by Jacob W. Johnson (20172850)

GSVA results. by Wan-Jing Zhen (20427813)

“…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…”

Differential expressed genes. by Wan-Jing Zhen (20427813)

“…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…”

S1 Raw image - by Wan-Jing Zhen (20427813)

“…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…”

Venn plot. by Wan-Jing Zhen (20427813)

“…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…”

Key module genes. by Wan-Jing Zhen (20427813)

“…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…”

Univariate and multivariate Cox analysis. by Wan-Jing Zhen (20427813)

“…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…”

S3 Fig - by Wan-Jing Zhen (20427813)

“…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…”

KEGG enrichment analysis. by Wan-Jing Zhen (20427813)

“…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…”

GSEA results. by Wan-Jing Zhen (20427813)

“…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…”

GO enrichment analysis. by Wan-Jing Zhen (20427813)

“…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…”

Flow chart of the study process. by Wan-Jing Zhen (20427813)

“…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…”

The degree score of 13 DE-ERSRGs. by Wan-Jing Zhen (20427813)

“…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…”

DE-ERSRGs-chemical interactive network. by Wan-Jing Zhen (20427813)

“…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…”

IRE1 depletion downregulates multiple cell cycle proteins in synchronized cells. by Iratxe Zuazo-Gaztelu (21071939)

Primary antibodies used for immunoblot analysis. by Iratxe Zuazo-Gaztelu (21071939)

“…IRE1 knockdown but not enzymatic IRE1 inhibition or XBP1 disruption attenuated cell cycle progression and tumor growth. IRE1 silencing led to activation of TP53 and CDKN1A/p21 in conjunction with increased DNA damage and chromosome instability, while decreasing heterochromatin as well as DNA and histone H3K9me3 methylation. …”

Fuchioka dataset 251021. by Yusuke Fuchioka (22806178)

“…</p><p>Conclusions</p><p>Quantitative 3D-MRI analysis revealed significant cartilage thickness decreases after OWHTO, predominantly in the medial aspect of the PF joint. …”

Data Sheet 1_Case report: Significant lesion reduction and neural structural changes following ibogaine treatments for multiple sclerosis.docx by David Qixiang Chen (8198265)

“…Traditional therapies often fail to halt disease progression or reverse neurological deficits. Ibogaine, a psychoactive alkaloid, has been proposed as a potential neuroregenerative agent due to its multifaceted pharmacological profile. …”