Table 3_Analysis of global trends in acute lymphoblastic leukemia in children aged 0–5 years from 1990 to 2021.docx by Fang Ding (222713)

“…Background<p>Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with a significant global burden. This study evaluates global, regional, and national trends in the prevalence, mortality, and disability-adjusted life years (DALYs) of childhood ALL from 1990 to 2021, providing insights into disparities and progress across different socio-demographic and geographic contexts.…”

Supplementary tables: Assessing healthcare resource utilization burden and unmet treatment needs in patients with Parkinson’s disease: results from a real-world study by Malgorzata Ciepielewska (22143499)

“…The intermediate versus early group had a significantly greater proportion of patients with unmet treatment needs (p < 0.001), e.g., slowing disease progression, providing neuroprotection. …”

Data Sheet 1_Cynaroside ameliorates TNBS-induced colitis by inhibiting intestinal epithelial cell apoptosis via the PI3K/AKT signalling pathway.pdf by figshare admin frontiersin (4545187)

“…Combining network pharmacology prediction analysis with our validation data from animal models and colonic organoids, we demonstrated that Cyn significantly inhibits IEC apoptosis, as indicated by a decrease in the proportion of TUNEL-positive cells and changes in apoptosis-related protein levels. …”

Supplementary data: Assessing healthcare resource utilization burden and unmet treatment needs in patients with Parkinson’s disease: results from a real-world study by Malgorzata Ciepielewska (22143499)

“…The intermediate versus early group had a significantly greater proportion of patients with unmet treatment needs (p < 0.001), e.g., slowing disease progression, providing neuroprotection. …”

Data Sheet 4_Balanophora polysaccharide improves renal injury and fibrosis in db/db diabetic nephropathy mice via NLRP3 inflammasome mediated inflammation.pdf by Chaoxi Tian (22702289)

“…Additionally, it improved renal function and effectively alleviated renal injury. Moreover, BPS decreased the expression of extracellular matrix (ECM) proteins and inhibited ECM deposition, thereby alleviating the progression of renal fibrosis in DN and reducing cell apoptosis. …”

Data Sheet 2_Balanophora polysaccharide improves renal injury and fibrosis in db/db diabetic nephropathy mice via NLRP3 inflammasome mediated inflammation.pdf by Chaoxi Tian (22702289)

“…Additionally, it improved renal function and effectively alleviated renal injury. Moreover, BPS decreased the expression of extracellular matrix (ECM) proteins and inhibited ECM deposition, thereby alleviating the progression of renal fibrosis in DN and reducing cell apoptosis. …”

Data Sheet 1_Balanophora polysaccharide improves renal injury and fibrosis in db/db diabetic nephropathy mice via NLRP3 inflammasome mediated inflammation.pdf by Chaoxi Tian (22702289)

“…Additionally, it improved renal function and effectively alleviated renal injury. Moreover, BPS decreased the expression of extracellular matrix (ECM) proteins and inhibited ECM deposition, thereby alleviating the progression of renal fibrosis in DN and reducing cell apoptosis. …”

Data Sheet 3_Balanophora polysaccharide improves renal injury and fibrosis in db/db diabetic nephropathy mice via NLRP3 inflammasome mediated inflammation.pdf by Chaoxi Tian (22702289)

“…Additionally, it improved renal function and effectively alleviated renal injury. Moreover, BPS decreased the expression of extracellular matrix (ECM) proteins and inhibited ECM deposition, thereby alleviating the progression of renal fibrosis in DN and reducing cell apoptosis. …”

Computational insights into <i>PKCθ</i> non-synonymous SNPs: from structural changes to functional implications by Amna Hafeez (14016805)

“…Conservation profiling highlighted the evolutionary significance of these residues, indicating their critical roles in protein function. …”

Data Sheet 1_Neuronal expression of S100B triggered by oligomeric Aβ peptide contributes to protection against cytoskeletal damage and synaptic loss.docx by Joana Saavedra (11327910)

“…In this work, we investigated if S100B neuronal expression is triggered as a response to Aβ toxic species, to provide protection during disease progression. We used the AD mouse model AβPPswe/PS1A246E to show that neuronal S100B levels are significantly higher in 10-month-old animals, and cellular assays to demonstrate that Aβ oligomers significantly increase S100B expression in SH-SY5Y cells, but not monomeric or fibrillar Aβ. …”

Image 3_Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barri... by Ning Ding (456674)

“…Background<p>Gut microbiota dysbiosis is closely related to the occurrence and progression of Alzheimer’s disease (AD). The destruction of the intestinal mucosal barrier caused by a decrease in short-chain fatty acids (SCFAs) plays a key role in gut microbiota dysbiosis-induced neuroinflammation in AD. …”

<b>Cannabinoid Receptor 2 Agonism Demonstrates Therapeutic </b><b>Potential in Experimental Models of Relevance to Diabetic Retinopathy</b> by Cayla D. Ontko (21434062)

“…<i>In vivo</i>, both intraocular and systemic HU-308 administration significantly decreased retinal leukostasis in cytokine-induced inflammation and STZ-induced diabetes. …”

Image 1_Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barri... by Ning Ding (456674)

“…Background<p>Gut microbiota dysbiosis is closely related to the occurrence and progression of Alzheimer’s disease (AD). The destruction of the intestinal mucosal barrier caused by a decrease in short-chain fatty acids (SCFAs) plays a key role in gut microbiota dysbiosis-induced neuroinflammation in AD. …”

Image 4_Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barri... by Ning Ding (456674)

“…Background<p>Gut microbiota dysbiosis is closely related to the occurrence and progression of Alzheimer’s disease (AD). The destruction of the intestinal mucosal barrier caused by a decrease in short-chain fatty acids (SCFAs) plays a key role in gut microbiota dysbiosis-induced neuroinflammation in AD. …”

Table 1_Efficacy and safety of cadonilimab combined with AG chemotherapy in patients with unresectable locally advanced or metastatic pancreatic ductal adenocarcinoma: a retrospect... by Wenke Qin (20390989)

“…Among patients with a decrease in CA19-9, the median overall survival was significantly prolonged (12.92 vs 8.89 months, P = 0.027); patients with a platelet-lymphocyte ratio (PLR) ≤ 165.62 had a significantly better mOS (12.37 vs 8.74 months, P = 0.025). …”

Table 1_Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barri... by Ning Ding (456674)

“…Background<p>Gut microbiota dysbiosis is closely related to the occurrence and progression of Alzheimer’s disease (AD). The destruction of the intestinal mucosal barrier caused by a decrease in short-chain fatty acids (SCFAs) plays a key role in gut microbiota dysbiosis-induced neuroinflammation in AD. …”

Image 2_Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barri... by Ning Ding (456674)

“…Background<p>Gut microbiota dysbiosis is closely related to the occurrence and progression of Alzheimer’s disease (AD). The destruction of the intestinal mucosal barrier caused by a decrease in short-chain fatty acids (SCFAs) plays a key role in gut microbiota dysbiosis-induced neuroinflammation in AD. …”

Table 6_Quantitative proteomic analysis reveals potential serum diagnostic markers for colorectal adenoma.xlsx by Chengli Yu (1445185)

“…In contrast, FLNA levels measured by ELISA showed a progressive decrease from healthy controls to patients with inflammatory polyps and further to those with adenomas. …”

Table 2_Quantitative proteomic analysis reveals potential serum diagnostic markers for colorectal adenoma.xlsx by Chengli Yu (1445185)

“…In contrast, FLNA levels measured by ELISA showed a progressive decrease from healthy controls to patients with inflammatory polyps and further to those with adenomas. …”

Table 3_Quantitative proteomic analysis reveals potential serum diagnostic markers for colorectal adenoma.xlsx by Chengli Yu (1445185)

“…In contrast, FLNA levels measured by ELISA showed a progressive decrease from healthy controls to patients with inflammatory polyps and further to those with adenomas. …”