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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
progress decrease » progressive decrease (Expand Search), problems decreased (Expand Search)
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1581
DataSheet2_Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease.xlsx
Published 2024“…</p>Results<p>Metabolic characteristics revealed significant shifts in CKD, with 61 metabolites increased and 65 metabolites decreased, highlighting the disruption in steroid hormone biosynthesis pathways influenced by HSD3B2. …”
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1582
DataSheet1_Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease.pdf
Published 2024“…</p>Results<p>Metabolic characteristics revealed significant shifts in CKD, with 61 metabolites increased and 65 metabolites decreased, highlighting the disruption in steroid hormone biosynthesis pathways influenced by HSD3B2. …”
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1583
Table 1_Berberine alleviates atherosclerosis by modulating autophagy and inflammation through the RAGE-NF-κB pathway.docx
Published 2025“…Introduction<p>Lipid accumulation and foam cell formation are significant features that expedite the progression of atherosclerosis (AS). …”
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1584
Supplementary file 1_Succession characteristics and assembly process of soil microbiome at reclaimed farmlands in coal mining area.doc
Published 2025“…Results showed that (1) Compared to R0, the R10 treatment resulted in significant increases in soil organic matter (SOM), total nitrogen (TN), available phosphorus (AP), and available potassium (AK) by 2.1-fold, 1.3-fold, 1.5-fold, and 0.4-fold, and also in activities of β-glucosidase (BG), N-acetyl-β-glucosaminidase (NAG), and leucine aminopeptidase (LAP), by 17-fold, 8.7-fold, and 1.8-fold, respectively (p < 0.05). (2) Rising bacterial diversity (Shannon, Chao1) over time, contrasting with fungal diversity that declined initially before recovering. (3) As the reclamation progressed, the network complexity was increased for both bacteria and fungi, improving stability. …”
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1585
Identification of novel pathogenic mutations in <i>ATP6V0A4</i> associated with distal renal tubular acidosis and analysis of wild-type expression in glomerular disease
Published 2025“…If untreated, it can result in a significant electrolyte imbalance and progressive chronic kidney disease (CKD). …”
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1586
Table 6_MicroRNAs regulate alveolar macrophage homeostasis and its function in lung fibrosis.xlsx
Published 2025“…Introduction<p>Idiopathic pulmonary fibrosis is a progressive lung disease with a poor prognosis. Alveolar macrophages (AMs) are essential for maintaining lung homeostasis and play a significant role in the development of lung fibrosis. …”
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1587
Supplementary Material for: Exosomal TIMP4 from myocardial cell relieves heart failure by influencing Th17/Treg Balance
Published 2025“…Introduction: The progression of heart failure (HF) has been independently linked to both tissue inhibitor of metalloproteinase-4 (TIMP4) and the equilibrium between regulatory T (Treg) as well as T helper 17 (Th17) cells. …”
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1588
Effects of task optimization on pareidolia representations in CNNs.
Published 2025“…Conversely, in CNNs lacking object categorization training (Panels B, C), this similarity was weak, only reaching significance at early layers, and decreased across layers. …”
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1589
Supplementary file 1_Dynamic mechanical stimulation of alveolar epithelial-fibroblast models using the Flexcell tension system to study of lung disease mechanisms.docx
Published 2025“…<p>Mechanical strain plays a significant role in lung pathophysiology. Current two-dimensional (2D) in vitro models fail to capture the lung's dynamic mechanical environment. …”
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1590
Table 2_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.docx
Published 2024“…The frequency and duration of vertigo attacks generally decreased over time, with attacks becoming shorter and less severe as the disease progressed. …”
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1591
Data Sheet 3_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.pdf
Published 2024“…The frequency and duration of vertigo attacks generally decreased over time, with attacks becoming shorter and less severe as the disease progressed. …”
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1592
Table 3_MicroRNAs regulate alveolar macrophage homeostasis and its function in lung fibrosis.xlsx
Published 2025“…Introduction<p>Idiopathic pulmonary fibrosis is a progressive lung disease with a poor prognosis. Alveolar macrophages (AMs) are essential for maintaining lung homeostasis and play a significant role in the development of lung fibrosis. …”
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1593
Image 1_Multi level effects of Sanghuang Tongxie Formula on type 2 diabetes rats: a comprehensive analysis from intestinal bacteria to metabolome and transcriptome.tif
Published 2025“…</p>Results<p>SHTX treatment significantly altered the gut microbiota composition in T2DM rats, increasing the relative abundance of Bacteroidetes while decreasing that of Firmicutes, which was closely correlated with improved insulin sensitivity. …”
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1594
Table 1_The role of gut microbiota in modulating immune responses in chronic liver disease: a systematic review and meta-analysis.docx
Published 2025“…Interleukin-6 (IL-6) levels showed no significant change between the groups (SMD, -0.67; 95% CI [-1.5, 0.12) p = 0.09). …”
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1595
Table 1_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.docx
Published 2024“…The frequency and duration of vertigo attacks generally decreased over time, with attacks becoming shorter and less severe as the disease progressed. …”
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1596
Data Sheet 2_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.pdf
Published 2024“…The frequency and duration of vertigo attacks generally decreased over time, with attacks becoming shorter and less severe as the disease progressed. …”
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1597
Table 4_MicroRNAs regulate alveolar macrophage homeostasis and its function in lung fibrosis.xlsx
Published 2025“…Introduction<p>Idiopathic pulmonary fibrosis is a progressive lung disease with a poor prognosis. Alveolar macrophages (AMs) are essential for maintaining lung homeostasis and play a significant role in the development of lung fibrosis. …”
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1598
Table 1_Lumefantrine ameliorates DSS-induced colitis by targeting FLI-1 to suppress NF-κB signaling.docx
Published 2025“…Mice received oral Lumefantrine (20 mg/kg/day) for 7 days. Disease progression was monitored via disease activity index (DAI) scoring and histological analysis. …”
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1599
Data Sheet 1_Multi level effects of Sanghuang Tongxie Formula on type 2 diabetes rats: a comprehensive analysis from intestinal bacteria to metabolome and transcriptome.xlsx
Published 2025“…</p>Results<p>SHTX treatment significantly altered the gut microbiota composition in T2DM rats, increasing the relative abundance of Bacteroidetes while decreasing that of Firmicutes, which was closely correlated with improved insulin sensitivity. …”
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1600
Table 5_MicroRNAs regulate alveolar macrophage homeostasis and its function in lung fibrosis.xlsx
Published 2025“…Introduction<p>Idiopathic pulmonary fibrosis is a progressive lung disease with a poor prognosis. Alveolar macrophages (AMs) are essential for maintaining lung homeostasis and play a significant role in the development of lung fibrosis. …”