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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
progress decrease » progressive decrease (Expand Search), problems decreased (Expand Search)
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1601
Data Sheet 1_Multi-compartment immune cell profiling highlights the prognostic relevance of CD127+ CD8+ T cells for patients with high-grade serous ovarian cancer.docx
Published 2025“…In addition, immune cell subsets varied significantly in their differentiation and phenotypic marker expression. …”
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1602
Image 2_Interleukin-26 expression in tuberculosis disease and its regulatory effect in macrophage polarization and intracellular elimination of Mycobacterium tuberculosis.jpeg
Published 2024“…<p>Tuberculosis(TB), an infectious disease caused by Mycobacterium tuberculosis (Mtb) infections, remains the leading cause of mortality from a single infectious agent globally. The progression of tuberculosis disease is contingent upon the complex interplay between the host’s immune system and the pathogen Mtb. …”
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1603
Data Sheet 1_Visual attention during non-immersive virtual reality balance training in older adults with mild to moderate cognitive impairment: an eye-tracking study.pdf
Published 2025“…</p>Results<p>Patients showed a small numerical increase, without reaching statistical significance in task difficulty progression (p = 0.016), lower limb endurance (p = 0.016), and single-leg support time (p = 0.031). …”
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1604
Video 2_Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS.mp4
Published 2025“…Notably, the effects of Bet1L knockdown on NMJ and motor neuron degeneration were more significant in ALS rats when compared to WT rats. Together, Bet1L knockdown induces denervation of NMJs, but also this knockdown accelerates the disease progression in ALS. …”
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1605
Table 2_High intake of n-6 polyunsaturated fatty acid exacerbates non-alcoholic steatohepatitis by the involvement of multiple metabolic pathways.docx
Published 2025“…Correlational analysis revealed significant associations between these pathways and inflammatory/oxidative markers. …”
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1606
Table 1_Cholesterol metabolic reprogramming drives the onset of DLBCL and represents a promising therapeutic target.docx
Published 2025“…</p>Results<p>We confirmed significant alterations in metabolic markers (such as TC and ApoA1) between the healthy control group and patients, which were significantly associated with patient prognosis and overall OS. …”
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1607
Video 1_Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS.mp4
Published 2025“…Notably, the effects of Bet1L knockdown on NMJ and motor neuron degeneration were more significant in ALS rats when compared to WT rats. Together, Bet1L knockdown induces denervation of NMJs, but also this knockdown accelerates the disease progression in ALS. …”
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1608
Table 2_MicroRNAs regulate alveolar macrophage homeostasis and its function in lung fibrosis.xlsx
Published 2025“…Introduction<p>Idiopathic pulmonary fibrosis is a progressive lung disease with a poor prognosis. Alveolar macrophages (AMs) are essential for maintaining lung homeostasis and play a significant role in the development of lung fibrosis. …”
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1609
Table 1_Proton therapy achieves high-dose tumor control with organ preservation in complex metastatic adenoid cystic carcinoma: a case report of a refractory patient with 16 pulmon...
Published 2025“…It aims to delay disease progression and achieve organ preservation in refractory ACC.…”
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1610
Supplementary file 1_Clinical characteristics and mortality risk factors among hospitalized infants and children with pertussis in China: a retrospective study.docx
Published 2025“…Common clinical features of severe pertussis include pneumonia, respiratory failure, elevated WBC count, and decreased neutrophil percentage. Pediatricians should prioritize early recognition and treatment of these clinical indicators to prevent the progression of severe pertussis.…”
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1611
Table 1_MicroRNAs regulate alveolar macrophage homeostasis and its function in lung fibrosis.xlsx
Published 2025“…Introduction<p>Idiopathic pulmonary fibrosis is a progressive lung disease with a poor prognosis. Alveolar macrophages (AMs) are essential for maintaining lung homeostasis and play a significant role in the development of lung fibrosis. …”
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1612
Data Sheet 1_The relationship between inflammatory factors and heart failure: evidence based on bidirectional Mendelian randomization analysis.zip
Published 2024“…Objective<p>Inflammatory factors play a crucial role in the onset and progression of heart failure. To further explore the causal relationship between inflammatory factors and heart failure, we employed bidirectional Mendelian randomization analysis to investigate the causal links between 91 inflammatory cytokines and heart failure.…”
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1613
Image 4_Interleukin-26 expression in tuberculosis disease and its regulatory effect in macrophage polarization and intracellular elimination of Mycobacterium tuberculosis.jpeg
Published 2024“…<p>Tuberculosis(TB), an infectious disease caused by Mycobacterium tuberculosis (Mtb) infections, remains the leading cause of mortality from a single infectious agent globally. The progression of tuberculosis disease is contingent upon the complex interplay between the host’s immune system and the pathogen Mtb. …”
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1614
Data Sheet 1_Interleukin-26 expression in tuberculosis disease and its regulatory effect in macrophage polarization and intracellular elimination of Mycobacterium tuberculosis.xlsx
Published 2024“…<p>Tuberculosis(TB), an infectious disease caused by Mycobacterium tuberculosis (Mtb) infections, remains the leading cause of mortality from a single infectious agent globally. The progression of tuberculosis disease is contingent upon the complex interplay between the host’s immune system and the pathogen Mtb. …”
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1615
Image 1_Safety profile and efficacy of secukinumab in the treatment of autoimmune myasthenia gravis: a single-center retrospective study.jpeg
Published 2025“…Th17 cell frequency and IL-17 levels decreased by 68 and 84.47%, respectively. Strong baseline correlations were observed between IL-17, Th17, and clinical scores (r = 0.642–0.970, p < 0.001), with progressive uncoupling of these relationships during treatment. …”
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1616
Table 1_Blood urea nitrogen-to-albumin ratio as a new prognostic indicator of 1-year all-cause mortality in patients with IPF.docx
Published 2025“…The Kaplan–Meier survival curve showed that the 1-year cumulative survival rate of IPF patients with a BAR ≥0.12 was significantly decreased compared with the patients with a BAR <0.12. …”
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1617
Image 6_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.tif
Published 2024“…The frequency and duration of vertigo attacks generally decreased over time, with attacks becoming shorter and less severe as the disease progressed. …”
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1618
CircFNDC3B inhibits vascular smooth muscle cells proliferation in abdominal aortic aneurysms by targeting the miR-1270/PDCD10 axis
Published 2024“…</i> This study demonstrates that circFNDC3B promotes the progression of AAA by targeting the miR-1270/PDCD10 pathway. …”
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1619
Data Sheet 1_Isobavachalcone ameliorates Alzheimer disease pathology by autophagy-mediated clearance of amyloid beta and inhibition of NLRP3 inflammasome in primary astrocytes and...
Published 2025“…Background and Aim<p>Alzheimer’s disease (AD) progresses with Aβ plaque deposition and neuroinflammation. …”
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1620
Data Sheet 1_Safety profile and efficacy of secukinumab in the treatment of autoimmune myasthenia gravis: a single-center retrospective study.pdf
Published 2025“…Th17 cell frequency and IL-17 levels decreased by 68 and 84.47%, respectively. Strong baseline correlations were observed between IL-17, Th17, and clinical scores (r = 0.642–0.970, p < 0.001), with progressive uncoupling of these relationships during treatment. …”