بدائل البحث:
significant progressive » significant progress (توسيع البحث), significant protective (توسيع البحث), significant processes (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
progressive decrease » progressive decline (توسيع البحث)
significant progressive » significant progress (توسيع البحث), significant protective (توسيع البحث), significant processes (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
progressive decrease » progressive decline (توسيع البحث)
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1981
Table 7_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis...
منشور في 2025"…The hepatopancreas showed decreased expression of hemocyanin genes, which play key roles in oxygen transport and immune defense in crustaceans. …"
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1982
Table 3_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx
منشور في 2025"…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…"
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1983
ELOVL6 as a Therapeutic Target: Disrupting c-MYC-Driven Lipid Metabolism to Enhance Chemotherapy in Pancreatic Cancer
منشور في 2025"…Initially, we show the direct regulation of ELOVLs expression by c-MYC in various PDAC mouse models and cell lines, elucidating its upregulation during transformation and tumor progression. Genetic or chemical inhibition of ELOVL6 results in decreased proliferation and migration, accompanied by alterations in fatty acid elongation. …"
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1984
Oral Astragalus polysaccharide alleviates adenine-induced kidney injury by regulating gut microbiota–short-chain fatty acids–kidney G protein-coupled receptors axis
منشور في 2024"…<p>Chronic kidney disease (CKD) can cause gut microbiota dysbiosis and decreasing production of short-chain fatty acids (SCFAs), which aggravate the injury of kidney. …"
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1985
Reactive Organic Gases from Vehicle Evaporative Emissions: Rates, Compositions, and Temperature Effects
منشور في 2025"…The emission composition shifted significantly across high-, normal-, and low-emitting vehicles: traditional hydrocarbons decreased progressively, while carbonyls/ketones increased, attenuating hydroxyl radical reactivity (OHR) reduction. …"
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1986
Table 13_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.docx
منشور في 2025"…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…"
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1987
Table1_Effect of inflammatory cytokines and plasma metabolome on OSA: a bidirectional two- sample Mendelian randomization study and mediation analysis.pdf
منشور في 2024"…Inflammatory factors and plasma metabolites are important in assessing its progression. However, the causal relationship between them and OSA remains unclear, hampering early clinical diagnosis and treatment decisions.…"
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1988
Table 5_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis...
منشور في 2025"…The hepatopancreas showed decreased expression of hemocyanin genes, which play key roles in oxygen transport and immune defense in crustaceans. …"
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1989
Data Sheet 1_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.pdf
منشور في 2025"…T cell activation progressively increased in CD4 and CD8 subsets, especially during late pregnancy. …"
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1990
Data Sheet 4_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.pdf
منشور في 2025"…T cell activation progressively increased in CD4 and CD8 subsets, especially during late pregnancy. …"
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1991
Table 11_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx
منشور في 2025"…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…"
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1992
Data Sheet 1_Epigallocatechin-3-gallate protects against osteoarthritis-induced chondrocytes dysfunction by regulating PLa2g2a.pdf
منشور في 2025"…OA model demonstrated that EGCG treatment significantly promoted cartilage repair and increased Pla2g2a expression. …"
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1993
DataSheet1_Identification of common signature genes and pathways underlying the pathogenesis association between nonalcoholic fatty liver disease and heart failure.docx
منشور في 2024"…Experimental validation indicated unbalanced macrophage polarization in HF and NAFLD mouse models, and the expression of CD163 and CCR1 were significantly down-regulated.</p>Conclusion<p>This study identified M2 polarization impairment characterized by decreased expression of CD163 and CCR1 as a common pathogenic pathway in NAFLD and HF. …"
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1994
Table 1_Therapeutic potential of Triptolide in inhibiting breast cancer-induced bone destruction – PTHrP as a therapeutic target.docx
منشور في 2025"…Introduction<p>Bone metastases are a common and severe complication in advanced breast cancer, affecting approximately 65% to 70% of patients and significantly reducing survival time. Osteolytic bone metastases, in particular, are challenging to manage due to their association with skeletal-related events (SREs) that accelerate disease progression and diminish the quality of life. …"
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1995
Supplementary Material for: Impairment of Renal Function in Hermansky-Pudlak Syndrome
منشور في 2024"…Linear regression analysis showed that renal function progressively decreases with age in patients with BLOC-3 or BLOC-2 disorders, but the rate of decline was more rapid in patients with BLOC-3 disorders compared to patients with BLOC-2 disorders. …"
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1996
Image 2_Volumetric modulated arc therapy total body irradiation improves toxicity outcomes compared to 2D total body irradiation.jpeg
منشور في 2024"…However, there is limited evidence of whether improved organ sparing translates to decreases in toxicities and how its toxicities compare to those of the 2D technique. …"
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1997
Image 1_Volumetric modulated arc therapy total body irradiation improves toxicity outcomes compared to 2D total body irradiation.jpeg
منشور في 2024"…However, there is limited evidence of whether improved organ sparing translates to decreases in toxicities and how its toxicities compare to those of the 2D technique. …"
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1998
Table 2_IFN-treated macrophage-derived exosomes prevents HBV-HCC migration and invasion via regulating miR-106b-3p/PCGF3/PI3K/AKT signaling axis.docx
منشور في 2024"…Significantly increased expression of miR-106b-3p and decreased expression of HBsAg and HBV DNA were observed in Huh7-C2/B3 cells treated with IFN-exo. …"
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1999
Supplementary file 1_Bone marrow adipose tissue expansion and bone loss in experimental chronic kidney disease is independent of altered bone marrow stromal cell lineage determinat...
منشور في 2025"…After 5-weeks’ induction, trabecular bone microarchitecture including bone mineral density was compromised whereas cortical bone area and thickness were decreased in CKD tibiae after 3- and 5-weeks’ induction. …"
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2000
Table 1_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.docx
منشور في 2025"…Moreover, depletion of LAMs attenuated iron overload caused acceleration of AML progression.</p>Conclusions<p>Collectively, this study reveals the significance of iron overload in remodeling hematopoietic ecosystem and affecting HSC and LAM function in AML, providing new insights into the multifaceted role of iron overload in leukemia.…"