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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
progressive decrease » progressive decline (Expand Search)
significant progressive » significant progress (Expand Search), significant protective (Expand Search), significant processes (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
progressive decrease » progressive decline (Expand Search)
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1341
Data Sheet 1_Changes of brain structure and structural covariance networks in Parkinson’s disease with different sides of onset.docx
Published 2025“…Background<p>Parkinson’s disease (PD) typically presents with unilateral symptoms in early stages, starting on one side and progressing, with the onset side showing more severe motor symptoms even after bilateralization. …”
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1342
Hypoxia-inducible factor-1α promotes tubulointerstitial fibrosis via the upregulation of <i>Muc4</i>
Published 2025“…Then, the results of transcriptomic analysis and <i>in vivo</i> and <i>in vitro</i> experiments revealed that expression of Mucin 4 (MUC4) was significantly decreased at the transcriptional and protein levels in tubular HIF-1α-knockout mice. …”
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1343
Identification of Alzheimer’s disease susceptibility genes by the integration of genomics and transcriptomics
Published 2025“…Through Mendelian randomization (MR) analysis, it was found that the risk of AD was significantly increased when VASP expression increased (OR = 0.1.046), while the risk of AD was significantly decreased when SURF2 (OR = 0.897) and TARBP1(OR = 0.920) expression increased. …”
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1344
Regional differences in cholinergic sweating in the lower limb
Published 2025“…<p dir="ltr">It remains unclear how progressive aging alters regional differences in cholinergic sweat gland function across lower limb sites. …”
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1345
Pioneering study - Impact of positive thinking on patients with chronic pain
Published 2024“…</p><p dir="ltr">Conversely, the intervention group showed significant positive outcomes. Of the 113 patients, 105 reported a decreased perception of pain, suggesting a substantial impact of the positive thinking exercises. …”
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1346
Table 1_Inflammatory parameters mediates the relationship between dietary index for gut microbiota and frailty in middle-aged and older adults in the United States: findings from a...
Published 2025“…RCS showed that the risk of frailty decreased linearly with increasing DI-GM levels. Mediation analysis indicated significant effects for leukocyte count, neutrophil count, NLR, and SIRI, with mediation proportions of 5.7, 7.9, 4.4, and 5.5%, respectively (all p < 0.001).…”
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1347
Table 4_Analysis of global trends in acute lymphoblastic leukemia in children aged 0–5 years from 1990 to 2021.docx
Published 2025“…Background<p>Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with a significant global burden. This study evaluates global, regional, and national trends in the prevalence, mortality, and disability-adjusted life years (DALYs) of childhood ALL from 1990 to 2021, providing insights into disparities and progress across different socio-demographic and geographic contexts.…”
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1348
Image 1_Analysis of global trends in acute lymphoblastic leukemia in children aged 0–5 years from 1990 to 2021.tif
Published 2025“…Background<p>Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with a significant global burden. This study evaluates global, regional, and national trends in the prevalence, mortality, and disability-adjusted life years (DALYs) of childhood ALL from 1990 to 2021, providing insights into disparities and progress across different socio-demographic and geographic contexts.…”
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1349
Table 2_Analysis of global trends in acute lymphoblastic leukemia in children aged 0–5 years from 1990 to 2021.docx
Published 2025“…Background<p>Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with a significant global burden. This study evaluates global, regional, and national trends in the prevalence, mortality, and disability-adjusted life years (DALYs) of childhood ALL from 1990 to 2021, providing insights into disparities and progress across different socio-demographic and geographic contexts.…”
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1350
Table 1_Analysis of global trends in acute lymphoblastic leukemia in children aged 0–5 years from 1990 to 2021.docx
Published 2025“…Background<p>Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with a significant global burden. This study evaluates global, regional, and national trends in the prevalence, mortality, and disability-adjusted life years (DALYs) of childhood ALL from 1990 to 2021, providing insights into disparities and progress across different socio-demographic and geographic contexts.…”
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1351
Table 3_Analysis of global trends in acute lymphoblastic leukemia in children aged 0–5 years from 1990 to 2021.docx
Published 2025“…Background<p>Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with a significant global burden. This study evaluates global, regional, and national trends in the prevalence, mortality, and disability-adjusted life years (DALYs) of childhood ALL from 1990 to 2021, providing insights into disparities and progress across different socio-demographic and geographic contexts.…”
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1352
Supplementary file 1_Rotation of soybean and Corydalis yanhusuo enhances yield and active compounds of C. yanhusuo via soil nutrient optimisation and rhizosphere microbiome enginee...
Published 2025“…Microbial OTUs increased in the bulk soil, rhizosphere soil, and roots, along with significant improvements in α-diversity. Over time, the Proteobacteria and pathogenic genera decreased, while Firmicutes and other beneficial genera increased. …”
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1353
Data Sheet 1_Systemic lipid and glucose modulation differentially affects cognitive function and neuroinflammation in a mouse model of Alzheimer’s disease.xlsx
Published 2025“…Introduction<p>Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by synaptic dysfunction and cognitive decline. …”
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1354
Data Sheet 1_Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia.pdf
Published 2025“…In the sarcopenia group, both GPRC5D-AS1 and SLC7A11 expression levels decreased significantly, along with SLC7A11 protein translation. …”
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1355
Supplementary file 1_Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia.pdf
Published 2025“…In the sarcopenia group, both GPRC5D-AS1 and SLC7A11 expression levels decreased significantly, along with SLC7A11 protein translation. …”
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1356
Supplementary file 1_Systemic lipid and glucose modulation differentially affects cognitive function and neuroinflammation in a mouse model of Alzheimer’s disease.docx
Published 2025“…Introduction<p>Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by synaptic dysfunction and cognitive decline. …”
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1357
Table 1_Spontaneous neural activity alterations in medication-naïve primary blepharospasm: a resting-state functional magnetic resonance imaging study.docx
Published 2025“…</p>Results<p>Compared to healthy controls, medication-naïve patients with BSP exhibited significantly increased ALFF in the bilateral putamen and left premotor cortex and decreased ALFF in the bilateral thalamus (p < 0.05, threshold-free cluster enhancement with family-wise error correction for multiple comparisons). …”
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1358
Table_1_Refugees’ integration and emotional distress over the course of 9 months.pdf
Published 2024“…</p>Results<p>Overall, emotional distress decreased, and integration increased over time. In particular, the sub-dimensions of social, economic, and linguistic integration increased significantly over time<sub>.…”
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1359
Table_1_Refugees’ integration and emotional distress over the course of 9 months.pdf
Published 2024“…</p>Results<p>Overall, emotional distress decreased, and integration increased over time. In particular, the sub-dimensions of social, economic, and linguistic integration increased significantly over time<sub>.…”
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1360
Table 1_A case report: enhanced somatostatin receptor expression in metastatic pancreatic neuroendocrine tumor following everolimus therapy.pdf
Published 2025“…However, in August 2022, MRI scans indicated disease progression, leading to discontinuation of octreotide. …”