Image 2_A case report: enhanced somatostatin receptor expression in metastatic pancreatic neuroendocrine tumor following everolimus therapy.pdf by Pei Zhang (232846)

“…However, in August 2022, MRI scans indicated disease progression, leading to discontinuation of octreotide. …”

Table 2_A case report: enhanced somatostatin receptor expression in metastatic pancreatic neuroendocrine tumor following everolimus therapy.pdf by Pei Zhang (232846)

“…However, in August 2022, MRI scans indicated disease progression, leading to discontinuation of octreotide. …”

Data Sheet 1_Promoting the development and approval of new traditional Chinese medicines in China: a pooled analysis of data from 2013 to 2024.docx by Xiaohong Long (20871797)

“…Although the review time for TCMs has significantly decreased after the reform, the overall development time has increased. …”

Image 1_A case report: enhanced somatostatin receptor expression in metastatic pancreatic neuroendocrine tumor following everolimus therapy.pdf by Pei Zhang (232846)

“…However, in August 2022, MRI scans indicated disease progression, leading to discontinuation of octreotide. …”

Molecular features influencing clinical outcome of advanced HER2-positive gastric cancer receiving trastuzumab plus chemotherapy by Yu Lei (266919)

“…Additionally, after treatment, TMB significantly increased in non-responders, while CIN significantly decreased in responders.…”

Table 1_A murine model of gestational diabetes reveals MASLD risk and alterations in markers of hepatic mitochondrial metabolism.docx by Grace E. Shryack (21596426)

“…Hepatic markers (via mRNA and western blot analyses) of mitochondrial biogenesis, autophagy, mitophagy, activity, and function were assessed, as well as markers of inflammation and antioxidant status were evaluated.</p>Results<p>Progressing gestation in both CD and GDM dams significantly decreased protein and mRNA markers of hepatic mitochondrial biogenesis (Pgc1-α, Tfam), autophagy (Atg5, Sqstm1), mitophagy (Pink1, Bnip3) and lipid handling (Ampk, pAMPK/AMPK, FAS, ACC, pACC, Mttp) with a main effect for time (P<0.05). …”

Image 1_Mitochondrial DNA oxidation and content in different metabolic phenotypes of women with polycystic ovary syndrome.jpeg by Mailén Rojo (10802556)

“…</p>Results<p>Our findings showed that patients with PCOS had decreased mtDNA content and increased oxidation damage. …”

Data_Sheet_1_Analysis of spatial and temporal characteristics and evolution of green total factor productivity in agriculture in the lower Yellow River basin.xlsx by Junru He (20158257)

“…The results demonstrate that agricultural carbon emissions in the Lower Yellow River Basin gradually decreased throughout the study period. Furthermore, overall carbon emission efficiency improved, indicating significant potential for further emission reduction. …”

Data Sheet 1_Successional patterns of microbial communities across various stages of leaf litter decomposition in poplar plantations.pdf by Shuang Hu (182425)

“…With the decomposition of leaf litter, the total N content increased gradually, while other nutrients (C, P, K, cellulose and hemicellulose) decreased progressively. Litter characteristics had significant effects on microbial community structure: C/N, TK and residual hemicellulose (RH) were the primary driving factors affecting fungal community structure, whereas bacterial community structure was influenced by TK, RH, residual cellulose (RC) and lignin contents.…”

Data Sheet 1_Short-term structured dietary and exercise interventions delay diabetes onset in prediabetic patients: a prospective quasi-experimental study.pdf by Zhen Wang (72451)

“…The prevalence of abnormal blood glucose markers—FBG, 2h OGTT, and HbA1C—significantly decreased within each intervention group after short-term intervention and 6 months of follow-up. …”

Data Sheet 1_Case Report: Late diagnosis of McCune-Albright with severe kyphoscoliosis, acromegaly and tertiary hyperparathyroidism.pdf by Anna Bogusławska (20293545)

“…We present a case of a 40-year-old woman who was admitted to the Pulmonary Unit due to progressive pulmonary insufficiency secondary to severe scoliosis. …”

Supplementary Material for: Exclusively macular phenotype of non-syndromic MFSD8-related disease: A Case Report by figshare admin karger (2628495)

“…Introduction: The purpose of this report is to highlight the clinical phenotype and imaging findings in a patient with an exclusively macular phenotype of non-syndromic MFSD8-related disease, and to provide clinical evidence for pathogenicity reclassification of a variant of uncertain significance (VUS) MFSD8 c.291G>C (p.Trp97Cys). Case Presentation: A 47-year-old male with progressive vision loss exhibited symptoms indicative of maculopathy. …”

Presentation 1_Ischemia-reperfusion injury with a model of porcine whole-blood ex-vivo lung perfusion.pptx by Jean-Baptiste Menager (22163560)

“…Progressive microvasculopathy resulting in lymphangiectasia and peribronchovascular inflammatory infiltrates were seen in both groups.…”

Path regulates glial proliferation via the mTOR-S6K pathway. by Qian Dong (414788)

“…This results in a reduction in Path expression and the downstream mTOR-S6K pathway, causing a slowdown of BBB glial cell cycle progression. Path downregulation and defects in BBB expansion consequently led to a decrease in brain AAs, such as Leu, which hinders brain tumor protein synthesis to slow down tumor growth. …”

Data Sheet 2_Gut microbiota metabolite acetate mediates free fatty acid receptor 2 expression to alleviate atopic dermatitis.zip by Siqi Ye (9350531)

“…Acetate supplementation in AD mice significantly ameliorated 2,4-dinitrobenzene (DNCB)-induced dermatitis, as evidenced by reduced skin lesion severity, lower dermatitis scores, and decreased epidermal thickening. …”

Data Sheet 1_Gut microbiota metabolite acetate mediates free fatty acid receptor 2 expression to alleviate atopic dermatitis.zip by Siqi Ye (9350531)

“…Acetate supplementation in AD mice significantly ameliorated 2,4-dinitrobenzene (DNCB)-induced dermatitis, as evidenced by reduced skin lesion severity, lower dermatitis scores, and decreased epidermal thickening. …”

Data Sheet 1_Integration of hepatic lipidomics and transcriptomics reveals dysregulation of lipid metabolism in a golden hamster model of visceral leishmaniasis.zip by Dongmei Yuan (291583)

“…These findings suggest that Leishmania infection may regulate PC remodeling in the host liver and increase membrane phospholipid metabolism, resulting in the production of a series of lipid mediators that participate in immune regulation; this could have a significant impact on the survival of Leishmania in the host and on the progression of the disease.…”

<b><i>Streptococcus suis</i></b><b> </b><b>s</b><b>erotype</b><b> 5</b><b>: emerging </b><b>zoonotic </b><b>threat</b><b> with </b><b>distinct</b><b> genomic heterogeneity</b> by han zheng (20452463)

“…Thirty-two representative serotype 5 strains clustered into four groups: epidemic (E)(n=1), highly virulent plus (HV+)(n=4), HV(n=11), and virulent (V)(n=16). Virulence levels progressively decreased from the E group to HV+, HV, and V groups. …”

Image1_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.png by Huijun Zhou (60485)

“…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …”

DataSheet1_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.zip by Huijun Zhou (60485)

“…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …”