DataSheet1_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.zip by Huijun Zhou (60485)

“…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …”

Image2_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.png by Huijun Zhou (60485)

“…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …”

Image2_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.png by Huijun Zhou (60485)

“…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …”

Image1_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.png by Huijun Zhou (60485)

“…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …”

Image 1_Yishen-Huoxue formula alleviates renal interstitial fibrosis by attenuating hypoxia-induced renal cell injury and promoting angiogenesis via miR-210/HIF-1α pathway.jpeg by Mouying Du (21398510)

“…</p>Results<p>In vivo, YHF treatment significantly attenuated RIF, protected renal function, increased miR-210 expression, and decreased the expression of HIF-1α, BNIP3, and NIX in the serum exosomes of UUO rats. …”

Image 2_Yishen-Huoxue formula alleviates renal interstitial fibrosis by attenuating hypoxia-induced renal cell injury and promoting angiogenesis via miR-210/HIF-1α pathway.jpeg by Mouying Du (21398510)

“…</p>Results<p>In vivo, YHF treatment significantly attenuated RIF, protected renal function, increased miR-210 expression, and decreased the expression of HIF-1α, BNIP3, and NIX in the serum exosomes of UUO rats. …”

Table 1_Urinary and oral microbiota in Polish women: a pilot case-control study of breast cancer.docx by Anna Marciniak (12354534)

“…</p>Results<p>BC case urine microbiota contained an increased abundance of Corynebacterium (5.2-fold, but not significant) and Gammaproteobacteria including unknown genus and Pseudomonas (1.7- and 1.8-fold) and decreased abundance of Family XI (0.3-fold) and Bifidobacteriaceae (0.4-fold) compared to HCs. …”

Table 1_A real-world study of polyenyl phosphatidylcholine in the management of patients with metabolic dysfunction-associated fatty liver disease in China clinical practice.docx by Yi Pan (68170)

“…In the PPC group, baseline alanine transaminase (ALT) levels decreased at 12- and 24-weeks compared to those of the control group, but results were not significant. …”

<i>Streptococcus suis</i> serotype 5: Emerging zoonotic threat with distinct genomic heterogeneity by Xiyan Zhang (5680457)

“…Thirty-two representative serotype 5 strains were clustered into four groups: ultra-highly virulent (UV) (<i>n</i> = 1), highly virulent plus (HV⁺) (<i>n</i> = 4), HV (<i>n</i> = 11), and virulent (V) (<i>n</i> = 16). Virulence levels progressively decreased from the UV group to HV⁺, HV, and V groups. …”

Data Sheet 3_Aurantii Fructus extract alleviates DSS-induced colitis in mice via regulating NF-κB and Nrf2/HO-1 signaling pathways and modulating intestinal microbiota.zip by JunBao Yu (22442218)

“…Background<p>Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by progressive loss of intestinal function, highlighting an urgent need for effective therapeutics. …”

Data Sheet 1_Aurantii Fructus extract alleviates DSS-induced colitis in mice via regulating NF-κB and Nrf2/HO-1 signaling pathways and modulating intestinal microbiota.zip by JunBao Yu (22442218)

“…Background<p>Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by progressive loss of intestinal function, highlighting an urgent need for effective therapeutics. …”

Data Sheet 2_Aurantii Fructus extract alleviates DSS-induced colitis in mice via regulating NF-κB and Nrf2/HO-1 signaling pathways and modulating intestinal microbiota.zip by JunBao Yu (22442218)

“…Background<p>Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by progressive loss of intestinal function, highlighting an urgent need for effective therapeutics. …”

Data Sheet 1_Immunogenic cell death-related biomarkers in heart failure probed by transcriptome and single-cell sequencing.zip by Haoyue Wang (13138179)

“…In addition, the expression levels of CD163 and VSIG4 increased in subpopulations of monocytes and macrophages, whereas FPR1 showed a decreasing trend. RT-qPCR results confirmed significant down-regulation of CD163, FPR1, and VSIG4 in patients with HF and animal models.…”

DataSheet1_Early B lymphocyte subsets in blood predict prognosis in sepsis.docx by Yingqian Sun (7843838)

“…On day 7, the proportions and absolute counts of Tr and CD5⁺ B cells significantly decreased whereas the proportion of DN B cells significantly increased in non-survivors. …”

Data Sheet 1_Deciphering ERR family genes as prognostic and immunological biomarkers through pan-cancer analysis with validation in gallbladder cancer.pdf by Wanwan Gong (21187838)

“…All three ERRs demonstrate significant prognostic value across different cancers. …”

Table5_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... by Huijing Ren (19986303)

“…<p>Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder affecting millions of people worldwide, with no effective treatment currently available. …”

Table4_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... by Huijing Ren (19986303)

“…<p>Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder affecting millions of people worldwide, with no effective treatment currently available. …”

Table2_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... by Huijing Ren (19986303)

“…<p>Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder affecting millions of people worldwide, with no effective treatment currently available. …”

Table3_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... by Huijing Ren (19986303)

“…<p>Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder affecting millions of people worldwide, with no effective treatment currently available. …”

Table1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... by Huijing Ren (19986303)

“…<p>Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder affecting millions of people worldwide, with no effective treatment currently available. …”