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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant promise » significant rise (Expand Search), significant progress (Expand Search), significant positive (Expand Search)
promise decrease » point decrease (Expand Search)
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18161
Molecular signatures underlying multisensory gamma stimulation-associated cognitive benefits in the hippocampus.
Published 2025“…Color represents statistical significance after multiple testing adjustments. <b>E)</b> Signed bar plot displaying significant co-expression changes of the identified 7 gene modules in hippocampal excitatory neurons in stimulation vs ambient TsD65n mice. …”
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18162
Image 2_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif
Published 2025“…When both mitochondrial fractions were exposed to increasing mCa<sup>2+</sup> loads we observed decreased mCa<sup>2+</sup> sequestration in synaptic mitochondria as assessed by a significant increase in the steady-state free extra matrix Ca<sup>2+</sup> (ss[Ca<sup>2+</sup>]<sub>e</sub>) compared to non-synaptic mitochondria. …”
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18163
PTEN KD induces EMT in epithelial CRC cells.
Published 2024“…All significant comparisons are shown. * P ≤ 0.05, ** P ≤ 0.01, *** P ≤ 0.001, **** P ≤ 0.0001.…”
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18164
Supplementary file 1_The evolution of the global disease burden of polycystic ovary syndrome and the role of regional heterogeneity in high body mass index exposure: a spatiotempor...
Published 2025“…The overall disease burden decreased with age, particularly when high BMI exposure was below the 40th percentile (P40). …”
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18165
Datasheet2_Efficacy and safety of Danlou tablets in the treatment of stable angina pectoris with intermingled phlegm and blood stasis syndrome in coronary heart disease: a multicen...
Published 2024“…The activated partial thromboplastin time in the treatment group decreased significantly (P < 0.05). There was no statistically significant difference in the safety indicators and incidence of adverse reactions between the two groups.…”
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18166
Datasheet1_Efficacy and safety of Danlou tablets in the treatment of stable angina pectoris with intermingled phlegm and blood stasis syndrome in coronary heart disease: a multicen...
Published 2024“…The activated partial thromboplastin time in the treatment group decreased significantly (P < 0.05). There was no statistically significant difference in the safety indicators and incidence of adverse reactions between the two groups.…”
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18167
Table 1_Correlation of serum irisin levels with diabetic nephropathy: an exhaustive systematic appraisal and meta-analytical investigation.xls
Published 2025“…Background<p>Diabetic nephropathy (DN) is a major complication of diabetes, contributing significantly to end - stage renal disease. Irisin, an exercise - induced myokine, has been linked to metabolic disorders, but its relationship with DN remains unclear. …”
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18168
Datasheet2_Efficacy and safety of Danlou tablets in the treatment of stable angina pectoris with intermingled phlegm and blood stasis syndrome in coronary heart disease: a multicen...
Published 2024“…The activated partial thromboplastin time in the treatment group decreased significantly (P < 0.05). There was no statistically significant difference in the safety indicators and incidence of adverse reactions between the two groups.…”
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18169
Baumer-TPW_2023_Dopamine-Monocytes_PMID37251548.xlsx
Published 2025“…Furthermore, Filamin A (FLNA), a</p><p dir="ltr">prominent actin-crosslinking protein, that is known to regulate CCR2 recycling, significantly decreased in DA-</p><p dir="ltr">treated NCM (p < 0.05), indicating a reduction of CCR2 recycling. …”
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18170
Image 3_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif
Published 2025“…When both mitochondrial fractions were exposed to increasing mCa<sup>2+</sup> loads we observed decreased mCa<sup>2+</sup> sequestration in synaptic mitochondria as assessed by a significant increase in the steady-state free extra matrix Ca<sup>2+</sup> (ss[Ca<sup>2+</sup>]<sub>e</sub>) compared to non-synaptic mitochondria. …”
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18171
Data Sheet 1_Prevalence trends, population characteristics and treatment outcomes of tuberculosis combined with diabetes in Southwest China: a register-based retrospective study.do...
Published 2024“…</p>Results<p>From 2016 to 2022, the incidence rate of PTB in southwest China showed a decreasing trend (AAPC = -10.22, 95% CI: −11.49% ~ −8.94%), while the incidence rate of PTB-DM increased rapidly (AAPC = 14.25, 95% CI: 11.35% ~17.23%). …”
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18172
Presentation1_Systematic review of Buzhong Yiqi method in alleviating cancer-related fatigue: a meta-analysis and exploratory network pharmacology approach.PPTX
Published 2024“…Conversely, PFS, TCM syndrome score, and adverse reaction assessments significantly decreased. The primary active ingredients in its core drugs may exert a positive therapeutic effect on CRF by targeting molecules such as AKT1, IL6, IL1B, PTGS2, CASP3, ESR1, and BCL2, as well as through signaling pathways including TNF, IL17, TLR, NF-κB, and C-type lectin receptor.…”
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18173
Table 1_The evolution of the global disease burden of polycystic ovary syndrome and the role of regional heterogeneity in high body mass index exposure: a spatiotemporal analysis b...
Published 2025“…The overall disease burden decreased with age, particularly when high BMI exposure was below the 40th percentile (P40). …”
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18174
Altered spatial distribution of EPDCs in <i>Wt1</i><sup>Cre</sup>; <i>Sox9</i><sup>fl/fl</sup>; <i>R26</i><sup>mG</sup> hearts.
Published 2025“…Chi-square analysis indicates a significant shift in spatial distribution (p < 0.0001). …”
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18175
Supplementary Material for: Impact of Liraglutide 3.0 mg on Metabolic Dysfunction-Associated Steatotic Liver Disease in Individuals with Obesity: A Real-World Study
Published 2025“…Hepatic steatosis index (HSI) and non-alcoholic fatty liver disease (NAFLD) liver fat score also decreased significantly (HSI: 44.7 ± 6.2 to 42.2 ± 5.8 p<0.001; NAFLD liver fat score: 2.12 ± 2.90 to 0.43 ± 1.91, p<0.001). …”
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18176
DataSheet1_Synergistic combinations of Angelica sinensis for myocardial infarction treatment: network pharmacology and quadratic optimization approach.docx
Published 2024“…Further research revealed that Z-LIG/CGA treatment significantly increased IL-1R2 levels, significantly decreased IL-17RA levels, and inhibited the activation of p-STAT1, thereby alleviating cell apoptosis after MI. …”
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18177
Table 1_Guiren Runchang granules alleviate slow transit constipation in mice by modulating gut microbiota and short-chain fatty acids.docx
Published 2025“…Specifically, the relative abundance of the genera Alloprevotella and Muribaculum increased, while that of Prevotellaceae_NK3B31_group, Ruminococcus, and Lachnospiraceae_UCG-001 decreased. These microbiota changes were significantly correlated with SCFAs level, motility-related hormone concentrations, and defecation phenotype. …”
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18178
Heart looping variations in <i>Notch3</i> and <i>Nodal</i> compound mutants.
Published 2025“…(<b>F</b>) Brightfield images of wild type (f1), control <i>Notch3</i> heterozygote (f2) compared to homozygote <i>Nodal</i> mutants with decreased <i>Notch3</i> (f3) at E9.5, in a ventral view. …”
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18179
Development and validation of an ultra-performance liquid chromatography with tandem mass spectrometry method for determination of soluble repulsive guidance molecule A in human se...
Published 2024“…</p> <p>In CSF from patients with MCI and those with AD, total soluble RGMa was significantly decreasing to a median of 22.6 and 21.4 ng/ml, respectively.…”
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18180
Image 3_Cellular interactions and Ion channel signatures in atrial fibrillation remodeling: insights from single-cell analysis and machine learning.tif
Published 2025“…These subtypes exhibited significantly different distributions between AF and SR. …”