Data Sheet 1_Unraveling microbial shifts and plant growth responses in Chrysanthemum ‘Merlino’ due to artificial root exudates in horticultural substrates.pdf by Steffi Pot (10533497)

“…Introduction<p>Plant growth and health are significantly influenced by the composition, activity, and diversity of the rhizosphere microbiome. …”

Table 3_Antifungal activity of cinnamaldehyde against Aspergillus fumigatus involves disruption of the TCA cycle and protein metabolism.xlsx by Fang Li (41162)

“…Following treatment with CA, the protein expression of the putative translation initiation factor eIF4E3 (AFUB_051690), the putative leucyl-tRNA synthetase LeuRS (AFUB_093380), prolyl-tRNA synthetase ProRS (AFUB_010170) and the putative peptidyl-tRNA hydrolase Pth1 (AFUB_053480) exhibited a significant decrease. Moreover, deletion of pth1 resulted in a severe growth defect and hypersensitivity to CA, as evidenced by complete growth arrest at 30 and 45 μg/mL CA. …”

Table 2_Antifungal activity of cinnamaldehyde against Aspergillus fumigatus involves disruption of the TCA cycle and protein metabolism.xlsx by Fang Li (41162)

“…Following treatment with CA, the protein expression of the putative translation initiation factor eIF4E3 (AFUB_051690), the putative leucyl-tRNA synthetase LeuRS (AFUB_093380), prolyl-tRNA synthetase ProRS (AFUB_010170) and the putative peptidyl-tRNA hydrolase Pth1 (AFUB_053480) exhibited a significant decrease. Moreover, deletion of pth1 resulted in a severe growth defect and hypersensitivity to CA, as evidenced by complete growth arrest at 30 and 45 μg/mL CA. …”

Table 2_The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy.xlsx by Lei Zhang (38117)

“…Notably, both IgAN and MN patients showed a decrease in the abundance of certain specific microbial taxa. …”

Table 6_The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy.xlsx by Lei Zhang (38117)

“…Notably, both IgAN and MN patients showed a decrease in the abundance of certain specific microbial taxa. …”

Table 3_The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy.xlsx by Lei Zhang (38117)

“…Notably, both IgAN and MN patients showed a decrease in the abundance of certain specific microbial taxa. …”

Table 1_The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy.xlsx by Lei Zhang (38117)

“…Notably, both IgAN and MN patients showed a decrease in the abundance of certain specific microbial taxa. …”

Table 5_The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy.xlsx by Lei Zhang (38117)

“…Notably, both IgAN and MN patients showed a decrease in the abundance of certain specific microbial taxa. …”

Table 4_The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy.xlsx by Lei Zhang (38117)

“…Notably, both IgAN and MN patients showed a decrease in the abundance of certain specific microbial taxa. …”

DataSheet1_Morinda officinalis iridoid glycosides, as an inhibitor of GSK-3β, alleviates rheumatoid arthritis through inhibition of NF-κB and JAK2/STAT3 pathway.docx by Yi Shen (152956)

“…Knockdown GSK-3β gene could inhibit the paw swelling and inflammatory indicators, decrease the arthritis score and synovial hyperplasia, reduce the phosphorylation of p65 and STAT3 in AA mice, thereby suppressing the NF-κB and STAT3 signaling activation, and MOIG treatment had no significant effects on AA mice with si-GSK-3β.…”

Data Sheet 1_DYRK1A roles in human neural progenitors.docx by Jeremie Courraud (20871932)

“…In addition, DYRK1A-KD led to a reduction in p21 protein levels, despite an increase in the expression of a minor transcript variant for this gene, and a decrease in ERK pathway activation.</p>Discussion<p>Together, the DYRK1A interactome in hNSCs and the gene expression changes induced by its depletion highlight the significant role of DYRK1A in regulating hNSC proliferation. …”

Table 1_Unraveling the physiological and ultrastructural responses of wheat to combat cobalt stress and the protective role of Jania rubens related to antioxidant defense and cellu... by Gehad A. Ragab (18267912)

“…Wheat seedlings were subjected to cobalt chloride (150 mM) irrigation, which was previously primed with either water or J. rubens extract. Co stress significantly impaired growth by reducing water content and essential nutrients (K, Mg, and Fe), leading to a 42.42 and 23.8% decrease, respectively, in root and shoot biomasses, a 9% reduction in photosynthetic efficiency, visible chlorosis, and root thickening. …”

Table 1_MiR-216a-3p inhibits the cytotoxicity of primary natural killer cells.xlsx by Rowan Abdelbary (20589248)

“…Introduction<p>The role of miRNAs in regulating variable molecular functions has been sought by scientists for its promising utility in regulating the immune response and, hence, in treating various diseases. …”

Data Sheet 1_TREM-1 as a potential gatekeeper of neuroinflammatory responses: therapeutic validation and mechanistic insights in experimental traumatic brain injury.zip by Yunsheng Zhang (474242)

“…Background<p>Traumatic brain injury (TBI) triggers a cascade of neuroinflammatory responses mediated by microglial activation, which significantly contributes to secondary brain damage. …”

pone.0331193.t003 - by Carol Kotliar (22351525)

“…</p><p>Background</p><p>Cognitive decline is a significant concern in aging populations, with research suggesting that neuroplasticity and cognitive reserve can be enhanced through targeted cognitive training. …”

Effect of amikacin-humic acid combination on <i>Acinetobacter baumannii</i> biofilm: an <i>in vitro</i> and <i>in silico</i> study by Seetha Lakshmi Rajangam (19921021)

“…The images observed via Scanning Electron Microscope (SEM) showed a significant decrease in the biofilm matrix. Confocal Laser Scanning Microscope (CLSM) confirmed a reduction of the Z value of its three-dimensional structure. …”

Baseline characteristics by group. by Carol Kotliar (22351525)

“…</p><p>Background</p><p>Cognitive decline is a significant concern in aging populations, with research suggesting that neuroplasticity and cognitive reserve can be enhanced through targeted cognitive training. …”

Discovering a novel dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitor and its impact on tau phosphorylation and amyloid-β formation by Huang-Ju Tu (630766)

“…Although the development of DYRK1A inhibitors has significantly advanced in recent years, the selectivity of these drugs remains a critical challenge, potentially impeding further progress. …”

Presentation_1_Src Inhibition Attenuates Neuroinflammation and Protects Dopaminergic Neurons in Parkinson’s Disease Models.PDF by Hanyu Yang (8374881)

“…The results showed that inhibition of Src could significantly relieve microgliosis and decrease levels of inflammatory factors. …”

Image 5_Syzygium aromaticum extract mediated, sustainable silver nanoparticle synergetic with heterocyclic antibiotic clarithromycin and their antimicrobial activities.jpeg by Zehra Edis (20561825)

“…<p>Microorganisms are becoming resistant to drugs and antimicrobials, making it a significantly critical global issue. Nosocomial infections are resulting in alarmingly increasing rates of morbidity and mortality. …”