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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant promise » significant rise (Expand Search), significant progress (Expand Search), significant positive (Expand Search)
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1021
DataSheet1_D-mannose reduces oxidative stress, inhibits inflammation, and increases treg cell proportions in mice with ulcerative colitis.pdf
Published 2024“…D-mannose treatment significantly reduced inflammation by decreasing the expression of proinflammatory cytokines and inflammation mediators. …”
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1022
SEAwise Report on the impacts of fisheries on stocks and landings under SEAwise EBFM
Published 2025“…The ecosystem model generally showed less optimistic outcomes under climate change, with significant decreases in biomass and catches in both the Celtic and North Seas. …”
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1023
Metabolic flux analysis revealed key roles of ArcB in ADI pathway and IlvC in BCAA biosynthesis during <i>streptococcus suis</i> anaerobic growth and infection
Published 2025“…Transcriptomic analysis found a significant suppression of many central metabolic genes during anaerobic growth of <i>S. suis</i>. …”
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1024
<b>Metabolic flux analysis revealed </b><b>key roles of </b><b>ArcB</b><b> in ADI pathway and IlvC in BCAA </b><b>biosynthesis </b><b>during </b><b><i>Streptococcus suis</i></b><b>...
Published 2025“…Transcriptome analysis found a significant suppression of many central metabolic genes during anaerobic growth of <i>S. suis</i>. …”
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1025
Data Sheet 1_Anti-neoplastic effects of the antipsychotic drug penfluridol in preclinical prostate cancer models.pdf
Published 2025“…</p>Results<p>Penfluridol significantly reduced the viability of a panel of human PCa cells, induced apoptosis by increasing caspase-3/7 levels and decreased the number of PCa stem cells in vitro. …”
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1026
Data Sheet 2_Anti-neoplastic effects of the antipsychotic drug penfluridol in preclinical prostate cancer models.docx
Published 2025“…</p>Results<p>Penfluridol significantly reduced the viability of a panel of human PCa cells, induced apoptosis by increasing caspase-3/7 levels and decreased the number of PCa stem cells in vitro. …”
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1027
Supplementary Material for: Dose-effect Relationship of Hyperbaric Oxygen Therapy in Rats with Amnestic Mild Cognitive Impairment
Published 2025“…Results:After hyperbaric oxygen treatment, compared with the aMCI group, the escape latency of each HBO subgroup was significantly shortened (p<0.001). The 2.0ATA subgroup (p=0.001), 2.2ATA subgroup (p=0.001)and 2.5ATA subgroup ( p=0.002) significantly increased the number of platform crossings.the levels of SOD were significantly increased in1.6ATA subgroup (p=0.019), 1.8ATA subgroup(p =0.003), 2.0ATA subgroup(p=0.010 ) and 2.2ATA group(p=0.016) and MDA contents were significantly decreased in the 1.6ATA subgroup(p=0.015), 1.8ATA subgroup(p =0.012), 2.0ATA subgroup(p=0.002), and 2.2ATA subgroups (p<0.001), and the levels of eNOS were significantly decreased in the 1.8ATA subgroup(p=0.007) and 2.0ATA subgroup (p=0.029),and the expression of nNOS were significantly decreased in the 1.8ATA subgroup (p=0.006),2.0ATA subgroup (p<0.001) and the 2.2ATA subgroup ( p< 0.001). …”
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1028
Table 1_Inflammatory biomarkers and therapeutic potential of milk exosome-mediated CCL7 siRNA in murine intestinal ischemia-reperfusion injury.docx
Published 2025“…</p>Methods<p>Using transcriptome sequencing in a mouse model of IIRI, we identified potential biomarkers that were significantly upregulated in the IIRI group compared to the sham group. …”
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1029
Data Sheet 1_Antibacterial effects of coniferyl alcohol-derived dehydrogenation polymer on chlamydial infection in vitro.pdf
Published 2025“…</p>Conclusion<p>Our results suggest that DHP/Alg is a promising therapeutic option against chlamydial infections. …”
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1030
Table 1_Serendipita indica-dominated synthetic microbial consortia enhanced tartary buckwheat growth and improved its tolerance to drought stress.docx
Published 2025“…Plant growth-promoting (PGP) microorganisms hold promise for addressing these challenges. In this study, we investigated the effects of Serendipita indica inoculation on the root-associated microbial communities of tartary buckwheat. …”
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1031
Supplementary Material for: Efficacy of Spray Cryotherapy on Airway Secretions in Canine Models of Chronic Bronchitis and Mechanism Insights
Published 2025“…SCT treatment reduced mucus and pulmonary resistance, improved bronchial structure, and decreased goblet cells. SCT significantly reduced BALF mucin, MUC5AC, MUC5B, acetylcholine, IL-6, INF-γ, TNF-α, and IL-10, and bronchial MUC5AC and CHRM3. …”
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1032
Table 1_A daily positive work reflection intervention for psychological distress among Chinese nurses: a pilot randomized controlled trial.docx
Published 2025“…</p>Conclusions<p>Results suggest that a daily positive work reflection intervention is a feasible and promising intervention for decreasing Chinese nurses' psychological distress. …”
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1033
Image 10_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg
Published 2025“…Introduction<p>Immune checkpoint blockade (ICB) therapy has shown promise in treating advanced colorectal cancer, particularly in patients with microsatellite instability-high (MSI-H) tumors. …”
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1034
Image 3_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg
Published 2025“…Introduction<p>Immune checkpoint blockade (ICB) therapy has shown promise in treating advanced colorectal cancer, particularly in patients with microsatellite instability-high (MSI-H) tumors. …”
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1035
Image 7_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.tif
Published 2025“…Introduction<p>Immune checkpoint blockade (ICB) therapy has shown promise in treating advanced colorectal cancer, particularly in patients with microsatellite instability-high (MSI-H) tumors. …”
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1036
Image 2_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif
Published 2025“…</p>Results<p>Behavioral tests revealed that low-frequency EA significantly alleviated depressive-like behaviors and cognitive impairment. …”
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1037
Image 6_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg
Published 2025“…Introduction<p>Immune checkpoint blockade (ICB) therapy has shown promise in treating advanced colorectal cancer, particularly in patients with microsatellite instability-high (MSI-H) tumors. …”
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1038
Image 1_Therapeutic potential and mechanistic insights of silibinin targeting cancer-associated fibroblasts in colorectal cancer.jpeg
Published 2025“…Consistently, in vitro experiments demonstrated that SB significantly decreased both protein and mRNA levels of α-SMA and POSTN in fibroblasts (colonic myofibroblast CCD-18Co cell lines.) co-cultured with CRC cell lines (human colorectal adenocarcinoma SW480 and RKO cell lines). …”
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1039
Image 8_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg
Published 2025“…Introduction<p>Immune checkpoint blockade (ICB) therapy has shown promise in treating advanced colorectal cancer, particularly in patients with microsatellite instability-high (MSI-H) tumors. …”
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1040
Image 15_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg
Published 2025“…Introduction<p>Immune checkpoint blockade (ICB) therapy has shown promise in treating advanced colorectal cancer, particularly in patients with microsatellite instability-high (MSI-H) tumors. …”