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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant promise » significant rise (Expand Search), significant progress (Expand Search), significant positive (Expand Search)
promise decrease » point decrease (Expand Search)
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1441
Image 1_CD155 as a therapeutic target in alveolar echinococcosis: insights from an Echinococcus multilocularis infection mouse model.tif
Published 2025“…Targeting CD155 reverses this immunosuppression and mitigates hepatic pathology, highlighting CD155 as a promising therapeutic target for AE.</p>…”
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1442
List of primers used in quantitative RT-PCR.
Published 2025“…The results demonstrated that NPs significantly reduced basal rot symptoms and decreased the Area Under the Disease Progress Curve (AUDPC) values. …”
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1443
Image 3_Neonatal supplementation of oleamide during suckling ameliorates maternal postpartum sleep interruption-induced neural impairment and endocannabinoid dysfunction in early a...
Published 2025“…Introduction<p>Postpartum sleep disturbances in women are common and can significantly affect maternal mental health and breastfeeding. …”
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1444
Table 1_Microglial adenosine A2A receptor in the paraventricular thalamic nucleus regulates pain sensation and analgesic effects independent of opioid and cannabinoid receptors.doc...
Published 2024“…Pharmacological activation of local PVT A<sub>2A</sub>R with its agonist CGS21680 induced significantly decreased 50% paw withdrawal threshold (50%PWTs) and paw withdrawal latency (PWLs), as measured by the Von Frey test and Hargreaves test in adult mice. …”
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1445
Data Sheet 1_Chrysin sensitizes glioblastoma cells and spheroids to temozolomide treatment by reducing EMT and stemness phenotypes, as well as targeting multidrug resistance protei...
Published 2025“…In 3D spheroid models, co-treatments significantly impaired growth and viability.</p>Conclusion<p>These findings suggest that CHR may be a promising adjuvant to TMZ therapy, providing novel insights into overcoming chemoresistance in GB treatment.…”
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1446
Image 1_Microglial adenosine A2A receptor in the paraventricular thalamic nucleus regulates pain sensation and analgesic effects independent of opioid and cannabinoid receptors.tif
Published 2024“…Pharmacological activation of local PVT A<sub>2A</sub>R with its agonist CGS21680 induced significantly decreased 50% paw withdrawal threshold (50%PWTs) and paw withdrawal latency (PWLs), as measured by the Von Frey test and Hargreaves test in adult mice. …”
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1447
Novel Vanillic Acid-Loaded <i>In Situ</i> Gels: Development, Characterization, <i>In Vitro</i> Evaluation for Enhanced Wound Healing and Skin Irritation Test
Published 2025“…Moreover, IN15-VA significantly reduced prostaglandin E2 levels, controlled IL-6 increase and exhibited non-irritating properties. …”
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1448
Data Sheet 2_Renewable energy consumption optimization allocation strategy for a regional microgrid based on a shared energy storage mechanism.pdf
Published 2025“…<p>With the continuous maturation of the sharing economy model, the shared energy storage station service model emerges as a promising user-side energy storage application. This article proposes a bilayer optimal configuration method for regional microgrid systems, leveraging shared energy storage station services. …”
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1449
Image 2_Neonatal supplementation of oleamide during suckling ameliorates maternal postpartum sleep interruption-induced neural impairment and endocannabinoid dysfunction in early a...
Published 2025“…Introduction<p>Postpartum sleep disturbances in women are common and can significantly affect maternal mental health and breastfeeding. …”
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1450
Image 1_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff
Published 2025“…These results suggest that melatonin is a promising therapeutic candidate for neuroinfections caused by flaviviruses.…”
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1451
Image 2_Microglial adenosine A2A receptor in the paraventricular thalamic nucleus regulates pain sensation and analgesic effects independent of opioid and cannabinoid receptors.tif
Published 2024“…Pharmacological activation of local PVT A<sub>2A</sub>R with its agonist CGS21680 induced significantly decreased 50% paw withdrawal threshold (50%PWTs) and paw withdrawal latency (PWLs), as measured by the Von Frey test and Hargreaves test in adult mice. …”
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1452
Image 3_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff
Published 2025“…These results suggest that melatonin is a promising therapeutic candidate for neuroinfections caused by flaviviruses.…”
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1453
Data Sheet 1_Therapeutic potential of Cordyceps militaris cultivated with Ginkgo biloba seeds for alleviating western diet-induced type 2 diabetes and diabetic nephropathy.pdf
Published 2025“…Key biochemical markers, including blood glucose, triglycerides, cholesterol, blood urea nitrogen (BUN), and creatinine, were significantly improved after treatment. Histopathologic analysis revealed restored renal morphology, reduced fibrosis and decreased amyloid deposition. …”
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1454
Image 2_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff
Published 2025“…These results suggest that melatonin is a promising therapeutic candidate for neuroinfections caused by flaviviruses.…”
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1455
Image 1_Neonatal supplementation of oleamide during suckling ameliorates maternal postpartum sleep interruption-induced neural impairment and endocannabinoid dysfunction in early a...
Published 2025“…Introduction<p>Postpartum sleep disturbances in women are common and can significantly affect maternal mental health and breastfeeding. …”
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1456
Data Sheet 1_Identification of a multiple DAMP scavenger mimicking the DAMP-binding site of TLR4 to ameliorate lethal sepsis.pdf
Published 2025“…Additionally, OP18-treated septic mice demonstrated reduced blood organ injury markers, decreased proinflammatory cytokine levels, attenuated ALI, and improved survival. …”
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1457
pH sensitive lipid polymeric hybrid nanoparticle (LPHNP) of paclitaxel and curcumin for targeted delivery in breast cancer
Published 2024“…MTT-assay studies revealed enhanced cytotoxicity of CUR and PTX as LPHNPs showing IC<sub>50</sub> value of free CUR & PTX 480.06 µg/mL decreasing to 282.97 µg/mL for CS-CUR-PTX-LPHNPs. <i>In vivo</i> pharmacokinetic evaluations in rats confirmed significantly improved bioavailability, with a 3.8-fold increase in AUC for CUR and a 6.6-fold increase for PTX. …”
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1458
Data Sheet 1_A novel bioactive peptide-peptoid hybrid of alpha-calcitonin gene-related peptide protects against pressure-overload induced heart failure.docx
Published 2025“…NMEG-CGRP administration significantly attenuated these TAC-induced adverse cardiac effects in the HF mice.…”
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1459
Data Sheet 1_Efficacy and safety of anlotinib combined with 125I seed implantation for iodine-refractory thyroid cancer.docx
Published 2025“…This combination may offer a promising therapeutic option for RAIR-DTC, pending further validation in larger studies.…”
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1460
ELOVL6 as a Therapeutic Target: Disrupting c-MYC-Driven Lipid Metabolism to Enhance Chemotherapy in Pancreatic Cancer
Published 2025“…Altogether, these results position ELOVL6 as a promising therapeutic target in the treatment of PDAC.…”