Table 4_Association of SPP1 and NCAPG genes with milk production traits in Chinese Holstein cows: polymorphism and functional validation analysis.xlsx by Chuanchuan Wang (12228518)

“…(BMECs), down-regulated the expression of PCNA, CDK2 and CCND1, up-regulated the expression of BAX and BAD, and promoted apoptosis. Reduced triglyceride synthesis in BMECs, down-regulated the expression of DGAT1, DGAT2, LPIN1, and AGPAT6.SPP1 and NCAPG are involved in the synthesis of milk proteins, and interfering with SPP1 and NCAPG decreased the secretion of β-casein, κ-casein, and αs1-casein, as well as up-regulated the CSN2 and CSN3 expression. …”

Gastric microbiome composition accompanied with the <i>Helicobacter pylori</i> related DNA methylation anomaly by Takuya Shijimaya (16928363)

“…Multivariate analysis demonstrated older age (t = 3.46, <i>p</i> = 0.0007), <i>H. pylori</i> infection (t = 9.99, <i>p</i> < 0.0001) and lower bacterial alfa diversity (Shannon index: t = -2.34, <i>p</i> = 0.02) were significantly associated with CGI hypermethylation. In genus or family levels, increased abundance of <i>Helicobacter</i> was associated with hyper CGI methylation with strongest correlation, while decreased abundance of four bacteria (<i>Intrasporangiaceae family, Macellibacteroides</i>, <i>Peptostreptococcus</i> and <i>Dietziaceae family</i>) was also associated with hyper CGI methylation. …”

Table 5_Association of SPP1 and NCAPG genes with milk production traits in Chinese Holstein cows: polymorphism and functional validation analysis.xlsx by Chuanchuan Wang (12228518)

“…(BMECs), down-regulated the expression of PCNA, CDK2 and CCND1, up-regulated the expression of BAX and BAD, and promoted apoptosis. Reduced triglyceride synthesis in BMECs, down-regulated the expression of DGAT1, DGAT2, LPIN1, and AGPAT6.SPP1 and NCAPG are involved in the synthesis of milk proteins, and interfering with SPP1 and NCAPG decreased the secretion of β-casein, κ-casein, and αs1-casein, as well as up-regulated the CSN2 and CSN3 expression. …”

Table 1_Pingwei Powder alleviates high-fat diet-induced colonic inflammation by modulating microbial metabolites SCFAs.xlsx by Tangjuan Liu (2634649)

“…Experimental validation showed that PWP significantly downregulated the levels of PI3K, pAKT/AKT, and pmTOR/mTOR in colonic tissue, thereby enhancing autophagy in colonic epithelial cells, as evidenced by decreased levels of P62 and increased LC3B-II/LC3B-I ratios. …”

Table 1_VdAHA1 positively regulate pathogenicity in Verticillium dahliae.docx by Dongpo Li (3612152)

“…The VdAHA1 knockout mutants showed increased drug sensitivity to ergosterol synthesis pathway, significantly inhibiting ergosterol biosynthesis. The VdAHA1 knockout mutant strain also showed decreased melanin in microsclerotia by reduced expression of microsclerotia and melanin related genes Vaflm, Vayg1, and VdSCD. …”

Image 3_VdAHA1 positively regulate pathogenicity in Verticillium dahliae.jpeg by Dongpo Li (3612152)

“…The VdAHA1 knockout mutants showed increased drug sensitivity to ergosterol synthesis pathway, significantly inhibiting ergosterol biosynthesis. The VdAHA1 knockout mutant strain also showed decreased melanin in microsclerotia by reduced expression of microsclerotia and melanin related genes Vaflm, Vayg1, and VdSCD. …”

Image 1_VdAHA1 positively regulate pathogenicity in Verticillium dahliae.jpeg by Dongpo Li (3612152)

“…The VdAHA1 knockout mutants showed increased drug sensitivity to ergosterol synthesis pathway, significantly inhibiting ergosterol biosynthesis. The VdAHA1 knockout mutant strain also showed decreased melanin in microsclerotia by reduced expression of microsclerotia and melanin related genes Vaflm, Vayg1, and VdSCD. …”

Image 2_VdAHA1 positively regulate pathogenicity in Verticillium dahliae.jpeg by Dongpo Li (3612152)

“…The VdAHA1 knockout mutants showed increased drug sensitivity to ergosterol synthesis pathway, significantly inhibiting ergosterol biosynthesis. The VdAHA1 knockout mutant strain also showed decreased melanin in microsclerotia by reduced expression of microsclerotia and melanin related genes Vaflm, Vayg1, and VdSCD. …”

Image 4_VdAHA1 positively regulate pathogenicity in Verticillium dahliae.jpeg by Dongpo Li (3612152)

“…The VdAHA1 knockout mutants showed increased drug sensitivity to ergosterol synthesis pathway, significantly inhibiting ergosterol biosynthesis. The VdAHA1 knockout mutant strain also showed decreased melanin in microsclerotia by reduced expression of microsclerotia and melanin related genes Vaflm, Vayg1, and VdSCD. …”

Data Sheet 1_Differential regulation of soil microecology in crop rotation systems of maize, seed pumpkin, and processing tomato.docx by Xingxing Liu (715957)

“…Notably, the SLa treatment significantly decreased soil total potassium content by 13.6%. …”

Differences between reproductive and constructive uses during school lockdown and after the pandemic. by Juan-Ignacio Pozo (20421678)

“…<p>The figure shows that while learning activities significantly decreased after the pandemic, constructive learning activities remained virtually the same in both periods.…”

Analysis of errors of the AI model on accuracy and decision times for different tasks during the retrospective reader study. (a) by Kerol Djoumessi (21349992)

“…When the AI model is correct, the explanation decreases decision time significantly, while it does not increase the decision time for incorrect decisions.…”

IntegraBrain: A multi-modal neural interface for the detection and suppression of focal epilepsy by Spencer Moore (8440863)

“…Long-term implantation of these devices would risk inducing significant compression injury and localised glial scaring over time.…”

Table_1_RETRACTED: High glucose induced HIF-1α/TREK1 expression and myometrium relaxation during pregnancy.docx by Tengteng Li (9104024)

“…The contractility of cultured HUSMCs was significantly decreased under high glucose levels, which was consistent with increased expression of HIF-1α and TREK1 proteins. …”

The interaction of COVID-19 and sociodemographic factors on pediatric rehabilitation service initiation by Lynn R. Tanner (21311527)

“…</p> <p>During COVID, service initiation decreased significantly by 23% (<i>p</i> < 0.001), whereas referral rates remained stable. …”

Legacy effects of trampling on SOC, POC, and MOC​ by yanchun liu (19650631)

“…Our results showed that in 2015, soil inorganic nitrogen (SIN), fine root biomass (FRB), and microbial biomass C decreased significantly with increasing trampling intensity, whereas the negative effects weakened over the recovery period. …”

Effects of individual and community-level metabolism of nematodes on the soil organic carbon pool under different precipitation patterns by Ailin Zhang (21536480)

“…<p dir="ltr">The water reduction treatments significantly increased SOC content while decreasing the ratio of passive organic carbon to total organic carbon (ROC/SOC). …”

Table 1_Revised Peck’s formula for estimating pipeline’s settlement under the coupling effect of tunnelling and vehicle load.xlsx by Shu Peng (642390)

“…The results reveal that the settlement of soil and pipeline caused by tunnelling decreases with decreasing burial depth; the dynamic settlement of the sewage pipe and ground surface is decreasing rapidly as the burial depth increases. …”

<i>STAG2</i> mutant organoids display characteristics suggestive of increased crypt proliferation when cultured in differentiation media. by Wei Ni Yew (22439334)

“…In a similar way, <i>STAG2</i> mutant organoids also exhibited significantly decreased circularity (b) and increased crypt proliferation (c) compared with <i>STAG2</i> wildtype organoids. …”

Data Sheet 1_Clinical pharmacist interventions in medication review for medication optimization in older hospitalized adults with mental disorders and somatic comorbidities: eviden... by Matej Stuhec (5643284)

“…The number of PIMs also significantly decreased (p < 0.001), with reductions of 29.5% (from 308 to 217) based on the Priscus List and 17.5% (from 343 to 283) according to the Beers Criteria. …”